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Literature summary for 4.1.1.28 extracted from

  • Blechingberg, J.; Holm, I.E.; Johansen, M.G.; B?rglum, A.D.; Nielsen, A.L.
    Aromatic L-amino acid decarboxylase expression profiling and isoform detection in the developing porcine brain (2010), Brain Res., 1308, 1-13.
    View publication on PubMed

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
54000
-
deduced from amino acid sequence Sus scrofa

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-Dopa Sus scrofa
-
dopamine + CO2
-
?
L-Trp Sus scrofa
-
Tryptamine + CO2
-
?

Organism

Organism UniProt Comment Textmining
Sus scrofa
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
basal ganglion both the neuronal and the extraneuronal AADC mRNA isoforms are present at early brain developmental stages in the basal ganglia Sus scrofa
-
brain AADC expression in the developing pig brain is highly expressed in the basal ganglia and the brain stem regions, and also significantly expressed in the cortex, the hippocampus and the cerebellum Sus scrofa
-
brain cortex
-
Sus scrofa
-
brain stem both the neuronal and the extraneuronal AADC mRNA isoforms are present at early brain developmental stages in the brain stem Sus scrofa
-
cerebellum
-
Sus scrofa
-
hippocampus
-
Sus scrofa
-
liver
-
Sus scrofa
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-Dopa
-
Sus scrofa dopamine + CO2
-
?
L-Trp
-
Sus scrofa Tryptamine + CO2
-
?

Synonyms

Synonyms Comment Organism
AADC
-
Sus scrofa
AADC393 isoform Sus scrofa
AADC438 isoform Sus scrofa
AADC486 isoform Sus scrofa

Cofactor

Cofactor Comment Organism Structure
pyridoxal 5'-phosphate
-
Sus scrofa