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Information on EC 2.6.1.1 - aspartate transaminase

for references in articles please use BRENDA:EC2.6.1.1

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IUBMB Comments

A pyridoxal-phosphate protein. Also acts on L-tyrosine, L-phenylalanine and L-tryptophan. Aspartate transaminase activity can be formed from the aromatic-amino-acid transaminase (EC 2.6.1.57) of Escherichia coli by controlled proteolysis , some EC 2.6.1.57 activity can be found in this enzyme from other sources ; indeed the enzymes are identical in Trichomonas vaginalis .

The expected taxonomic range for this enzyme is: Eukaryota, Bacteria, Archaea

Synonyms
aspartate transaminase, asat, glutamic oxaloacetic transaminase, glutamate oxaloacetate transaminase, glutamic-oxaloacetic transaminase, asp at, aspat, aspartate at, glutamic-oxalacetic transaminase, aat-2, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate
show the reaction diagram
PATHWAY SOURCE
PATHWAYS
MetaCyc
(R)-cysteate degradation, (S)-reticuline biosynthesis I, 3-(4-hydroxyphenyl)pyruvate biosynthesis, 4-hydroxybenzoate biosynthesis I (eukaryotes), anaerobic energy metabolism (invertebrates, cytosol), atromentin biosynthesis, C4 photosynthetic carbon assimilation cycle, NAD-ME type, C4 photosynthetic carbon assimilation cycle, PEPCK type, coenzyme M biosynthesis II, indole-3-acetate biosynthesis II, indole-3-acetate biosynthesis VI (bacteria), L-asparagine degradation III (mammalian), L-aspartate biosynthesis, L-aspartate degradation I, L-glutamate degradation II, L-phenylalanine biosynthesis I, L-phenylalanine degradation II (anaerobic), L-phenylalanine degradation III, L-phenylalanine degradation IV (mammalian, via side chain), L-phenylalanine degradation VI (reductive Stickland reaction), L-tryptophan degradation IV (via indole-3-lactate), L-tryptophan degradation VIII (to tryptophol), L-tryptophan degradation XIII (reductive Stickland reaction), L-tyrosine biosynthesis I, L-tyrosine degradation I, L-tyrosine degradation II, L-tyrosine degradation III, L-tyrosine degradation IV (to 4-methylphenol), L-tyrosine degradation V (reductive Stickland reaction), malate/L-aspartate shuttle pathway, rosmarinic acid biosynthesis I, sulfolactate degradation III, TCA cycle VIII (Chlamydia)
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