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Literature summary for 1.8.3.2 extracted from
- FAD-linked sulfhydryl oxidase QSOX: topographic, cellular, and subcellular immunolocalization in adult rat central nervous system (2004), J. Comp. Neurol., 473, 334-363.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| Golgi apparatus | - |
Rattus norvegicus | 5794 | - |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 70000 | - |
x * 70000, SDS-PAGE | Rattus norvegicus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| R-SH + O2 | Rattus norvegicus | enzyme plays a role in secreted peptide/protein folding in the brain | R-S-S-R + H2O2 | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
Sprague-Dawley rats | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| basal telencephalon | - |
Rattus norvegicus | - |
| brain | - |
Rattus norvegicus | - |
| brain stem | - |
Rattus norvegicus | - |
| central nervous system | - |
Rattus norvegicus | - |
| cerebellum | - |
Rattus norvegicus | - |
| hippocampus | - |
Rattus norvegicus | - |
| hypothalamic nucleus | - |
Rattus norvegicus | - |
| hypothalamus | high expression in neurons producing disulfide-bounded neuropeptides | Rattus norvegicus | - |
| isocortex | - |
Rattus norvegicus | - |
| additional information | detailed analysis of cellular and subcellular enzyme localization, overview | Rattus norvegicus | - |
| neuron | especially in neurons throughout the rostrocaudal extent of the brain as well as in the spinal cord, in olfactory bulbs, isocortex, hippocampus, basal telencephalon, several thalamic and hypothalamic nuclei, cerebellum, and brainstem nuclei | Rattus norvegicus | - |
| olfactory bulb | - |
Rattus norvegicus | - |
| seminal vesicle | - |
Rattus norvegicus | - |
| spinal cord | - |
Rattus norvegicus | - |
| thalamic nucleus | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| R-SH + O2 | - |
Rattus norvegicus | R-S-S-R + H2O2 | - |
? | |
| R-SH + O2 | enzyme plays a role in secreted peptide/protein folding in the brain | Rattus norvegicus | R-S-S-R + H2O2 | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 70000, SDS-PAGE | Rattus norvegicus |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| More | enzyme belongs to the sulfhydryl oxidase/Quiescin Q6 family | Rattus norvegicus |
| QSOX | - |
Rattus norvegicus |
| sulfhydryl oxidase | - |
Rattus norvegicus |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| FAD | - |
Rattus norvegicus | |
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Release 2023.1 (January 2023)
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