Any feedback?
Please rate this page
(enzyme.php)
(0/150)

BRENDA support

Information on EC 1.10.5.1 - ribosyldihydronicotinamide dehydrogenase (quinone)

for references in articles please use BRENDA:EC1.10.5.1

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
IUBMB Comments

A flavoprotein. Unlike EC 1.6.5.2, NAD(P)H dehydrogenase (quinone), this quinone reductase cannot use NADH or NADPH; instead it uses N-ribosyl- and N-alkyldihydronicotinamides. Polycyclic aromatic hydrocarbons, such as benz[a]anthracene, and the estrogens 17β-estradiol and diethylstilbestrol are potent inhibitors, but dicoumarol is only a very weak inhibitor . This enzyme can catalyse both 2-electron and 4-electron reductions, but one-electron acceptors, such as potassium ferricyanide, cannot be reduced .

The expected taxonomic range for this enzyme is: Bacteria, Eukaryota

Synonyms
quinone reductase 2, nrh:quinone oxidoreductase 2, quinone oxidoreductase 2, quinone reductase type 2, nrh:quinone oxidoreductase, dihydronicotinamide riboside:quinone oxidoreductase, dihydronicotinamide riboside:quinone oxidoreductase 2, dihydronicotinamide riboside:quinone reductase 2, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
1-(beta-D-ribofuranosyl)-1,4-dihydronicotinamide + a quinone = 1-(beta-D-ribofuranosyl)nicotinamide + a quinol
show the reaction diagram
-
-
-
-