Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.2.1.18 extracted from

  • Ha, K.T.; Lee, Y.C.; Cho, S.H.; Kim, J.K.; Kim, C.H.
    Molecular characterization of membrane type and ganglioside-specific sialidase (Neu3) expressed in E. coli (2004), Mol. Cell, 17, 267-273.
    View publication on PubMed
Search for more literature for 3.2.1.18

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
48000
-
 x * 48000, SDS-PAGE Homo sapiens
48252
-
 x * 48252, calculated from sequence Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
recombinant enzyme Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
K-562 cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4-methylumbelliferyl-alpha-D-N-acetylneuraminic acid + H2O
-
 Homo sapiens 4-methylumbelliferone + N-acetylneuraminic acid
-
 ?

Subunits

Subunits Comment Organism
? x * 48000, SDS-PAGE Homo sapiens
? x * 48252, calculated from sequence Homo sapiens

Synonyms

Synonyms Comment Organism
ganglioside-specific sialidase
-
 Homo sapiens
Neu3
-
 Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
4.5
-
-
 Homo sapiens

pH Range

pH Minimum pH Maximum Comment Organism
3.5 5 pH 3.5: about 30% of maximal activity, pH 5.0: about 60% of maximal activity Homo sapiens