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Information on EC 2.3.1.23 - 1-acylglycerophosphocholine O-acyltransferase

for references in articles please use BRENDA:EC2.3.1.23

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IUBMB Comments

Acts preferentially with unsaturated acyl-CoA derivatives. 1-Acyl-sn-glycero-3-phosphoinositol can also act as acceptor.

The enzyme appears in viruses and cellular organisms

Synonyms
pcat1, lpcat3, lpcat, lysophosphatidylcholine acyltransferase, alcat1, lpcat2, lysolecithin acyltransferase, lycat, lyso-paf acetyltransferase, lysophosphatidylcholine acyltransferase 1, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
acyl-CoA + 1-acyl-sn-glycero-3-phosphocholine = CoA + 1,2-diacyl-sn-glycero-3-phosphocholine
show the reaction diagram
PATHWAY SOURCE
PATHWAYS
MetaCyc
arachidonate biosynthesis I (6-desaturase, lower eukaryotes), dimorphecolate biosynthesis, docosahexaenoate biosynthesis I (lower eukaryotes), hydroxylated fatty acid biosynthesis (plants), icosapentaenoate biosynthesis I (lower eukaryotes), linoleate biosynthesis I (plants), phosphatidylcholine acyl editing, phosphatidylcholine biosynthesis VII, phospholipid remodeling (phosphatidylcholine, yeast), phospholipid remodeling (phosphatidylethanolamine, yeast), ricinoleate biosynthesis
Highest Expressing Human Cell Lines
Cell Line Links Gene Links