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UDP + fragment(1-24) of human basic fibroblast growth factor
UDP + ?
-
-
-
-
?
UDP + human basic fibroblast growth factor
UDP + ?
-
transfer of xylose to the serine residue of the G-S-G-motif in the amino terminal end of human basic fibroblast growth factor
-
-
?
UDP-alpha-D-xylose + [protein]-L-serine
UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine
UDP-alpha-D-xylose + [Smith-degraded chondroitin sulfate proteoglycan]-L-serine
UDP + [Smith-degraded chondroitin sulfate proteoglycan]-3-O-(beta-D-xylosyl)-L-serine
-
-
-
-
?
UDP-D-xylose + aggrecan
UDP + ?
-
-
-
-
?
UDP-D-xylose + bamcan
UDP + ?
-
-
-
-
?
UDP-D-xylose + betaglycan-1
UDP + ?
-
-
-
-
?
UDP-D-xylose + bFGF-peptide
UDP + ?
-
-
-
-
?
UDP-D-xylose + biglycan
UDP + D-xylosyl-biglycan
UDP-D-xylose + biglycan
UDP + xylosyl-biglycan
-
-
-
?
UDP-D-xylose + bikunin
UDP + ?
UDP-D-xylose + bikunin
UDP + D-xylosyl-bikunin
UDP-D-xylose + bikunin-derived aminoterminus homologous peptide
UDP + xylosyl-serine bikunin-derived aminoterminus homologous peptide
-
-
-
?
UDP-D-xylose + biotin-NH-QEEEGSGGGQKK(5-fluorescein)-CONH2
UDP + biotin-NH-QEEEG-(D-xylosyl)SGGGQKK(5-fluorescein)-CONH2
UDP-D-xylose + biotin-NH-QEEEGSGGGQKK(5-fluorescein)-CONH2
UDP + biotin-NH-QEEEGS(D-xylosyl)GGGQKK(5-fluorescein)-CONH2
best substrate known so far for XT-IImediated xylosylation
-
-
?
UDP-D-xylose + biotin-NHQEEEGSGGGQKK(5-fluorescein)-CONH2
UDP + biotin-NHQEEEG-(D-xylosyl)SGGGQKK(5-fluorescein)-CONH2
UDP-D-xylose + cartilage chondroitin sulfate proteoglycan
UDP + cartilage chondroitin sulfate proteoglycan with xylosylserine
UDP-D-xylose + cartilage proteoglycan
UDP + cartilage proteoglycan with xylosylserine
UDP-D-xylose + CD44
UDP + ?
-
-
-
-
?
UDP-D-xylose + CDEASGIGPDDRD
UDP + ?
-
-
-
-
?
UDP-D-xylose + CDEASGIGPEVPDDRD
UDP + CDEAS(-D-xylose)GIGPEVPDDRD
-
synthetic peptide
-
-
?
UDP-D-xylose + collagen alpha2(IX)
UDP + ?
-
-
-
-
?
UDP-D-xylose + DDDSIEGSGGR
UDP + ?
Drosophila sp. (in: flies)
-
-
-
-
?
UDP-D-xylose + DDDSIEGSGGR
UDP + DDDSIEG(D-xylosyl)SGGR
UDP-D-xylose + DDDSIEGSGSGGR
UDP + DDD-(D-xylosyl)SIEGSGSGGR
UDP-D-xylose + decorin (PG40) peptide
UDP + ?
-
-
-
-
?
UDP-D-xylose + DSISGDDLGSGDLGSGDFQR
?
UDP-D-xylose + DSISGDDLGSGDLGSGDFQR
UDP + ?
-
-
-
?
UDP-D-xylose + epidermal growth factor-like protein
UDP + epidermal growth factor-like protein with beta-D-xylosylserine
-
-
-
-
?
UDP-D-xylose + fibroblast growth factor 2
?
-
-
-
?
UDP-D-xylose + fibroblast growth factor 2 fragment 1-24
?
-
-
-
?
UDP-D-xylose + fibroblast growth factor 2 peptide
?
-
-
-
?
UDP-D-xylose + FMLEDEASGIGP
UDP + FMLEDEAS(-D-xylose)GIGP
-
synthetic peptide
-
-
?
UDP-D-xylose + Gln-Ser-Gly
UDP + Gln-(O-D-xylosyl)-Ser-Gly
-
-
-
-
?
UDP-D-xylose + Gly-Ser-Gly
UDP + Gly-(O-D-xylosyl)Ser-Gly
-
-
-
-
?
UDP-D-xylose + Gly-Ser-Gly-Ser-Gly-Ser-Gly-Ser-Gly-Ser
UDP + ?
-
-
-
-
?
UDP-D-xylose + Gly-Thr-Gly
UDP + Gly-(O-D-xylosyl)-Thr-Gly
-
-
-
-
?
UDP-D-xylose + glypican-1
UDP + ?
-
-
-
-
?
UDP-D-xylose + GVEGSADFLK
UDP + GVEGS(-D-xylose)ADFLK
-
derived from collagen X
-
?
UDP-D-xylose + HF-degraded chondroitin sulfate proteoglycan
UDP + ?
UDP-D-xylose + KKDSGPY
UDP + KKDS(-D-xylose)GPY
-
-
-
?
UDP-D-xylose + KTKGSGFFVF
UDP + KTKGS(-D-xylose)GFFVF
-
-
-
?
UDP-D-xylose + L-APLP2
UDP + ?
-
-
-
-
?
UDP-D-xylose + L-APP
UDP + ?
-
-
-
-
?
UDP-D-xylose + neuroglycan C
UDP + ?
-
-
-
-
?
UDP-D-xylose + NFDEIDRSGFGFN
UDP + NFDEIDRS(-D-xylose)GFGFN
-
-
-
?
UDP-D-xylose + perlecan-1
UDP + ?
-
-
-
-
?
UDP-D-xylose + perlecan-2
UDP + ?
-
-
-
-
?
UDP-D-xylose + perlecan-3
UDP + ?
-
-
-
-
?
UDP-D-xylose + phosphacan
UDP + ?
-
-
-
-
?
UDP-D-xylose + PLVSSGEDEPK
UDP + ?
-
derived from neurocan protein
D-xylose bound to a serine residue
?
UDP-D-xylose + proteoglycan core protein
UDP + proteoglycan core protein with xyloserine
the xylosyltransferases I and II catalyze the transfer of xylose from UDP-xylose to selected serine residues in the proteoglycan core protein, which is the initial and rate limiting step in glycosaminoglycan biosynthesis
-
-
?
UDP-D-xylose + proteoglycan core protein
UDP + proteoglycan core protein with xylosylserine
the xylosyltransferases I and II catalyze the transfer of xylose from UDP-xylose to selected serine residues in the proteoglycan core protein, which is the initial and rate limiting step in glycosaminoglycan biosynthesis
-
-
?
UDP-D-xylose + QEEEGSGGGGQR
UDP + QEEEG(-D-xylosyl)SGGGGQR
-
-
-
?
UDP-D-xylose + QEEEGSGGGGQR
UDP + QEEEG(D-xylosyl)SGGGGQR
UDP-D-xylose + QEEEGSGGGGQR
UDP + QEEEG-(D-xylosyl)-S-GGGGQR
-
-
-
?
UDP-D-xylose + QEEEGSGGGOK
UDP + QEEEGS(-D-xylose)GGGOK
UDP-D-xylose + QEEEGSGGGQGG
UDP + ?
-
bikunin-type peptide
-
-
?
UDP-D-xylose + QEEEGSGGGQGG
UDP + QEEEGS(-D-xylose)GGGQGG
-
peptide derived from bikunin
-
?
UDP-D-xylose + QEEEGSGGGQK
UDP + ?
-
-
-
-
?
UDP-D-xylose + QEEEGSGGGQKK
UDP + QEEEG-(D-xylosyl)SGGGQKK
UDP-D-xylose + QEEEGSGGGQKK
UDP + QEEEGS(-D-xylose)GGGQKK
-
peptide derived from bikunin
-
?
UDP-D-xylose + QEEEGTGGGQGG
UDP + ?
-
-
-
-
?
UDP-D-xylose + QGGGGSGGGQGG
UDP + ?
-
-
-
-
?
UDP-D-xylose + rat L2 chondroitin sulfate
UDP + ?
-
-
-
-
?
UDP-D-xylose + SAAYSGSGSG
UDP + ?
-
-
-
-
?
UDP-D-xylose + SDDYSGSGSG
UDP + ?
-
-
-
-
?
UDP-D-xylose + SDDYSGSGSG
UDP + SDDYS(-D-xylose)GSGSG
-
synthetic peptide
-
-
?
UDP-D-xylose + SENEGSGMAEQK
UDP + SENEGS(-D-xylose)GMAEQK
-
synthetic leukocyte-derived amyloid precursor-like protein homologous peptide
-
?
UDP-D-xylose + SENEGSGMAQQK
UDP + ?
-
-
-
-
?
UDP-D-xylose + Ser-Gly-Ala-Gly-Ala-Gly
UDP + xylosyl-Ser-Gly-Ala-Gly-Ala-Gly
-
silk sequence hexapeptide
-
-
?
UDP-D-xylose + Ser-Gly-Gly
UDP + O-D-xylosyl-Ser-Gly-Gly
-
-
-
-
?
UDP-D-xylose + serglycin
UDP + ?
-
-
-
-
?
UDP-D-xylose + SIEGSGGR
UDP + (D-xylosyl)SIEGSGGR
-
-
-
?
UDP-D-xylose + SIEGSGGR
UDP + D-xylosyl-SIEGSGGR
-
-
-
?
UDP-D-xylose + SIEGSGGR
UDP + SIEG(D-xylosyl)SGGR
-
-
-
-
?
UDP-D-xylose + silk fibroin
?
-
-
-
?
UDP-D-xylose + silk fibroin
UDP + ?
-
-
-
-
?
UDP-D-xylose + silk fibroin
UDP + silk fibroin with xylosylserine
UDP-D-xylose + Smith-degraded chondroitin sulfate proteoglycan
UDP + ?
UDP-D-xylose + syndecan
UDP + ?
-
-
-
-
?
UDP-D-xylose + syndecan-1
UDP + ?
-
-
-
-
?
UDP-D-xylose + syndecan-4
UDP + ?
-
-
-
-
?
UDP-D-xylose + TENEGSGLTNIK
UDP + ?
-
-
-
-
?
UDP-D-xylose + TENEGSGLTNIK
UDP + TENEG-(D-xylosyl)SGLTNIK
UDP-D-xylose + TENEGSGLTNIK
UDP + TENEGS(-D-xylose)GLTNIK
-
synthetic leukocyte-derived beta-A4-amyloid protein precursor homologous peptide
-
?
UDP-D-xylose + testican-2
UDP + ?
-
-
-
-
?
UDP-D-xylose + thrombomodulin
UDP + ?
-
-
-
-
?
UDP-D-xylose + VCRSGSGLVGK
UDP + VCRSGSGLVGK
-
derived from apolipoprotein J
D-xylose bound to a serine residue
?
UDP-D-xylose + versican-beta
UDP + ?
-
-
-
-
?
UDP-D-xylose + WAGGDASGE
UDP + WAGGDAS(-D-xylose)GE
-
-
-
?
UDP-D-xylose + [Val36,Val38]delta1[Gly92,Ile94]delta2bikunin
UDP + ?
-
-
-
-
?
additional information
?
-
UDP-alpha-D-xylose + [protein]-L-serine
UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine
-
-
-
?
UDP-alpha-D-xylose + [protein]-L-serine
UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine
-
-
-
-
?
UDP-alpha-D-xylose + [protein]-L-serine
UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine
-
exogenous protein acceptor obtained by Smith degradation of bovine chondroitin sulfate-protein complex
-
-
?
UDP-alpha-D-xylose + [protein]-L-serine
UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine
-
transfers a beta-D-xylosyl residue from UDP-D-xylose to the serine hydroxyl group of an acceptor protein substrate
-
-
?
UDP-alpha-D-xylose + [protein]-L-serine
UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine
-
tryptic and chymotryptic fragments from fibroin
-
-
?
UDP-alpha-D-xylose + [protein]-L-serine
UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine
-
transfers a beta-D-xylosyl residue from UDP-D-xylose to the serine hydroxyl group of an acceptor protein substrate
-
?
UDP-alpha-D-xylose + [protein]-L-serine
UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine
-
transfers a beta-D-xylosyl residue from UDP-D-xylose to the serine hydroxyl group of an acceptor protein substrate
-
?
UDP-alpha-D-xylose + [protein]-L-serine
UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine
-
transfers a beta-D-xylosyl residue from UDP-D-xylose to the serine hydroxyl group of an acceptor protein substrate
-
?
UDP-alpha-D-xylose + [protein]-L-serine
UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine
-
transfers a beta-D-xylosyl residue from UDP-D-xylose to the serine hydroxyl group of an acceptor protein substrate
-
?
UDP-alpha-D-xylose + [protein]-L-serine
UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine
-
transfers a beta-D-xylosyl residue from UDP-D-xylose to the serine hydroxyl group of an acceptor protein substrate
-
?
UDP-alpha-D-xylose + [protein]-L-serine
UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine
-
transfers a beta-D-xylosyl residue from UDP-D-xylose to the serine hydroxyl group of an acceptor protein substrate
-
?
UDP-alpha-D-xylose + [protein]-L-serine
UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine
-
transfers a beta-D-xylosyl residue from UDP-D-xylose to the serine hydroxyl group of an acceptor protein substrate
-
?
UDP-alpha-D-xylose + [protein]-L-serine
UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine
-
transfers a beta-D-xylosyl residue to specific serine residues dependent on the consensus signal sequence
-
?
UDP-alpha-D-xylose + [protein]-L-serine
UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine
-
transfers a beta-D-xylosyl residue to specific serine residues dependent on the consensus signal sequence
-
?
UDP-alpha-D-xylose + [protein]-L-serine
UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine
-
initiation of chondroitin sulfate biosynthesis
-
-
?
UDP-alpha-D-xylose + [protein]-L-serine
UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine
-
enzyme may play a role in maintaining the haemostatic potential of the follicular fluid
-
-
?
UDP-alpha-D-xylose + [protein]-L-serine
UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine
-
enzyme is associated with large chondroitin sulfate-containing proteoglycans
-
-
?
UDP-alpha-D-xylose + [protein]-L-serine
UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine
-
enzyme initiates the biosynthesis of glycosaminoglycan lateral chains in proteoglycans by transfer of xylose from UDP-xylose to specific serine residues of the core protein
-
-
?
UDP-alpha-D-xylose + [protein]-L-serine
UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine
-
initiates the biosynthesis of the glycosaminoglycan linkage region
-
-
?
UDP-alpha-D-xylose + [protein]-L-serine
UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine
-
Rumi transfers D-xylose or D-glucose to serine 52 in the O-glucose consensus sequence (50CASSPC55) of factor VII EGF repeat. The second serine (S53) facilitates transfer of Xyl, but not glucose, to the EGF repeat by Rumi. EGF16 of mouse Notch2, which has a diserine motif in the consensus sequence (587CYSSPC592), is also modified with either O-Xyl or O-glucose glycans in cells
-
-
?
UDP-alpha-D-xylose + [protein]-L-serine
UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine
-
-
-
-
?
UDP-alpha-D-xylose + [protein]-L-serine
UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine
-
transfers a beta-D-xylosyl residue from UDP-D-xylose to the serine hydroxyl group of an acceptor protein substrate
-
?
UDP-alpha-D-xylose + [protein]-L-serine
UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine
-
Rumi transfers D-xylose or D-glucose to serine 52 in the O-glucose consensus sequence (50CASSPC55) of factor VII EGF repeat. The second serine (S53) facilitates transfer of Xyl, but not glucose, to the EGF repeat by Rumi. EGF16 of mouse Notch2, which has a diserine motif in the consensus sequence (587CYSSPC592), is also modified with either O-Xyl or O-glucose glycans in cells
-
-
?
UDP-alpha-D-xylose + [protein]-L-serine
UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine
-
-
-
-
?
UDP-alpha-D-xylose + [protein]-L-serine
UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine
-
transfers a beta-D-xylosyl residue from UDP-D-xylose to the serine hydroxyl group of an acceptor protein substrate
-
-
?
UDP-alpha-D-xylose + [protein]-L-serine
UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine
-
transfers a beta-D-xylosyl residue from UDP-D-xylose to the serine hydroxyl group of an acceptor protein substrate
-
?
UDP-alpha-D-xylose + [protein]-L-serine
UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine
-
transfers a beta-D-xylosyl residue from UDP-D-xylose to the serine hydroxyl group of an acceptor protein substrate
-
?
UDP-alpha-D-xylose + [protein]-L-serine
UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine
-
transfers a beta-D-xylosyl residue from UDP-D-xylose to the serine hydroxyl group of an acceptor protein substrate
-
?
UDP-alpha-D-xylose + [protein]-L-serine
UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine
-
transfers a beta-D-xylosyl residue from UDP-D-xylose to the serine hydroxyl group of an acceptor protein substrate
-
?
UDP-alpha-D-xylose + [protein]-L-serine
UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine
-
transfers a beta-D-xylosyl residue to specific serine residues dependent on the consensus signal sequence
-
?
UDP-alpha-D-xylose + [protein]-L-serine
UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine
-
transfers a beta-D-xylosyl residue to specific serine residues dependent on the consensus signal sequence
-
?
UDP-alpha-D-xylose + [protein]-L-serine
UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine
-
transfers a beta-D-xylosyl residue from UDP-D-xylose to the serine hydroxyl group of an acceptor protein substrate
-
?
UDP-alpha-D-xylose + [protein]-L-serine
UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine
-
transfers a beta-D-xylosyl residue to specific serine residues dependent on the consensus signal sequence
-
?
UDP-D-xylose + biglycan
UDP + D-xylosyl-biglycan
-
-
-
-
?
UDP-D-xylose + biglycan
UDP + D-xylosyl-biglycan
-
-
-
?
UDP-D-xylose + bikunin
?
-
-
-
-
?
UDP-D-xylose + bikunin
?
-
-
-
?
UDP-D-xylose + bikunin
UDP + ?
-
-
-
-
?
UDP-D-xylose + bikunin
UDP + ?
-
-
-
-
?
UDP-D-xylose + bikunin
UDP + ?
-
-
-
?
UDP-D-xylose + bikunin
UDP + D-xylosyl-bikunin
-
-
-
-
?
UDP-D-xylose + bikunin
UDP + D-xylosyl-bikunin
-
-
-
?
UDP-D-xylose + bikunin
UDP + D-xylosyl-bikunin
-
-
-
?
UDP-D-xylose + bikunin
UDP + D-xylosyl-bikunin
-
-
-
?
UDP-D-xylose + bikunin
UDP + D-xylosyl-bikunin
-
-
-
?
UDP-D-xylose + bikunin
UDP + D-xylosyl-bikunin
-
-
-
?
UDP-D-xylose + bikunin
UDP + D-xylosyl-bikunin
-
-
-
?
UDP-D-xylose + bikunin
UDP + D-xylosyl-bikunin
-
recombinant bikunin
bound to serine residue
?
UDP-D-xylose + bikunin
UDP + D-xylosyl-bikunin
-
recombinant wild-type from Chang liver hepatocytes and mutant, expressed in Escherichia coli
bound to serine residue
?
UDP-D-xylose + bikunin
UDP + D-xylosyl-bikunin
-
recombinant mutant bikunin
bound to serine residue
?
UDP-D-xylose + bikunin
UDP + D-xylosyl-bikunin
-
recombinant mutant bikunin
bound to serine residue
?
UDP-D-xylose + bikunin
UDP + D-xylosyl-bikunin
-
recombinant mutant bikunin
-
?
UDP-D-xylose + bikunin
UDP + D-xylosyl-bikunin
-
recombinant mutant bikunin
-
?
UDP-D-xylose + biotin-NH-QEEEGSGGGQKK(5-fluorescein)-CONH2
UDP + biotin-NH-QEEEG-(D-xylosyl)SGGGQKK(5-fluorescein)-CONH2
the bikunin-homologous peptide Bio-QEEEGSGGGQKK-F is best acceptor substrate for XT-II, 100% activity with UDP-D-xylose
-
-
?
UDP-D-xylose + biotin-NH-QEEEGSGGGQKK(5-fluorescein)-CONH2
UDP + biotin-NH-QEEEG-(D-xylosyl)SGGGQKK(5-fluorescein)-CONH2
-
catalytic efficiency of XylT-I is more than 2.4fold higher than for XylT-II
-
-
?
UDP-D-xylose + biotin-NHQEEEGSGGGQKK(5-fluorescein)-CONH2
UDP + biotin-NHQEEEG-(D-xylosyl)SGGGQKK(5-fluorescein)-CONH2
-
-
-
?
UDP-D-xylose + biotin-NHQEEEGSGGGQKK(5-fluorescein)-CONH2
UDP + biotin-NHQEEEG-(D-xylosyl)SGGGQKK(5-fluorescein)-CONH2
-
-
-
?
UDP-D-xylose + biotin-NHQEEEGSGGGQKK(5-fluorescein)-CONH2
UDP + biotin-NHQEEEG-(D-xylosyl)SGGGQKK(5-fluorescein)-CONH2
biotin-NHQEEEGSGGGQKK(5-fluorescein)-CONH2is the best acceptor for isozyme XT-II
-
-
?
UDP-D-xylose + biotin-NHQEEEGSGGGQKK(5-fluorescein)-CONH2
UDP + biotin-NHQEEEG-(D-xylosyl)SGGGQKK(5-fluorescein)-CONH2
biotin-NHQEEEGSGGGQKK(5-fluorescein)-CONH2is the best acceptor for isozyme XT-II
-
-
?
UDP-D-xylose + cartilage chondroitin sulfate proteoglycan
UDP + cartilage chondroitin sulfate proteoglycan with xylosylserine
-
degraded by hydrogen fluoride or trifluromethanesulfonic acid
-
-
?
UDP-D-xylose + cartilage chondroitin sulfate proteoglycan
UDP + cartilage chondroitin sulfate proteoglycan with xylosylserine
-
HF-deglycosylated acceptor
-
-
?
UDP-D-xylose + cartilage chondroitin sulfate proteoglycan
UDP + cartilage chondroitin sulfate proteoglycan with xylosylserine
-
the consensus sequence, acidic-acidic-Xxx-Ser-Gly-Xxx-Gly, in the acceptor proteoglycan is important
-
-
?
UDP-D-xylose + cartilage chondroitin sulfate proteoglycan
UDP + cartilage chondroitin sulfate proteoglycan with xylosylserine
-
deglycosylation by Staphylococcus aureus V8 protease decreases the activity with the resulting peptides
-
-
?
UDP-D-xylose + cartilage proteoglycan
UDP + cartilage proteoglycan with xylosylserine
-
Smith-degraded or HF-treated
-
-
?
UDP-D-xylose + cartilage proteoglycan
UDP + cartilage proteoglycan with xylosylserine
-
modified substrate degradation method
-
-
?
UDP-D-xylose + DDDSIEGSGGR
UDP + DDDSIEG(D-xylosyl)SGGR
-
-
-
?
UDP-D-xylose + DDDSIEGSGGR
UDP + DDDSIEG(D-xylosyl)SGGR
syndecan peptide substrate
-
-
?
UDP-D-xylose + DDDSIEGSGSGGR
UDP + DDD-(D-xylosyl)SIEGSGSGGR
-
-
-
?
UDP-D-xylose + DDDSIEGSGSGGR
UDP + DDD-(D-xylosyl)SIEGSGSGGR
-
-
-
-
?
UDP-D-xylose + DDDSIEGSGSGGR
UDP + DDD-(D-xylosyl)SIEGSGSGGR
-
-
-
?
UDP-D-xylose + DSISGDDLGSGDLGSGDFQR
?
-
the enzyme modifies the peptide with up to two xylose residues
-
-
?
UDP-D-xylose + DSISGDDLGSGDLGSGDFQR
?
-
-
-
?
UDP-D-xylose + DSISGDDLGSGDLGSGDFQR
?
the enzyme modifies the peptide with up to two xylose residues
-
-
?
UDP-D-xylose + HF-degraded chondroitin sulfate proteoglycan
UDP + ?
-
-
-
-
?
UDP-D-xylose + HF-degraded chondroitin sulfate proteoglycan
UDP + ?
-
-
-
-
?
UDP-D-xylose + QEEEGSGGGGQR
UDP + QEEEG(D-xylosyl)SGGGGQR
-
-
-
-
?
UDP-D-xylose + QEEEGSGGGGQR
UDP + QEEEG(D-xylosyl)SGGGGQR
-
-
-
?
UDP-D-xylose + QEEEGSGGGOK
UDP + QEEEGS(-D-xylose)GGGOK
-
best substrate
-
?
UDP-D-xylose + QEEEGSGGGOK
UDP + QEEEGS(-D-xylose)GGGOK
-
peptide derived from bikunin
-
?
UDP-D-xylose + QEEEGSGGGQKK
UDP + QEEEG-(D-xylosyl)SGGGQKK
-
the bikunin nuclear acceptor peptide QEEEGSGGGQKK is not a differential acceptor substrate for the human XylT isoenzymes but is a good acceptor substrate for total XylT activity measurements
-
-
?
UDP-D-xylose + QEEEGSGGGQKK
UDP + QEEEG-(D-xylosyl)SGGGQKK
-
QEEEGSGGGQKK is a better acceptor substrate than TENEGSGLTNIK
-
-
?
UDP-D-xylose + silk fibroin
UDP + silk fibroin with xylosylserine
-
-
-
?
UDP-D-xylose + silk fibroin
UDP + silk fibroin with xylosylserine
-
-
-
?
UDP-D-xylose + silk fibroin
UDP + silk fibroin with xylosylserine
-
acceptor substrate from Bombyx mori consists in large part of the repeating hexapeptide: Ser-Gly-Ala-Gly-Ala-Gly
-
-
?
UDP-D-xylose + silk fibroin
UDP + silk fibroin with xylosylserine
-
-
-
-
?
UDP-D-xylose + silk fibroin
UDP + silk fibroin with xylosylserine
-
-
-
?
UDP-D-xylose + silk fibroin
UDP + silk fibroin with xylosylserine
-
-
-
?
UDP-D-xylose + silk fibroin
UDP + silk fibroin with xylosylserine
-
acceptor substrate contains repetitive sequence Gly-Ser-Gly-Ala-Gly-Ala
-
-
?
UDP-D-xylose + silk fibroin
UDP + silk fibroin with xylosylserine
silk fibroin is a low affinity acceptor for XT-II
-
-
?
UDP-D-xylose + silk fibroin
UDP + silk fibroin with xylosylserine
-
-
-
?
UDP-D-xylose + Smith-degraded chondroitin sulfate proteoglycan
UDP + ?
-
-
-
-
?
UDP-D-xylose + Smith-degraded chondroitin sulfate proteoglycan
UDP + ?
-
-
-
-
?
UDP-D-xylose + TENEGSGLTNIK
UDP + TENEG-(D-xylosyl)SGLTNIK
-
the 3-A4-amyloid protein precursor protein peptide TENEGSGLTNIK is an acceptor substrate for XylT1
-
-
?
UDP-D-xylose + TENEGSGLTNIK
UDP + TENEG-(D-xylosyl)SGLTNIK
-
QEEEGSGGGQKK is a better acceptor substrate than TENEGSGLTNIK
-
-
?
additional information
?
-
synthesis of chondrioitin and heparan sulphates is initiated by UDP-alpha-D-xylose:proteoglycan core protein beta-D-xylosyltransferase
-
-
?
additional information
?
-
-
synthesis of chondrioitin and heparan sulphates is initiated by UDP-alpha-D-xylose:proteoglycan core protein beta-D-xylosyltransferase
-
-
?
additional information
?
-
-
synthesis of chondrioitin and heparan sulphates is initiated by UDP-alpha-D-xylose:proteoglycan core protein beta-D-xylosyltransferase
-
-
?
additional information
?
-
-
the enzyme is also able to use UDP-glucose as donor substrate
-
-
?
additional information
?
-
-
substrate preparation and specificity
-
-
?
additional information
?
-
-
involved in the biosynthesis of the linkage region of proteochondroitin sulfate
-
-
?
additional information
?
-
-
tripeptide SGG is a poor substrate
-
-
?
additional information
?
-
-
very low activity with tripeptide SGG and peptide LNFSTGW
-
-
?
additional information
?
-
-
enzyme activity in seminal plasma of infertile men is significantly reduced
-
-
?
additional information
?
-
first enzyme required for the generation of chondroitin and heparan sulfate glycosaminoglycan chains of proteoglycans
-
-
?
additional information
?
-
first enzyme required for the generation of chondroitin and heparan sulfate glycosaminoglycan chains of proteoglycans
-
-
?
additional information
?
-
-
first enzyme required for the generation of chondroitin and heparan sulfate glycosaminoglycan chains of proteoglycans
-
-
?
additional information
?
-
synthesis of chondrioitin and heparan sulphates is initiated by UDP-alpha-D-xylose:proteoglycan core protein beta-D-xylosyltransferase
-
-
?
additional information
?
-
-
synthesis of chondrioitin and heparan sulphates is initiated by UDP-alpha-D-xylose:proteoglycan core protein beta-D-xylosyltransferase
-
-
?
additional information
?
-
-
xylosyltransferase II is involved in the biosynthesis of the uniform tetrasaccharide linkage region in chondroitin sulfate and heparan sulfate proteoglycans
-
-
?
additional information
?
-
xylosyltransferase II is involved in the biosynthesis of the uniform tetrasaccharide linkage region in chondroitin sulfate and heparan sulfate proteoglycans
-
-
?
additional information
?
-
-
XT-II initiates the biosynthesis of both heparan sulfate and chondroitin sulfate
-
-
?
additional information
?
-
XT-II initiates the biosynthesis of both heparan sulfate and chondroitin sulfate
-
-
?
additional information
?
-
TENEGSGLTNIK, SENEGSGMAEQK, orcokinin (NFDEIDRSGFGFN), melittin (GIGAVLKVLTTGLPALISWIKRKRQQ), fibrinopeptide A (ADSGEGDFLAEGGGVR), IgE C4 domain (KTKGSGFFVF), C-type natriuretic peptide (GLSKGCFGLKLDRIGSMSGLGC), and calcitonin (VLGKLSQELHKLQTYPRTNTGSGTP) are no substrates for XT-II
-
-
?
additional information
?
-
-
TENEGSGLTNIK, SENEGSGMAEQK, orcokinin (NFDEIDRSGFGFN), melittin (GIGAVLKVLTTGLPALISWIKRKRQQ), fibrinopeptide A (ADSGEGDFLAEGGGVR), IgE C4 domain (KTKGSGFFVF), C-type natriuretic peptide (GLSKGCFGLKLDRIGSMSGLGC), and calcitonin (VLGKLSQELHKLQTYPRTNTGSGTP) are no substrates for XT-II
-
-
?
additional information
?
-
-
-
-
-
?
additional information
?
-
-
substrate specificity
-
-
?
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Adenoma, Pleomorphic
The relationship between proteoglycan inhibition via xylosyltransferase II silencing and the implantation of salivary pleomorphic adenoma.
Astrocytoma
Circulating microRNAs as Biomarkers for Pediatric Astrocytomas.
Cardiomyopathy, Dilated
Transforming growth factor beta1-regulated xylosyltransferase I activity in human cardiac fibroblasts and its impact for myocardial remodeling.
Cataract
Abnormal Proteoglycan Synthesis Due to Gene Defects Causes Skeletal Diseases with Overlapping Phenotypes.
Cataract
Corneal clouding, cataract, and colobomas with a novel missense mutation in B4GALT7-a review of eye anomalies in the linkeropathy syndromes.
Cataract
Homozygosity for frameshift mutations in XYLT2 result in a spondylo-ocular syndrome with bone fragility, cataracts, and hearing defects.
Cataract
Spondyloocular Syndrome - Novel Mutations in XYLT2 Gene and Expansion of the Phenotypic Spectrum.
Cysts
Polycystic disease caused by deficiency in xylosyltransferase 2, an initiating enzyme of glycosaminoglycan biosynthesis.
Diabetes Complications
Identification of a xylosyltransferase II gene haplotype marker for diabetic nephropathy in type 1 diabetes.
Diabetes Mellitus, Type 1
Identification of a xylosyltransferase II gene haplotype marker for diabetic nephropathy in type 1 diabetes.
Diabetes Mellitus, Type 1
Impact of polymorphisms in the genes encoding xylosyltransferase I and a homologue in type 1 diabetic patients with and without nephropathy.
Diabetes Mellitus, Type 1
Novel sequence variants in the human xylosyltransferase I gene and their role in diabetic nephropathy.
Diabetic Nephropathies
Human xylosyltransferases in health and disease.
Diabetic Nephropathies
Identification of a xylosyltransferase II gene haplotype marker for diabetic nephropathy in type 1 diabetes.
Diabetic Nephropathies
The Xylosyltransferase I Gene Polymorphism c.343G>T (p.A125S) Is a Risk Factor for Diabetic Nephropathy in Type 1 Diabetes.
Essential Hypertension
Xylosyltransferase gene variants and their role in essential hypertension.
Glaucoma
Corneal clouding, cataract, and colobomas with a novel missense mutation in B4GALT7-a review of eye anomalies in the linkeropathy syndromes.
Hearing Loss
Abnormal Proteoglycan Synthesis Due to Gene Defects Causes Skeletal Diseases with Overlapping Phenotypes.
Hearing Loss
Spondyloocular Syndrome - Novel Mutations in XYLT2 Gene and Expansion of the Phenotypic Spectrum.
Hearing Loss, Sensorineural
Homozygosity for frameshift mutations in XYLT2 result in a spondylo-ocular syndrome with bone fragility, cataracts, and hearing defects.
Infections
Hepatitis C virus infection propagates through interactions between Syndecan-1 and CD81 and impacts the hepatocyte glycocalyx.
Infections
Sulfonated azo dyes enhance the genome release of enterovirus A71 VP1-98K variants by preventing the virions from being trapped by sulfated glycosaminoglycans at acidic pH.
Joint Diseases
UDP-D-xylose: proteoglycan core protein beta-D-xylosyltransferase: a new marker of cartilage destruction in chronic joint diseases.
Kidney Diseases
Polycystic disease caused by deficiency in xylosyltransferase 2, an initiating enzyme of glycosaminoglycan biosynthesis.
Lipodystrophy
Adipose tissue loss and lipodystrophy in xylosyltransferase II deficient mice.
Mastocytoma
Glycosylation of serine residues by a uridine diphosphate-xylose: protein xylosyltransferase from mouse mastocytoma.
Mucopolysaccharidosis III
Impairment of glycosaminoglycan synthesis in mucopolysaccharidosis type IIIA cells by using siRNA: a potential therapeutic approach for Sanfilippo disease.
Neoplasms
The relationship between proteoglycan inhibition via xylosyltransferase II silencing and the implantation of salivary pleomorphic adenoma.
Neoplasms
Xylosyltransferase II is a significant contributor of circulating xylosyltransferase levels and platelets constitute an important source of xylosyltransferase in serum.
Osteoarthritis
Human xylosyltransferases in health and disease.
Osteoarthritis
Serum xylosyltransferase 1 level increases during early posttraumatic osteoarthritis in mice with high bone forming potential.
Osteoporosis
Abnormal Proteoglycan Synthesis Due to Gene Defects Causes Skeletal Diseases with Overlapping Phenotypes.
Osteoporosis
Recent Discoveries in Monogenic Disorders of Childhood Bone Fragility.
Osteoporosis
Spondyloocular Syndrome - Novel Mutations in XYLT2 Gene and Expansion of the Phenotypic Spectrum.
protein xylosyltransferase deficiency
Homozygosity for frameshift mutations in XYLT2 result in a spondylo-ocular syndrome with bone fragility, cataracts, and hearing defects.
protein xylosyltransferase deficiency
Xylosyltransferase 2 deficiency and organ homeostasis.
Pseudoxanthoma Elasticum
Human xylosyltransferases in health and disease.
Refractive Errors
Corneal clouding, cataract, and colobomas with a novel missense mutation in B4GALT7-a review of eye anomalies in the linkeropathy syndromes.
Retinal Detachment
Corneal clouding, cataract, and colobomas with a novel missense mutation in B4GALT7-a review of eye anomalies in the linkeropathy syndromes.
Stomach Neoplasms
Glucoside xylosyltransferase 2 as a diagnostic and prognostic marker in gastric cancer via comprehensive analysis.
Strabismus
Corneal clouding, cataract, and colobomas with a novel missense mutation in B4GALT7-a review of eye anomalies in the linkeropathy syndromes.
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0.0188
Aggrecan
-
isoenzyme XT-I
-
0.0208
betaglycan-1
-
isoenzyme XT-I
-
0.0093 - 0.0137
bFGF-peptide
-
0.0097
biglycan
-
isoenzyme XT-I
-
0.0006 - 0.0656
bikunin
-
0.022
bikunin-derived aminoterminus homologous peptide
-
-
-
0.0019
Bio-QEEEGSGGGQKK-F
-
0.0025 - 0.0061
biotin-NH-QEEEGSGGGQKK(5-fluorescein)-CONH2
0.0052
biotin-NHQEEEGSGGGQKK(5-fluorescein)-CONH2
recombinant enzyme
0.11 - 0.19
cartilage chondroitin sulfate proteoglycan
-
0.0146
CD44
-
isoenzyme XT-I
-
0.062
CDEASGIGPEVPDDRD
-
-
0.0034
collagen alpha2(IX)
-
isoenzyme XT-I
-
0.5
DDDSIEGSGGR
Drosophila sp. (in: flies)
-
-
0.037
decorin (PG40) peptide
-
-
-
0.062
fibroblast growth factor 2
recombinant enzyme
-
0.0191
fibroblast growth factor 2 fragment 1-24
-
-
0.0208 - 0.0223
fragment(1-24) of human basic fibroblast growth factor
-
0.04
Gly-Ser-Gly-Ser-Gly-Ser-Gly-Ser-Gly-Ser
-
0.2 mM in terms of Ser
0.0109 - 0.0171
glypican-1
-
0.00011 - 1.02
HF-degraded chondroitin sulfate proteoglycan
-
0.0572
human basic fibroblast growth factor
-
native XT-I
-
0.0032 - 0.0236
neuroglycan C
-
0.0133
perlecan-1
-
isoenzyme XT-I
-
0.0102 - 0.0145
perlecan-2
-
0.0094 - 0.0187
perlecan-3
-
0.0166
phosphacan
-
isoenzyme XT-I
-
0.01172 - 0.093
QEEEGSGGGQKK
0.26
rat L2 chondroitin sulfate
-
-
-
0.0023 - 0.0111
serglycin
-
0.545 - 0.677
silk fibroin
-
0.064 - 0.18
Smith-degraded chondroitin sulfate proteoglycan
-
0.0122 - 0.0178
syndecan
-
0.0074 - 0.0198
syndecan-1
-
0.0035 - 0.0141
syndecan-4
-
0.02 - 0.3905
TENEGSGLTNIK
0.0082 - 0.0103
testican-2
-
0.0029 - 0.0182
Thrombomodulin
-
0.0065 - 0.25
UDP-D-xylose
0.0065
UDP-xylose
-
cosubstrate: QEEEGSGGGQGG
0.0127 - 0.0146
versican-beta
-
0.155
[Smith-degraded chondroitin sulfate proteoglycan]-L-serine
-
-
-
0.0008
[Val36,Val38]delta1[Gly92,Ile94]delta2bikunin
-
-
additional information
additional information
-
0.0179
bamcan
-
isoenzyme XT-II
-
0.0222
bamcan
-
isoenzyme XT-I
-
0.0093
bFGF-peptide
-
isoenzyme XT-II
-
0.0137
bFGF-peptide
-
isoenzyme XT-I
-
0.0006
bikunin
-
recombinant mutant bikunin
-
0.0009
bikunin
-
recombinant wild-type bikunin
-
0.0009
bikunin
-
37Ā°C, pH 6.5
-
0.0009
bikunin
pH 6.5, 37Ā°C, wild-type enzyme
-
0.0009
bikunin
pH 6.5, 37Ā°C, mutant enzyme D316G
-
0.0009
bikunin
-
37Ā°C, pH 6.5, mutant enzyme DELTA1-184
-
0.001
bikunin
pH 6.5, 37Ā°C, wild-type enzyme
-
0.001
bikunin
pH 6.5, 37Ā°C, mutant enzyme C933A
-
0.0011
bikunin
pH 6.5, 37Ā°C, mutant enzyme D314G
-
0.0011
bikunin
pH 6.5, 37Ā°C, mutant enzyme D745E
-
0.0011
bikunin
-
37Ā°C, pH 6.5, mutant enzyme K262A
-
0.0011
bikunin
-
37Ā°C, pH 6.5, mutant enzyme R270A
-
0.0012
bikunin
pH 6.5, 37Ā°C, mutant enzyme C920A
-
0.0012
bikunin
pH 6.5, 37Ā°C, mutant enzyme W746D
-
0.0012
bikunin
pH 6.5, 37Ā°C, mutant enzyme W746G
-
0.0012
bikunin
-
37Ā°C, pH 6.5, mutant enzyme S269A
-
0.0013
bikunin
pH 6.5, 37Ā°C, mutant enzyme W746N
-
0.0013
bikunin
-
37Ā°C, pH 6.5, mutant enzyme E263A
-
0.0013
bikunin
-
37Ā°C, pH 6.5, mutant enzyme K272A
-
0.0013
bikunin
-
37Ā°C, pH 6.5, mutant enzyme S266A
-
0.0014
bikunin
pH 6.5, 37Ā°C, mutant enzyme C301A
-
0.0014
bikunin
pH 6.5, 37Ā°C, mutant enzyme C675A
-
0.0014
bikunin
-
37Ā°C, pH 6.5, mutant enzyme DELTA1-213
-
0.0014
bikunin
-
37Ā°C, pH 6.5, mutant enzyme DELTA1-260
-
0.0016
bikunin
pH 6.5, 37Ā°C, mutant enzyme C542A
-
0.002
bikunin
pH 6.5, 37Ā°C, mutant enzyme C927A
-
0.0028
bikunin
pH 6.5, 37Ā°C, mutant enzyme C285A
-
0.0044
bikunin
pH 6.5, 37Ā°C, mutant enzyme D747E
-
0.005
bikunin
-
37Ā°C, pH 6.5, mutant enzyme DELTA1-266
-
0.0053
bikunin
pH 6.5, 37Ā°C, mutant enzyme C257A
-
0.0054
bikunin
-
37Ā°C, pH 6.5, mutant enzyme DELTA1-272
-
0.0064
bikunin
-
isoenzyme XT-II with mutant bikunin (sequence QEE-GSGRGQLV)
-
0.0069
bikunin
pH 6.5, 37Ā°C, mutant enzyme D747G
-
0.0077
bikunin
-
isoenzyme XT-II with mutant bikunin (sequence QEEEGSGHNMLV)
-
0.0085
bikunin
-
isoenzyme XT-II with mutant bikunin (sequence QEEESSGGGQLV)
-
0.0093
bikunin
-
isoenzyme XT-II with mutant bikunin (sequence QEEEGSGSLALV)
-
0.0099
bikunin
-
isoenzyme XT-I with mutant bikunin (sequence QEEERSGGGQLV)
-
0.0103
bikunin
-
isoenzyme XT-I with mutant bikunin (sequence QEEESSGGGQLV)
-
0.0119
bikunin
pH 6.5, 37Ā°C, mutant enzyme C563A
-
0.0123
bikunin
-
isoenzyme XT-I with mutant bikunin (sequence QEE-GSGGGQLV)
-
0.0125
bikunin
-
isoenzyme XT-I with mutant bikunin (sequence QEEEGSGHNMLV)
-
0.0133
bikunin
-
isoenzyme XT-I with mutant bikunin (sequence QEEEGSSCGQLV)
-
0.0137
bikunin
-
isoenzyme XT-II with mutant bikunin (sequence QEEEGSGRRALV)
-
0.015
bikunin
-
isoenzyme XT-II with mutant bikunin (sequence QEEEGSGGRSVLV)
-
0.0151
bikunin
-
isoenzyme XT-I with mutant bikunin (sequence QEEEGSGCGQLV)
-
0.0153
bikunin
-
isoenzyme XT-I with mutant bikunin (sequence QEEEGSSGGQLV)
-
0.0199
bikunin
-
isoenzyme XT-I with mutant bikunin (sequence QEEEGSGSLALV)
-
0.02
bikunin
-
isoenzyme XT-I with mutant bikunin (sequence QKEEGSGGGQLV)
-
0.0205
bikunin
-
isoenzyme XT-I with mutant bikunin (sequence QEE-GSGRGQLV)
-
0.0215
bikunin
-
isoenzyme XT-II with mutant bikunin (sequence QEEEGSGCYKLV)
-
0.022
bikunin
recombinant enzyme
-
0.0227
bikunin
-
isoenzyme XT-II with mutant bikunin (sequence QEEEGSGCGQLV)
-
0.0242
bikunin
-
isoenzyme XT-II with mutant bikunin (sequence QEEEGSGRHLLV)
-
0.0243
bikunin
-
isoenzyme XT-I with mutant bikunin (sequence QEEESSGRGQLV)
-
0.0251
bikunin
-
isoenzyme XT-I with mutant bikunin (sequence QEEEGSGGRSVLV)
-
0.0274
bikunin
-
isoenzyme XT-I with wild-type bikunin (sequence QEEEGSGGGQLV)
-
0.0288
bikunin
-
isoenzyme XT-I with mutant bikunin (sequence QEEEGSTSLV)
-
0.0301
bikunin
-
isoenzyme XT-I with mutant bikunin (sequence QEEEGSGCYKLV)
-
0.0318
bikunin
-
isoenzyme XT-I with mutant bikunin (sequence QLTTGSGGGQLV)
-
0.0356
bikunin
-
isoenzyme XT-II with mutant bikunin (sequence QKEEGSGGGQLV)
-
0.0462
bikunin
-
isoenzyme XT-II with wild-type bikunin (sequence QEEEGSGGGQLV)
-
0.0463
bikunin
-
isoenzyme XT-II
-
0.0508
bikunin
-
isoenzyme XT-II with mutant bikunin (sequence QEEEGSGCRVLV)
-
0.0543
bikunin
-
isoenzyme XT-I with mutant bikunin (sequence QEEEGSGCRVLV)
-
0.0572
bikunin
-
isoenzyme XT-I with mutant bikunin (sequence QEEEGSGRHLLV)
-
0.0586
bikunin
-
isoenzyme XT-I with mutant bikunin (sequence QEEEGSGRRALV)
-
0.0656
bikunin
-
isoenzyme XT-I with mutant bikunin (sequence QPQIGSGGGQLV)
-
0.0025
biotin-NH-QEEEGSGGGQKK(5-fluorescein)-CONH2
-
XylT-I
0.0052
biotin-NH-QEEEGSGGGQKK(5-fluorescein)-CONH2
-
0.0061
biotin-NH-QEEEGSGGGQKK(5-fluorescein)-CONH2
-
XylT-II
0.11
cartilage chondroitin sulfate proteoglycan
-
-
-
0.155
cartilage chondroitin sulfate proteoglycan
-
trifluoromethanesulfonic acid-degraded substrate
-
0.19
cartilage chondroitin sulfate proteoglycan
-
hydrogen fluoride-degraded substrate
-
0.0208
fragment(1-24) of human basic fibroblast growth factor
-
native XT-I
-
0.0223
fragment(1-24) of human basic fibroblast growth factor
-
recombinant XT-I
-
0.0109
glypican-1
-
isoenzyme XT-II
-
0.0171
glypican-1
-
isoenzyme XT-I
-
0.00011
HF-degraded chondroitin sulfate proteoglycan
-
-
-
0.0029
HF-degraded chondroitin sulfate proteoglycan
-
-
-
1.02
HF-degraded chondroitin sulfate proteoglycan
-
-
-
0.0104
L-APLP2
-
isoenzyme XT-II
0.0134
L-APLP2
-
isoenzyme XT-I
0.0032
neuroglycan C
-
isoenzyme XT-II
-
0.0236
neuroglycan C
-
isoenzyme XT-I
-
0.0102
perlecan-2
-
isoenzyme XT-II
-
0.0145
perlecan-2
-
isoenzyme XT-I
-
0.0094
perlecan-3
-
isoenzyme XT-II
-
0.0187
perlecan-3
-
isoenzyme XT-I
-
0.01172
QEEEGSGGGQKK
-
in Xylt2
0.02048
QEEEGSGGGQKK
-
in Xylt1
20
Ser-Gly-Gly
-
-
0.0023
serglycin
-
isoenzyme XT-II
-
0.0111
serglycin
-
isoenzyme XT-I
-
0.545
silk fibroin
-
-
-
0.677
silk fibroin
recombinant enzyme
-
0.064
Smith-degraded chondroitin sulfate proteoglycan
-
-
-
0.18
Smith-degraded chondroitin sulfate proteoglycan
-
-
-
0.0122
syndecan
-
isoenzyme XT-II
-
0.0178
syndecan
-
isoenzyme XT-I
-
0.0074
syndecan-1
-
isoenzyme XT-II
-
0.0198
syndecan-1
-
isoenzyme XT-I
-
0.0035
syndecan-4
-
isoenzyme XT-I
-
0.0141
syndecan-4
-
isoenzyme XT-II
-
0.02
TENEGSGLTNIK
-
-
0.2132
TENEGSGLTNIK
-
in Xylt1
0.3905
TENEGSGLTNIK
-
in Xylt2
0.0082
testican-2
-
isoenzyme XT-II
-
0.0103
testican-2
-
isoenzyme XT-I
-
0.0029
Thrombomodulin
-
isoenzyme XT-II
-
0.0182
Thrombomodulin
-
isoenzyme XT-I
-
0.0065
UDP-D-xylose
-
-
0.01
UDP-D-xylose
-
cosubstrate: Smith-degraded chondroitin sulfate
0.019
UDP-D-xylose
-
Smith-degraded proteoglycan, value on serine basis
0.1
UDP-D-xylose
Drosophila sp. (in: flies)
-
cosubstrate: DDDSIEGSGGR
0.18
UDP-D-xylose
-
cosubstrate: CDEASGIGPDDRD
0.0127
versican-beta
-
isoenzyme XT-II
-
0.0146
versican-beta
-
isoenzyme XT-I
-
additional information
additional information
-
-
-
additional information
additional information
-
-
-
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42
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Homo sapiens
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Xylosyltransferase II is a significant contributor of circulating xylosyltransferase levels and platelets constitute an important source of xylosyltransferase in serum
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Identification and characterization of the human xylosyltransferase I gene promoter region
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284
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Homo sapiens
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Xylosyltransferase-I regulates glycosaminoglycan synthesis during the pathogenic process of human osteoarthritis
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7
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Rumi functions as both a protein O-glucosyltransferase and a protein O-xylosyltransferase
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Homo sapiens, Mus musculus
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Enzymatic analysis of the protein O-glycosyltransferase, Rumi, acting toward epidermal growth factor-like (EGF) repeats
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1022
119-128
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Drosophila melanogaster
brenda
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The protein O-glucosyltransferase Rumi modifies eyes shut to promote rhabdomere separation in Drosophila
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10
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2014
Drosophila melanogaster
brenda
de la Morena-Barrio, M.; Buil, A.; Anton, A.; Martinez-Martinez, I.; Minano, A.; Gutierrez-Gallego, R.; Navarro-Fernandez, J.; Aguila, S.; Souto, J.; Vicente, V.; Soria, J.; Corral, J.
Identification of antithrombin-modulating genes. Role of LARGE, a gene encoding a bifunctional glycosyltransferase, in the secretion of proteins?
PLoS ONE
8
e64998
2013
Homo sapiens
brenda