EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
6.1.1.2 | tryptophan-tRNA ligase |
cerebellum |
about 0.2% of total soluble protein |
306 |
6.3.2.11 | carnosine synthase |
cerebellum |
- |
993 |
5.1.99.4 | alpha-methylacyl-CoA racemase |
cerebellum |
weak |
2449 |
4.1.2.27 | sphinganine-1-phosphate aldolase |
cerebellum |
- |
5119 |
3.4.17.22 | metallocarboxypeptidase D |
cerebellum |
- |
28967 |
3.1.2.1 | acetyl-CoA hydrolase |
cerebellum |
- |
94468 |
3.4.14.2 | dipeptidyl-peptidase II |
cerebellum |
- |
651779, 95240 |
3.1.3.9 | glucose-6-phosphatase |
cerebellum |
- |
134945 |
3.1.4.37 | 2',3'-cyclic-nucleotide 3'-phosphodiesterase |
cerebellum |
- |
135424 |
3.4.13.18 | cytosol nonspecific dipeptidase |
cerebellum |
- |
137183 |
3.1.4.39 | alkylglycerophosphoethanolamine phosphodiesterase |
cerebellum |
- |
208395 |
3.5.4.4 | adenosine deaminase |
cerebellum |
- |
209610, 711639 |
3.6.1.13 | ADP-ribose diphosphatase |
cerebellum |
- |
209946, 655991 |
3.5.1.3 | omega-amidase |
cerebellum |
- |
288894 |
1.2.3.1 | aldehyde oxidase |
cerebellum |
- |
390422 |
1.8.5.1 | glutathione dehydrogenase (ascorbate) |
cerebellum |
myelin sheet |
394026 |
1.8.5.1 | glutathione dehydrogenase (ascorbate) |
cerebellum |
within the myelin sheets |
394026 |
1.8.5.1 | glutathione dehydrogenase (ascorbate) |
cerebellum |
- |
394027 |
1.14.19.3 | acyl-CoA 6-desaturase |
cerebellum |
neurons |
438421 |
1.13.11.34 | arachidonate 5-lipoxygenase |
cerebellum |
high level of expression |
439477 |
2.3.1.50 | serine C-palmitoyltransferase |
cerebellum |
granule cells, neuronal cells |
487169 |
2.3.1.50 | serine C-palmitoyltransferase |
cerebellum |
Purkinje cells |
487177 |
2.3.2.2 | gamma-glutamyltransferase |
cerebellum |
- |
487930 |
2.4.1.47 | N-acylsphingosine galactosyltransferase |
cerebellum |
cerebrum, cerebellum and brain stem of 14 and 21 days old rats |
489223 |
2.7.10.2 | non-specific protein-tyrosine kinase |
cerebellum |
- |
490542 |
2.7.11.15 | beta-adrenergic-receptor kinase |
cerebellum |
brain: highest beta-ARK mRNA concentrations in cerebral cortex and cerebellum |
490985 |
2.7.11.15 | beta-adrenergic-receptor kinase |
cerebellum |
- |
491003 |
2.4.1.206 | lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase |
cerebellum |
neonatal |
638232 |
2.4.1.206 | lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase |
cerebellum |
- |
-, 638234, 638235, 721936 |
2.4.1.206 | lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase |
cerebellum |
distinct cellular layers: Purkinje cell layer, molecular cell layer, granule cell layer + white matter |
638234, 638236 |
2.4.1.275 | neolactotriaosylceramide beta-1,4-galactosyltransferase |
cerebellum |
specific activities of Gal-Tr in the granule cell layer and white matter is approximately 66% of that in the molecular layer. Gal-Tr in the homogenate of cerebellum declines by approximately 35-45% from postnatal day 3 to 14. Gal-Tr activity in the granule cells does not change with age. The relative Gal-Tr activity in granule cells to homogenate is between 0.13 and 0.23 |
638234 |
2.4.1.150 | N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase |
cerebellum |
IGnT is highly expressed in adult cerebellum |
638567 |
2.4.1.149 | N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase |
cerebellum |
very weak expression of beta3GnT7 |
-, 638581 |
2.4.1.86 | N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase |
cerebellum |
specific activity is reduced by 50% soon after birth and then remains practically the same with development |
639633 |
2.4.3.8 | alpha-N-acetylneuraminate alpha-2,8-sialyltransferase |
cerebellum |
- |
639661, 760219 |
2.7.1.107 | diacylglycerol kinase (ATP) |
cerebellum |
- |
640386, 705262 |
2.7.4.21 | inositol-hexakisphosphate 5-kinase |
cerebellum |
- |
642554, 738903 |
2.7.4.21 | inositol-hexakisphosphate 5-kinase |
cerebellum |
highest activity occurs in Purkinje cells with somewhat lower levels in granule cells. In hippocampus substantial densities occur in CA1-CA4 layers of the hippocampus as well as the dentate gyrus |
642554 |
3.4.24.81 | ADAM10 endopeptidase |
cerebellum |
the expression is increased 2-fold in Alzheimer disease |
644076 |
1.17.1.4 | xanthine dehydrogenase |
cerebellum |
- |
644557, 644558 |
1.17.1.4 | xanthine dehydrogenase |
cerebellum |
high rate of dehydrogenase activity |
644557, 644558 |
1.21.99.3 | thyroxine 5-deiodinase |
cerebellum |
isozyme type III |
-, 644807 |
1.21.99.3 | thyroxine 5-deiodinase |
cerebellum |
Purkinje cells |
-, 644807 |
2.8.1.2 | 3-mercaptopyruvate sulfurtransferase |
cerebellum |
- |
645561, 645562, 739651 |
2.8.2.20 | protein-tyrosine sulfotransferase |
cerebellum |
- |
645805, 645807 |
3.1.2.2 | palmitoyl-CoA hydrolase |
cerebellum |
- |
646167 |
3.1.2.20 | acyl-CoA hydrolase |
cerebellum |
- |
646167 |
3.4.14.10 | tripeptidyl-peptidase II |
cerebellum |
- |
647155, 664475 |
3.4.14.9 | tripeptidyl-peptidase I |
cerebellum |
activity in neuroglia cells, no activity in small granule cells, Purkinje cells, remified dendrites and myelinated fibers |
647183 |
3.4.19.6 | pyroglutamyl-peptidase II |
cerebellum |
- |
647288 |
3.4.21.B12 | prostase |
cerebellum |
low expression level |
647334 |
3.4.21.117 | stratum corneum chymotryptic enzyme |
cerebellum |
- |
647349 |
3.4.21.B40 | kallikrein 9 |
cerebellum |
- |
647358 |
3.4.22.56 | caspase-3 |
cerebellum |
- |
647612 |
3.1.4.35 | 3',5'-cyclic-GMP phosphodiesterase |
cerebellum |
- |
650180, 650342, 716347 |
3.4.11.2 | membrane alanyl aminopeptidase |
cerebellum |
- |
651265 |
3.4.21.B25 | PACE4 proprotein convertase |
cerebellum |
- |
651744 |
3.4.22.1 | cathepsin B |
cerebellum |
cerebellar cultures |
652160 |
3.1.4.35 | 3',5'-cyclic-GMP phosphodiesterase |
cerebellum |
strongest PDE9A expression in Purkinje cells |
652975 |
6.3.2.2 | glutamate-cysteine ligase |
cerebellum |
- |
652979, 672367 |
3.1.4.37 | 2',3'-cyclic-nucleotide 3'-phosphodiesterase |
cerebellum |
cerebellar postsynaptic density fraction, both isoforms CNP1 and CNP2 are expressed in cerian populations of cerebellar cells, in oligodendrocytes, Purkinje cells and unidentified PSD95-positive cells, not in granule cells |
653229 |
3.1.2.22 | palmitoyl[protein] hydrolase |
cerebellum |
- |
653243 |
3.1.1.7 | acetylcholinesterase |
cerebellum |
- |
653349, 679180, 680122, 682110 |
3.1.1.4 | phospholipase A2 |
cerebellum |
- |
653367 |
3.4.21.112 | site-1 protease |
cerebellum |
- |
653621 |
1.1.1.146 | 11beta-hydroxysteroid dehydrogenase |
cerebellum |
- |
654196 |
1.1.1.B40 | 11beta-hydroxysteroid dehydrogenase (NAD+) |
cerebellum |
- |
654196 |
3.1.3.16 | protein-serine/threonine phosphatase |
cerebellum |
- |
655140 |
3.6.1.28 | thiamine-triphosphatase |
cerebellum |
- |
655198, 668963 |
1.4.3.5 | pyridoxal 5'-phosphate synthase |
cerebellum |
13.3% of the activity in liver detected in left cerebellum, 25.0% of the activity in liver detected in the right cerebellum |
655483 |
1.8.4.12 | peptide-methionine (R)-S-oxide reductase |
cerebellum |
- |
657722, 711940 |
2.4.1.41 | polypeptide N-acetylgalactosaminyltransferase |
cerebellum |
- |
658240 |
2.3.1.42 | glycerone-phosphate O-acyltransferase |
cerebellum |
- |
658362 |
1.13.11.27 | 4-hydroxyphenylpyruvate dioxygenase |
cerebellum |
abundantly expressed in neurons of |
658410 |
1.6.1.2 | NAD(P)+ transhydrogenase (Re/Si-specific) |
cerebellum |
- |
658473 |
2.4.1.41 | polypeptide N-acetylgalactosaminyltransferase |
cerebellum |
enzyme form pp-GalNAc-T15 |
658739 |
1.8.3.2 | thiol oxidase |
cerebellum |
- |
659578 |
1.6.5.2 | NAD(P)H dehydrogenase (quinone) |
cerebellum |
the ratio of frontal to cerebellar NQO1 activity is significantly increased in patients with Alzheimers disease versus controls |
660005 |
2.3.1.6 | choline O-acetyltransferase |
cerebellum |
33% of activity membrane associated |
660007 |
2.6.1.1 | aspartate transaminase |
cerebellum |
- |
660009 |
5.1.1.18 | serine racemase |
cerebellum |
increase of enzyme expression after birth |
660638 |
5.6.2.2 | DNA topoisomerase (ATP-hydrolysing) |
cerebellum |
- |
660815 |
2.7.7.1 | nicotinamide-nucleotide adenylyltransferase |
cerebellum |
- |
660960 |
2.7.1.68 | 1-phosphatidylinositol-4-phosphate 5-kinase |
cerebellum |
granule cells |
660965 |
6.2.1.16 | acetoacetate-CoA ligase |
cerebellum |
expression of AACS mRNA in the cerebellum is restricted primarily to glial cells |
661256 |
2.7.11.13 | protein kinase C |
cerebellum |
ontogenetic isozyme profiling |
661408 |
2.7.1.91 | sphingosine kinase |
cerebellum |
- |
661509, 675516 |
2.7.11.12 | cGMP-dependent protein kinase |
cerebellum |
Purkinje cells |
661575 |
2.7.1.20 | adenosine kinase |
cerebellum |
- |
661642 |
2.7.11.13 | protein kinase C |
cerebellum |
granule cells |
661662 |
2.7.1.60 | N-acylmannosamine kinase |
cerebellum |
- |
661666 |
2.4.1.214 | glycoprotein 3-alpha-L-fucosyltransferase |
cerebellum |
- |
661837 |
2.7.11.22 | cyclin-dependent kinase |
cerebellum |
- |
662124, 664179 |
2.7.11.26 | tau-protein kinase |
cerebellum |
- |
662124, 679431, 681536, 705911, 760847 |
2.6.1.42 | branched-chain-amino-acid transaminase |
cerebellum |
neurons of adult animal |
662522 |
5.6.2.1 | DNA topoisomerase |
cerebellum |
- |
662523 |
2.7.1.1 | hexokinase |
cerebellum |
type III isozyme |
662531 |
2.7.1.138 | ceramide kinase |
cerebellum |
- |
662592 |
2.7.1.138 | ceramide kinase |
cerebellum |
high activity |
662592 |
2.7.11.1 | non-specific serine/threonine protein kinase |
cerebellum |
expression of CK1epsilon-2, CK1epsilon-1 |
662955 |