EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
1.1.1.205 | IMP dehydrogenase |
K-562 cell |
- |
347916, 347918, 705494 |
1.1.1.37 | malate dehydrogenase |
K-562 cell |
- |
762064 |
1.1.1.39 | malate dehydrogenase (decarboxylating) |
K-562 cell |
erythroleukemia cells |
713373 |
1.1.1.40 | malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) |
K-562 cell |
- |
761332 |
1.1.1.44 | phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating) |
K-562 cell |
- |
741037 |
1.10.5.1 | ribosyldihydronicotinamide dehydrogenase (quinone) |
K-562 cell |
- |
725669 |
1.11.1.24 | thioredoxin-dependent peroxiredoxin |
K-562 cell |
0.0033 mg Prx I per mg of soluble protein Prx I, 0.002 mg Prx II per mg of soluble protein, less than 0.0003 mg Prx III per mg of soluble protein, 0.0003 mg Prx V per mg of soluble protein and more than 0.005 mg Prx VI per mg of soluble protein |
655756 |
1.13.11.34 | arachidonate 5-lipoxygenase |
K-562 cell |
- |
743129 |
1.14.11.53 | mRNA N6-methyladenine demethylase |
K-562 cell |
- |
763823 |
1.14.11.67 | [histone H3]-trimethyl-L-lysine4 demethylase |
K-562 cell |
- |
744657 |
1.14.14.94 | leukotriene-B4 20-monooxygenase |
K-562 cell |
- |
703413 |
1.17.4.1 | ribonucleoside-diphosphate reductase |
K-562 cell |
a myelogenous leukemia cell line |
688283 |
1.3.3.4 | protoporphyrinogen oxidase |
K-562 cell |
- |
686939 |
1.3.5.1 | succinate dehydrogenase |
K-562 cell |
- |
711232 |
1.4.3.5 | pyridoxal 5'-phosphate synthase |
K-562 cell |
2.5% of the activity in liver |
655483 |
1.5.1.2 | pyrroline-5-carboxylate reductase |
K-562 cell |
- |
763322 |
1.7.1.7 | GMP reductase |
K-562 cell |
- |
659550 |
1.8.1.9 | thioredoxin-disulfide reductase |
K-562 cell |
- |
688735 |
2.1.1.137 | arsenite methyltransferase |
K-562 cell |
- |
718748, 733451 |
2.1.1.319 | type I protein arginine methyltransferase |
K-562 cell |
- |
756861 |
2.1.1.359 | [histone H3]-lysine36 N-trimethyltransferase |
K-562 cell |
- |
720843 |
2.1.1.360 | [histone H3]-lysine79 N-trimethyltransferase |
K-562 cell |
- |
753750 |
2.1.1.6 | catechol O-methyltransferase |
K-562 cell |
- |
735306 |
2.1.1.67 | thiopurine S-methyltransferase |
K-562 cell |
- |
720181 |
2.3.1.37 | 5-aminolevulinate synthase |
K-562 cell |
- |
718890, 757677 |
2.3.1.37 | 5-aminolevulinate synthase |
K-562 cell |
ALAS2 is expressed exclusively in erythroid cells |
671812 |
2.3.1.37 | 5-aminolevulinate synthase |
K-562 cell |
sodium butyrate treatment activates ALAS2 gene transcription |
685795 |
2.3.1.50 | serine C-palmitoyltransferase |
K-562 cell |
- |
736416 |
2.3.1.B43 | protein-lysine desuccinylase (NAD+) |
K-562 cell |
- |
755970 |
2.3.2.13 | protein-glutamine gamma-glutamyltransferase |
K-562 cell |
leukemia cell line |
659317 |
2.3.2.2 | gamma-glutamyltransferase |
K-562 cell |
- |
702160 |
2.3.3.8 | ATP citrate synthase |
K-562 cell |
- |
672878 |
2.4.1.152 | 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase |
K-562 cell |
- |
639528 |
2.4.1.41 | polypeptide N-acetylgalactosaminyltransferase |
K-562 cell |
enzyme form GalNAc-T1 |
636809 |
2.4.1.41 | polypeptide N-acetylgalactosaminyltransferase |
K-562 cell |
enzyme form GalNAc-T3 |
636809 |
2.4.1.41 | polypeptide N-acetylgalactosaminyltransferase |
K-562 cell |
human trophoblast, enzyme form GalNAc-T1 |
636809 |
2.4.1.41 | polypeptide N-acetylgalactosaminyltransferase |
K-562 cell |
low activity, enzyme form GalNAc-T11 |
636809 |
2.4.1.41 | polypeptide N-acetylgalactosaminyltransferase |
K-562 cell |
low activity, enzyme form GalNAc-T4 |
636809 |
2.4.1.68 | glycoprotein 6-alpha-L-fucosyltransferase |
K-562 cell |
- |
736414 |
2.4.1.69 | type 1 galactoside alpha-(1,2)-fucosyltransferase |
K-562 cell |
undifferentiated leukemic cells, K562, that have erythroid characteristics |
489365 |
2.4.2.1 | purine-nucleoside phosphorylase |
K-562 cell |
- |
703162 |
2.4.2.12 | nicotinamide phosphoribosyltransferase |
K-562 cell |
- |
758918 |
2.4.2.12 | nicotinamide phosphoribosyltransferase |
K-562 cell |
leukemia cell line |
661421 |
2.4.2.19 | nicotinate-nucleotide diphosphorylase (carboxylating) |
K-562 cell |
- |
758726 |
2.4.2.26 | protein xylosyltransferase |
K-562 cell |
expresson of xylosyltransferase 2, no expression of xylosyltransferase 1 |
679132 |
2.4.2.26 | protein xylosyltransferase |
K-562 cell |
XT-I mRNA is not expressed but XT-II mRNA |
702090 |
2.4.3.1 | beta-galactoside alpha-(2,6)-sialyltransferase |
K-562 cell |
a leukemia cell line, the enzyme is expressed during the induction of megakaryocytic differentiation |
675938 |
2.4.3.3 | alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase |
K-562 cell |
hematopoietic cell line, high ST6GalNAc-I expression |
636809 |
2.4.3.8 | alpha-N-acetylneuraminate alpha-2,8-sialyltransferase |
K-562 cell |
- |
738434, 764812 |
2.4.3.9 | lactosylceramide alpha-2,3-sialyltransferase |
K-562 cell |
- |
735622 |
2.4.3.9 | lactosylceramide alpha-2,3-sialyltransferase |
K-562 cell |
GM3 synthase expression analysis, the enzyme is expressed during the induction of megakaryocytic differentiation in human leukemia K562 cells by phorbol 12-myristate 13-acetate depending upon the PKC/ERK/CREB pathway, overview |
675938 |
2.4.3.9 | lactosylceramide alpha-2,3-sialyltransferase |
K-562 cell |
treatment of phorbol 12-myristate 13-acetate induced cells with protein kinase C inhibitor Go6976 or extracellular signal-regulated kinase inhibitor U0126 reduces expression of GM3 synthase. Activation of extracellular signal-regulated kinase and cAMP response element binding protein is prevented by pretreatment with Go6976 and U0126 |
688984 |
2.5.1.18 | glutathione transferase |
K-562 cell |
a myeloid leukemia cell line |
674457 |
2.5.1.29 | geranylgeranyl diphosphate synthase |
K-562 cell |
- |
688602 |
2.7.1.107 | diacylglycerol kinase (ATP) |
K-562 cell |
- |
761590 |
2.7.1.113 | deoxyguanosine kinase |
K-562 cell |
- |
671801 |
2.7.1.113 | deoxyguanosine kinase |
K-562 cell |
no increase in activity when cells proliferate |
671801 |
2.7.1.48 | uridine/cytidine kinase |
K-562 cell |
UCK2 is the predominant UCK isozyme expressed in K562 cells |
758919 |
2.7.1.60 | N-acylmannosamine kinase |
K-562 cell |
- |
641741, 661666 |
2.7.1.67 | 1-phosphatidylinositol 4-kinase |
K-562 cell |
- |
721713 |
2.7.1.74 | deoxycytidine kinase |
K-562 cell |
- |
671801 |
2.7.1.91 | sphingosine kinase |
K-562 cell |
- |
704087 |
2.7.10.2 | non-specific protein-tyrosine kinase |
K-562 cell |
- |
676883, 702857 |
2.7.11.1 | non-specific serine/threonine protein kinase |
K-562 cell |
chromic myelogenous leukemia cell line, isozyme PKNbeta |
662053 |
2.7.11.10 | IkappaB kinase |
K-562 cell |
- |
722690 |
2.7.11.17 | Ca2+/calmodulin-dependent protein kinase |
K-562 cell |
- |
691612 |
2.7.11.2 | [pyruvate dehydrogenase (acetyl-transferring)] kinase |
K-562 cell |
- |
723186 |
2.7.11.21 | polo kinase |
K-562 cell |
- |
703030 |
2.7.11.22 | cyclin-dependent kinase |
K-562 cell |
- |
738159 |
2.7.11.26 | tau-protein kinase |
K-562 cell |
- |
704796 |
2.7.11.30 | receptor protein serine/threonine kinase |
K-562 cell |
- |
740256 |
2.7.11.30 | receptor protein serine/threonine kinase |
K-562 cell |
hematopoietic cells |
691460 |
2.7.11.31 | [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase |
K-562 cell |
- |
761034 |
2.7.4.14 | UMP/CMP kinase |
K-562 cell |
chronic myelogenous leukemia cell |
645160 |
2.7.4.14 | UMP/CMP kinase |
K-562 cell |
chronic myelogenous leukemia cell line |
693063 |
2.7.7.23 | UDP-N-acetylglucosamine diphosphorylase |
K-562 cell |
- |
762291 |
2.7.8.27 | sphingomyelin synthase |
K-562 cell |
- |
722907 |
2.8.1.7 | cysteine desulfurase |
K-562 cell |
- |
645625 |
3.1.1.7 | acetylcholinesterase |
K-562 cell |
leukemic cells |
114162 |
3.1.13.4 | poly(A)-specific ribonuclease |
K-562 cell |
- |
729551 |
3.1.21.1 | deoxyribonuclease I |
K-562 cell |
- |
664843, 707845 |
3.1.26.4 | ribonuclease H |
K-562 cell |
K562 |
134409 |
3.1.3.16 | protein-serine/threonine phosphatase |
K-562 cell |
- |
655987 |
3.1.3.43 | [pyruvate dehydrogenase (acetyl-transferring)]-phosphatase |
K-562 cell |
- |
730051 |
3.1.3.5 | 5'-nucleotidase |
K-562 cell |
- |
750020 |
3.1.3.86 | phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase |
K-562 cell |
- |
714601, 750315 |
3.1.4.1 | phosphodiesterase I |
K-562 cell |
- |
208356 |
3.1.4.3 | phospholipase C |
K-562 cell |
human erythroleukemia cell line |
652678 |
3.1.4.35 | 3',5'-cyclic-GMP phosphodiesterase |
K-562 cell |
- |
691533 |
3.1.4.4 | phospholipase D |
K-562 cell |
a myeloid cell line |
707543 |
3.2.1.18 | exo-alpha-sialidase |
K-562 cell |
- |
666315, 696394 |
3.2.1.51 | alpha-L-fucosidase |
K-562 cell |
- |
655418 |
3.4.11.1 | leucyl aminopeptidase |
K-562 cell |
- |
665925, 753402 |
3.4.11.18 | methionyl aminopeptidase |
K-562 cell |
- |
699818 |
3.4.11.2 | membrane alanyl aminopeptidase |
K-562 cell |
- |
663607 |
3.4.11.6 | aminopeptidase B |
K-562 cell |
chronic |
36005 |
3.4.11.6 | aminopeptidase B |
K-562 cell |
chronic myeloid leukemia cell line |
665109, 666799 |
3.4.14.10 | tripeptidyl-peptidase II |
K-562 cell |
- |
731223 |
3.4.21.108 | HtrA2 peptidase |
K-562 cell |
- |
652027, 709955 |
3.4.21.71 | Pancreatic elastase II |
K-562 cell |
- |
718106 |