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Information on EC 2.3.1.B43 - protein-lysine desuccinylase (NAD+)

for references in articles please use BRENDA:EC2.3.1.B43
preliminary BRENDA-supplied EC number
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The expected taxonomic range for this enzyme is: Archaea, Bacteria, Eukaryota
Synonyms
CobB, CobB Sir2 protein, NAD+-dependent protein deacetylase, NAD+-dependent sirtuin deacetylase, nicotinamide adenine dinucleotide, nicotinamide adenine dinucleotide-dependent protein deacetylase, Sir2Af1, SIRT5, SIRT5iso1, SIRT5iso2, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
NAD+ + [protein]-N6-acetyl-L-lysine = nicotinamide + [protein]-L-lysine + 2'-O-acetyl-ADP-ribose
show the reaction diagram
NAD+ + [protein]-N6-succinyl-L-lysine = nicotinamide + [protein]-L-lysine + 2'-O-succinyl-ADP-ribose
show the reaction diagram
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