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Literature summary for 2.3.1.37 extracted from

  • Zhang, F.L.; Shen, G.M.; Liu, X.L.; Wang, F.; Zhao, H.L.; Yu, J.; Zhang, J.W.
    Hypoxic induction of human erythroid-specific sigma-aminolevulinate synthase mediated by hypoxia-inducible factor 1 (2011), Biochemistry, 50, 1194-1202.
    View publication on PubMed
Search for more literature for 2.3.1.37

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
erythroid cell erythroid induction cultures of CD34+ hematopoietic stem/progenitor cells Homo sapiens
-
K-562 cell
-
 Homo sapiens
-

Synonyms

Synonyms Comment Organism
ALAS2
-
 Homo sapiens
sigma-aminolevulinate synthase
-
 Homo sapiens

Expression

Organism Comment Expression
Homo sapiens HIF1R knockdown by RNA interference decreased the level of ALAS2 expression. In silico analysis reveal three potential hypoxia-response elements (HREs) that are located 611, 621, and 741 bp downstream of the ALAS2 gene down
Homo sapiens under hypoxic conditions, significantly increased ALAS2 mRNA and protein levels are detected in K562 cells and erythroid induction cultures of CD34+ hematopoietic stem/progenitor cells up