Information on EC - arsenite methyltransferase

for references in articles please use BRENDA:EC2.1.1.137
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EC Tree
     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
       arsenite methyltransferase
IUBMB Comments
An enzyme of the biotransformation pathway that forms dimethylarsinate from inorganic arsenite and arsenate. It methylates arsenite to form methylarsonate, Me-AsO3H2, which is reduced by EC, methylarsonate reductase, to methylarsonite, Me-As(OH)2. Methylarsonite is also a substrate for this enzyme (EC, which converts it into the much less toxic compound dimethylarsinate (cacodylate), Me2As(O)-OH.
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The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea
AdoMet:arsenic(III) methyltransferase, arsenic (+3 oxidation state) methyltransferase, arsenic (+3 oxidation state)-methyltransferase, arsenic (+3) methyltransferase, arsenic (III) methyltransferase, arsenic (III) S-adenosylmethionine methyltransferase, arsenic methyltransferase Cyt19, arsenic(III) methyltransferase, arsenite (+3 oxidation state) methyltransferase, arsenite methyltransferase, more
S-adenosyl-L-methionine + arsenite = S-adenosyl-L-homocysteine + methylarsonate
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S-adenosyl-L-methionine + methylarsonite = S-adenosyl-L-homocysteine + dimethylarsinate
show the reaction diagram
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