Cloned (Comment) | Organism |
---|---|
- |
Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
succinyl-CoA + glycine | Homo sapiens | ALAS2 synthesizes heme specifically for haemoglobin | 5-aminolevulinate + CoA + CO2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Oxidation Stability | Organism |
---|---|
ALAS2 is broken down under normoxic conditions by the proteasome | Homo sapiens |
Posttranslational Modification | Comment | Organism |
---|---|---|
additional information | ALAS2 is hydroxylated under normoxic conditions | Homo sapiens |
ubiquitinylation | ALAS2 appears to be ubiquitinated as rapidly as at is produced | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
K-562 cell | ALAS2 is expressed exclusively in erythroid cells | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
succinyl-CoA + glycine | ALAS2 synthesizes heme specifically for haemoglobin | Homo sapiens | 5-aminolevulinate + CoA + CO2 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ALAS2 | - |
Homo sapiens |