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BRENDA support

Statistics (01.2026)

Increase in the data content of BRENDA in the last years

07.2007
07.2008 - 01.2025
01.2026
Increase from 07.2007 to 01.2026
ACTIVATING COMPOUNDS*
18466
40907
22441 (122%)
APPLICATIONS*
35108
35108
CAS REGISTRY NUMBERS*
4512
4512
CLONED*
79949
79949
COFACTORS*
61915
61915
CRYSTALLIZATIONS*
20793
20793
EC CLASSES
4762
8831
4069 (85%)
ENGINEERING/MUTATIONS*
23234
136161
112927 (486%)
ENZYME SYNONYMS
53389
389057
335668 (629%)
EXPRESSION*
15880
15880
GENERAL INFORMATION*
106345
106345
GENERAL STABILITIES*
9063
9063
IC50 VALUES*
0
80377
80377
INHIBITORS*
112470
325298
212828 (189%)
KCAT/KM VALUES*
44940
44940
KI VALUES*
15736
49409
33673 (214%)
KM VALUES*
79431
186457
107026 (135%)
LIGAND 2D STRUCTURES
38488
177372
138884 (361%)
LIGANDS*
764282
2917069
2152787 (282%)
LOCALIZATION*
19011
74326
55315 (291%)
METALS AND IONS*
72990
72990
NATURAL SUBSTRATES OF ENZYMATIC REACTIONS*
51123
310094
258971 (507%)
ORGANIC SOLVENT STABILITIES*
4214
4214
ORGANISM
16059752
16059752
OXIDATION STABILITIES*
978
978
pH OPTIMA*
61967
61967
pH RANGES*
14036
14036
pH STABILITIES*
9575
9575
pI VALUES*
2060
7869
5809 (282%)
POSTTRANSLATIONAL MODIFICATIONS*
13130
13130
PURIFICATIONS*
70511
70511
REACTION TYPES*
14378
14378
REACTIONS
24355
24355
REFERENCES
68366
176367
108001 (158%)
RENATURED*
1449
1449
SEQUENCES
283138
32832265
32549127 (11496%)
SOURCE TISSUE*
44110
183780
139670 (317%)
SPECIFIC ACTIVITIES*
62289
62289
STORAGE STABILITIES*
11635
11635
SUBSTRATES AND PRODUCTS
566851
566851
SUBUNITS*
80354
80354
TEMPERATURE OPTIMA*
44889
44889
TEMPERATURE RANGES*
7531
7531
TEMPERATURE STABILITIES*
29796
29796
TURNOVER NUMBERS*
94073
94073
* = The numbers denote the enzyme-organism-(protein-)commentary-reference-specific occurrences. For kinetic values (Km, Ki, kcat) and ligand-specific fields (Inhibitors, Activating Compounds, Ligands) the corresponding enzyme ligand is also taken into account.
For example, when the identical pI (isoelectric point) was measured for different enzymes or the identical enzyme from different organisms the information is included for each EC number and organism-specific enzyme isoform, respectively.