Information on EC - malate dehydrogenase

for references in articles please use BRENDA:EC1.1.1.37
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EC Tree
     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
       malate dehydrogenase
IUBMB Comments
There are several forms of malate dehydrogenases that differ by their use of substrate and cofactors. This NAD+-dependent enzyme forms oxaloacetate and unlike EC, malate dehydrogenase (oxaloacetate-decarboxylating), is unable to convert it to pyruvate. Also oxidizes some other 2-hydroxydicarboxylic acids. cf. EC, malate dehydrogenase (NADP+); EC, malate dehydrogenase [NAD(P)+]; and EC, malate dehydrogenase (quinone).
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Word Map
The enzyme appears in viruses and cellular organisms
Reaction Schemes
malate dehydrogenase, mdh, mitochondrial malate dehydrogenase, malic dehydrogenase, cytosolic malate dehydrogenase, maldh, nad-dependent malate dehydrogenase, mitochondrial mdh, s-mdh, l-malate dehydrogenase, more
(S)-malate + NAD+ = oxaloacetate + NADH + H+
show the reaction diagram