EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
2.3.1.23 | 1-acylglycerophosphocholine O-acyltransferase |
cerebellum |
- |
755989 |
2.7.1.68 | 1-phosphatidylinositol-4-phosphate 5-kinase |
cerebellum |
granule cells |
660965 |
1.5.1.21 | 1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase (NADPH) |
cerebellum |
- |
741580 |
1.1.1.315 | 11-cis-retinol dehydrogenase |
cerebellum |
6% mRNA expression of Rdh5 compared to liver |
690797 |
1.1.1.146 | 11beta-hydroxysteroid dehydrogenase |
cerebellum |
- |
654196 |
1.1.1.B40 | 11beta-hydroxysteroid dehydrogenase (NAD+) |
cerebellum |
- |
654196 |
1.1.1.62 | 17beta-estradiol 17-dehydrogenase |
cerebellum |
- |
688956 |
1.1.1.62 | 17beta-estradiol 17-dehydrogenase |
cerebellum |
high expression |
685803 |
3.1.4.37 | 2',3'-cyclic-nucleotide 3'-phosphodiesterase |
cerebellum |
- |
135424 |
3.1.4.37 | 2',3'-cyclic-nucleotide 3'-phosphodiesterase |
cerebellum |
cerebellar postsynaptic density fraction, both isoforms CNP1 and CNP2 are expressed in cerian populations of cerebellar cells, in oligodendrocytes, Purkinje cells and unidentified PSD95-positive cells, not in granule cells |
653229 |
1.2.1.105 | 2-oxoglutarate dehydrogenase system |
cerebellum |
- |
673870, 675552, 676088, 762740 |
3.1.4.53 | 3',5'-cyclic-AMP phosphodiesterase |
cerebellum |
- |
678086, 716347 |
3.1.4.53 | 3',5'-cyclic-AMP phosphodiesterase |
cerebellum |
PDE4D11 expression levels increase in the cerebellum with progressive age |
691716 |
3.1.4.35 | 3',5'-cyclic-GMP phosphodiesterase |
cerebellum |
- |
650180, 650342, 716347 |
3.1.4.35 | 3',5'-cyclic-GMP phosphodiesterase |
cerebellum |
strongest PDE9A expression in Purkinje cells |
652975 |
3.1.4.17 | 3',5'-cyclic-nucleotide phosphodiesterase |
cerebellum |
- |
670448, 716347, 751697 |
1.1.1.31 | 3-hydroxyisobutyrate dehydrogenase |
cerebellum |
- |
722472 |
2.8.1.2 | 3-mercaptopyruvate sulfurtransferase |
cerebellum |
- |
645561, 645562, 739651 |
1.2.4.4 | 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) |
cerebellum |
- |
725082 |
1.1.1.145 | 3beta-hydroxy-DELTA5-steroid dehydrogenase |
cerebellum |
- |
740503 |
2.6.1.19 | 4-aminobutyrate-2-oxoglutarate transaminase |
cerebellum |
- |
676156 |
1.13.11.27 | 4-hydroxyphenylpyruvate dioxygenase |
cerebellum |
abundantly expressed in neurons of |
658410 |
1.14.13.29 | 4-nitrophenol 2-monooxygenase |
cerebellum |
- |
673929 |
3.1.3.5 | 5'-nucleotidase |
cerebellum |
- |
677509 |
6.2.1.16 | acetoacetate-CoA ligase |
cerebellum |
expression of AACS mRNA in the cerebellum is restricted primarily to glial cells |
661256 |
6.2.1.16 | acetoacetate-CoA ligase |
cerebellum |
low expression level |
691065 |
6.4.1.2 | acetyl-CoA carboxylase |
cerebellum |
ACC is inhibited in Cu-deficient cerebella |
691556 |
3.1.2.1 | acetyl-CoA hydrolase |
cerebellum |
- |
94468 |
3.1.1.7 | acetylcholinesterase |
cerebellum |
- |
653349, 679180, 680122, 682110 |
1.14.19.3 | acyl-CoA 6-desaturase |
cerebellum |
neurons |
438421 |
3.1.2.20 | acyl-CoA hydrolase |
cerebellum |
- |
646167 |
1.3.3.6 | acyl-CoA oxidase |
cerebellum |
- |
712822 |
3.1.1.23 | acylglycerol lipase |
cerebellum |
- |
-, 650849, 653676, 664468, 664469, 664576, 681285, 693824, 708263, 714639, 750615 |
3.4.24.81 | ADAM10 endopeptidase |
cerebellum |
the expression is increased 2-fold in Alzheimer disease |
644076 |
3.4.24.82 | ADAMTS-4 endopeptidase |
cerebellum |
- |
667468 |
3.5.4.4 | adenosine deaminase |
cerebellum |
- |
209610, 711639 |
2.7.1.20 | adenosine kinase |
cerebellum |
- |
661642 |
3.6.1.71 | adenosine-5'-diphospho-5'-[DNA] diphosphatase |
cerebellum |
- |
755241 |
4.6.1.1 | adenylate cyclase |
cerebellum |
- |
682285, 691561, 693757 |
4.6.1.1 | adenylate cyclase |
cerebellum |
highest AC1 expression, present in molecular layer, weak AC8 expression at postnatal day 7 and decreases further by postnatal day 14 |
-, 682136 |
3.6.1.13 | ADP-ribose diphosphatase |
cerebellum |
- |
209946, 655991 |
1.2.3.1 | aldehyde oxidase |
cerebellum |
- |
390422 |
1.14.16.5 | alkylglycerol monooxygenase |
cerebellum |
- |
688220 |
3.1.4.39 | alkylglycerophosphoethanolamine phosphodiesterase |
cerebellum |
- |
208395 |
3.2.1.28 | alpha,alpha-trehalase |
cerebellum |
- |
750882 |
5.1.99.4 | alpha-methylacyl-CoA racemase |
cerebellum |
weak |
2449 |
2.4.3.8 | alpha-N-acetylneuraminate alpha-2,8-sialyltransferase |
cerebellum |
- |
639661, 760219 |
2.3.1.108 | alpha-tubulin N-acetyltransferase |
cerebellum |
- |
736795 |
3.5.1.4 | amidase |
cerebellum |
- |
-, 664468, 664469, 681315 |
3.4.11.6 | aminopeptidase B |
cerebellum |
- |
665836, 682114 |
3.5.4.6 | AMP deaminase |
cerebellum |
- |
711639 |
3.4.17.23 | angiotensin-converting enzyme 2 |
cerebellum |
low ACE mRNA expression |
668892 |
1.13.11.34 | arachidonate 5-lipoxygenase |
cerebellum |
- |
684399 |
1.13.11.34 | arachidonate 5-lipoxygenase |
cerebellum |
high level of expression |
439477 |
1.13.11.34 | arachidonate 5-lipoxygenase |
cerebellum |
highest expresion of the enzyme in brain |
-, 689167 |
4.1.1.19 | arginine decarboxylase |
cerebellum |
- |
692560 |
4.3.2.1 | argininosuccinate lyase |
cerebellum |
- |
708319 |
4.1.1.28 | aromatic-L-amino-acid decarboxylase |
cerebellum |
- |
702968 |
2.8.2.1 | aryl sulfotransferase |
cerebellum |
SULT1A1 |
672845 |
2.6.1.1 | aspartate transaminase |
cerebellum |
- |
660009 |
2.7.11.15 | beta-adrenergic-receptor kinase |
cerebellum |
- |
491003 |
2.7.11.15 | beta-adrenergic-receptor kinase |
cerebellum |
brain: highest beta-ARK mRNA concentrations in cerebral cortex and cerebellum |
490985 |
6.3.2.62 | beta-tubulin-glutamate ligase |
cerebellum |
- |
751019 |
1.3.1.24 | biliverdin reductase |
cerebellum |
- |
711794, 724423, 725769 |
3.5.1.12 | biotinidase |
cerebellum |
- |
669619 |
1.2.1.25 | branched-chain alpha-keto acid dehydrogenase system |
cerebellum |
within the cerebellum, there is punctate labelling in the processes of cells within the Purkinje cell layer, most likely to be Bergmann astrocytes. The Purkinje cells themselves are unlabelled (12/18 brains examined) or weakly immunopositive. Within the granule cell layer, rosette like structures (glomeruli) are immunopositive. Within the deep cerebellar nuclei, there is strong granular immunopositivity in small glial cells in contrast to the largely immunonegative neurons |
763513 |
2.6.1.42 | branched-chain-amino-acid transaminase |
cerebellum |
- |
673846, 675509 |
2.6.1.42 | branched-chain-amino-acid transaminase |
cerebellum |
neurons of adult animal |
662522 |
2.7.11.17 | Ca2+/calmodulin-dependent protein kinase |
cerebellum |
- |
693764, 693768 |
2.7.11.17 | Ca2+/calmodulin-dependent protein kinase |
cerebellum |
alpha and beta isozymes, cerebellar nuclei |
664278 |
2.7.11.17 | Ca2+/calmodulin-dependent protein kinase |
cerebellum |
cerebellar granule cells |
-, 741420 |
3.4.22.B25 | calpain 5 |
cerebellum |
strong expression |
663847 |
3.4.22.52 | calpain-1 |
cerebellum |
- |
709152 |
2.7.11.11 | cAMP-dependent protein kinase |
cerebellum |
- |
-, 762271 |
4.2.1.1 | carbonic anhydrase |
cerebellum |
carbonic anhydrase XIII |
679413 |
3.4.17.1 | carboxypeptidase A |
cerebellum |
- |
-, 686638 |
6.3.2.11 | carnosine synthase |
cerebellum |
- |
993 |
3.4.22.56 | caspase-3 |
cerebellum |
- |
647612 |
2.1.1.6 | catechol O-methyltransferase |
cerebellum |
- |
685455 |
3.4.22.1 | cathepsin B |
cerebellum |
- |
700456 |
3.4.22.1 | cathepsin B |
cerebellum |
cerebellar cultures |
652160 |
3.4.23.5 | cathepsin D |
cerebellum |
- |
712050 |
3.4.22.41 | cathepsin F |
cerebellum |
- |
670246 |
3.4.22.27 | cathepsin S |
cerebellum |
- |
697041 |
3.4.18.1 | cathepsin X |
cerebellum |
- |
683448 |
3.5.1.23 | ceramidase |
cerebellum |
alkaline ceramidase |
719197 |
2.7.1.138 | ceramide kinase |
cerebellum |
- |
662592 |
2.7.1.138 | ceramide kinase |
cerebellum |
high activity |
662592 |
2.7.11.12 | cGMP-dependent protein kinase |
cerebellum |
- |
-, 704490, 721741 |
2.7.11.12 | cGMP-dependent protein kinase |
cerebellum |
predominant expression of isozyme cGKIalpha |
662962 |
2.7.11.12 | cGMP-dependent protein kinase |
cerebellum |
Purkinje cells |
661575 |
1.14.14.25 | cholesterol 24-hydroxylase |
cerebellum |
cerebellar interneurons and Purkinje cells |
687987 |
2.3.1.6 | choline O-acetyltransferase |
cerebellum |
- |
756641 |
2.3.1.6 | choline O-acetyltransferase |
cerebellum |
33% of activity membrane associated |
660007 |
2.7.7.15 | choline-phosphate cytidylyltransferase |
cerebellum |
- |
761598 |
2.8.2.5 | chondroitin 4-sulfotransferase |
cerebellum |
- |
674592 |
5.1.3.19 | chondroitin-glucuronate 5-epimerase |
cerebellum |
- |
715134 |
2.3.3.1 | citrate (Si)-synthase |
cerebellum |
- |
720554 |
2.7.3.2 | creatine kinase |
cerebellum |
- |
-, 675783, 705502, 739050 |
2.7.3.2 | creatine kinase |
cerebellum |
creatine kinase activity is not altered if rats are submitted to renal ischemia |
-, 689220 |