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Literature summary for 3.1.2.2 extracted from

  • Yamada, J.; Furihata, T.; Tamura, H.; Watanabe, T.; Suga, T.
    Long-chain acyl-CoA hydrolase from rat brain cytosol: purification, characterization, and immunohistochemical localization (1996), Arch. Biochem. Biophys., 326, 106-114.
    View publication on PubMed
Search for more literature for 3.1.2.2

General Stability

General Stability Organism
20% ethylene glycol or 0.001mM ammonium sulfate overcomes cold lability Rattus norvegicus

Inhibitors

Inhibitors Comment Organism Structure
Ca2+
-
 Bos taurus
Ca2+
-
 Oryctolagus cuniculus
Ca2+
-
 Rattus norvegicus
Mg2+
-
 Bos taurus
Mg2+
-
 Rattus norvegicus
Mn2+
-
 Bos taurus
Mn2+
-
 Rattus norvegicus
Mn2+
-
 Sus scrofa
p-chloromercuribenzoic acid
-
 Rattus norvegicus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0057
-
 hexadecanoyl-CoA
-
 Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Homo sapiens 5829
-
cytosol
-
 Rattus norvegicus 5829
-
cytosol
-
 Sus scrofa 5829
-
cytosol
-
 Oryctolagus cuniculus 5829
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
36000
-
 3 * 36000, SDs-PAGE Rattus norvegicus
104000
-
 gel filtration Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
palmitoyl-CoA + H2O Cavia porcellus
-
 CoA + palmitate
-
 ?
palmitoyl-CoA + H2O Homo sapiens
-
 CoA + palmitate
-
 ?
palmitoyl-CoA + H2O Rattus norvegicus
-
 CoA + palmitate
-
 ?
palmitoyl-CoA + H2O Sus scrofa
-
 CoA + palmitate
-
 ?
palmitoyl-CoA + H2O Oryctolagus cuniculus
-
 CoA + palmitate
-
 ?
palmitoyl-CoA + H2O Canis lupus familiaris
-
 CoA + palmitate
-
 ?
palmitoyl-CoA + H2O Mesocricetus auratus
-
 CoA + palmitate
-
 ?
palmitoyl-CoA + H2O Platyrrhini
-
 CoA + palmitate
-
 ?

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-
Canis lupus familiaris
-
 beagle
-
Cavia porcellus
-
 albino Hartley guinea pig
-
Homo sapiens
-
-
-
Mesocricetus auratus
-
-
-
Oryctolagus cuniculus
-
 Japanese white rabbit
-
Platyrrhini
-
 crab eating
-
Rattus norvegicus
-
 Wistar rats
-
Sus scrofa
-
-
-

Purification (Commentary)

Purification (Comment) Organism
680fold Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Cavia porcellus
-
brain
-
 Homo sapiens
-
brain
-
 Rattus norvegicus
-
brain
-
 Sus scrofa
-
brain
-
 Bos taurus
-
brain
-
 Oryctolagus cuniculus
-
brain
-
 Canis lupus familiaris
-
brain
-
 Mesocricetus auratus
-
brain
-
 Platyrrhini
-
cerebellum
-
 Rattus norvegicus
-
cerebral cortex
-
 Cavia porcellus
-
cerebral cortex
-
 Rattus norvegicus
-
corpus striatum
-
 Rattus norvegicus
-
hippocampus
-
 Rattus norvegicus
-
medulla oblongata
-
 Rattus norvegicus
-
additional information
-
 Rattus norvegicus
-
neuron
-
 Rattus norvegicus
-
olfactory bulb
-
 Rattus norvegicus
-
pons
-
 Rattus norvegicus
-
spinal cord
-
 Rattus norvegicus
-

Storage Stability

Storage Stability Organism
stable at 25°C over 24 h Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
hexadecanoyl-CoA + H2O i.e. palmitoyl-CoA Cavia porcellus CoA + hexadecanoate
-
 ?
hexadecanoyl-CoA + H2O i.e. palmitoyl-CoA Homo sapiens CoA + hexadecanoate
-
 ?
hexadecanoyl-CoA + H2O i.e. palmitoyl-CoA Rattus norvegicus CoA + hexadecanoate
-
 ?
hexadecanoyl-CoA + H2O i.e. palmitoyl-CoA Sus scrofa CoA + hexadecanoate
-
 ?
hexadecanoyl-CoA + H2O i.e. palmitoyl-CoA Oryctolagus cuniculus CoA + hexadecanoate
-
 ?
hexadecanoyl-CoA + H2O i.e. palmitoyl-CoA Mesocricetus auratus CoA + hexadecanoate
-
 ?
hexadecanoyl-CoA + H2O i.e. palmitoyl-CoA Platyrrhini CoA + hexadecanoate
-
 ?
octadecanoyl-CoA + H2O i.e. stearoyl-CoA Rattus norvegicus CoA + octadecanoate
-
 ?
oleoyl-CoA + H2O
-
 Cavia porcellus CoA + oleate
-
 ?
oleoyl-CoA + H2O
-
 Homo sapiens CoA + oleate
-
 ?
oleoyl-CoA + H2O
-
 Rattus norvegicus CoA + oleate
-
 ?
oleoyl-CoA + H2O
-
 Sus scrofa CoA + oleate
-
 ?
oleoyl-CoA + H2O
-
 Bos taurus CoA + oleate
-
 ?
oleoyl-CoA + H2O
-
 Oryctolagus cuniculus CoA + oleate
-
 ?
palmitoyl-CoA + H2O
-
 Cavia porcellus CoA + palmitate
-
 ?
palmitoyl-CoA + H2O
-
 Homo sapiens CoA + palmitate
-
 ?
palmitoyl-CoA + H2O
-
 Rattus norvegicus CoA + palmitate
-
 ?
palmitoyl-CoA + H2O
-
 Sus scrofa CoA + palmitate
-
 ?
palmitoyl-CoA + H2O
-
 Oryctolagus cuniculus CoA + palmitate
-
 ?
palmitoyl-CoA + H2O
-
 Canis lupus familiaris CoA + palmitate
-
 ?
palmitoyl-CoA + H2O
-
 Mesocricetus auratus CoA + palmitate
-
 ?
palmitoyl-CoA + H2O
-
 Platyrrhini CoA + palmitate
-
 ?

Subunits

Subunits Comment Organism
trimer 3 * 36000, SDs-PAGE Rattus norvegicus

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
30
-
-
 Rattus norvegicus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.1 8.3
-
 Rattus norvegicus