Literature summary for 2.7.4.14 extracted from

Pearman, A.T.; Castro-Faria-Neto, H.C.; McIntyre, T.M.; Prescott, S.M.; Stafforini, D.M.
Characterization of human UMP-CMP kinase enzymatic activity and 5' untranslated region (2001), Life Sci., 69, 2361-2370.

Metals/Ions

Metals/Ions	Comment	Organism	Structure
Mg2+	strong requirement, maximal activity at 3 mM	Homo sapiens

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
22222	-	x * 22222, calculation from nucleotide sequence	Homo sapiens

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
ATP + CMP	Homo sapiens	the enzyme is required during rapid cell growth	ADP + CDP	-	?

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue	Comment	Organism	Textmining
A-549 cell	lung carcinoma	Homo sapiens	-
bone marrow	-	Homo sapiens	-
Burkitt lymphoma cell	-	Homo sapiens	-
fetus	-	Homo sapiens	-
G-361 cell	melanoma cell	Homo sapiens	-
HeLa-S3 cell	-	Homo sapiens	-
K-562 cell	chronic myelogenous leukemia cell	Homo sapiens	-
leukocyte	-	Homo sapiens	-
liver	-	Homo sapiens	-
lymph node	-	Homo sapiens	-
macrophage	-	Homo sapiens	-
MOLT-4 cell	lymphoblastic leukemia cell	Homo sapiens	-
additional information	two mRNA species are expressed in all immune tissues examined, an all cases the 3.4 kb form is the more prominent RNA species	Homo sapiens	-
NCI-H660 cell	promyelocytic leukemia	Homo sapiens	-
peripheral blood mononuclear cell	-	Homo sapiens	-
RAJI cell	-	Homo sapiens	-
spleen	-	Homo sapiens	-
SW-480 cell	colorectal adenocarcinoma cell	Homo sapiens	-
thymus	-	Homo sapiens	-
vermiform appendix	-	Homo sapiens	-

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.
ATP + CMP	-	Homo sapiens	ADP + CDP	-	?
ATP + CMP	the enzyme is required during rapid cell growth	Homo sapiens	ADP + CDP	-	?
ATP + UMP	-	Homo sapiens	ADP + UDP	-	?

Subunits	Comment	Organism
?	x * 22222, calculation from nucleotide sequence	Homo sapiens