EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
3.1.3.67 | phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase |
epithelial cell |
- |
694495 |
3.1.4.1 | phosphodiesterase I |
epithelial cell |
of airway |
649302 |
3.1.4.12 | sphingomyelin phosphodiesterase |
epithelial cell |
airway |
679682, 679685, 680143, 681259 |
3.1.4.17 | 3',5'-cyclic-nucleotide phosphodiesterase |
epithelial cell |
- |
716163 |
3.1.4.39 | alkylglycerophosphoethanolamine phosphodiesterase |
epithelial cell |
- |
650814, 714106 |
3.1.4.4 | phospholipase D |
epithelial cell |
- |
707550 |
3.1.4.4 | phospholipase D |
epithelial cell |
corneal |
707551 |
3.1.4.4 | phospholipase D |
epithelial cell |
primary, PLD1 |
715209 |
3.1.4.46 | glycerophosphodiester phosphodiesterase |
epithelial cell |
- |
-, 716983 |
3.1.6.12 | N-acetylgalactosamine-4-sulfatase |
epithelial cell |
- |
679286, 707573, 729810 |
3.1.6.12 | N-acetylgalactosamine-4-sulfatase |
epithelial cell |
brochial and renal |
707573 |
3.1.6.12 | N-acetylgalactosamine-4-sulfatase |
epithelial cell |
bronchial |
707081 |
3.1.6.12 | N-acetylgalactosamine-4-sulfatase |
epithelial cell |
bronchial epithelial cell |
752147 |
3.1.6.12 | N-acetylgalactosamine-4-sulfatase |
epithelial cell |
renal |
707573 |
3.1.6.8 | cerebroside-sulfatase |
epithelial cell |
highest activity of ASA |
675681 |
3.2.1.10 | oligo-1,6-glucosidase |
epithelial cell |
- |
666140, 677949, 717357 |
3.2.1.130 | glycoprotein endo-alpha-1,2-mannosidase |
epithelial cell |
- |
646729 |
3.2.1.166 | heparanase |
epithelial cell |
- |
731867 |
3.2.1.20 | alpha-glucosidase |
epithelial cell |
- |
717357 |
3.2.1.20 | alpha-glucosidase |
epithelial cell |
small-intestinal brush-border epithelial cells |
681471 |
3.2.1.3 | glucan 1,4-alpha-glucosidase |
epithelial cell |
- |
679741 |
3.2.1.3 | glucan 1,4-alpha-glucosidase |
epithelial cell |
small-intestinal brush-border epithelial cells |
681471 |
3.2.2.21 | DNA-3-methyladenine glycosylase II |
epithelial cell |
normal, malignant and immortalized breast cells |
646879 |
3.3.2.6 | leukotriene-A4 hydrolase |
epithelial cell |
- |
752450 |
3.3.2.6 | leukotriene-A4 hydrolase |
epithelial cell |
colonic |
753405 |
3.4.11.1 | leucyl aminopeptidase |
epithelial cell |
- |
664639 |
3.4.11.1 | leucyl aminopeptidase |
epithelial cell |
cecal epithelial cell as determined by in situ hybridisation |
731768 |
3.4.11.1 | leucyl aminopeptidase |
epithelial cell |
co-localizes with CsLAP1 to the intestinal epithelial cells of the parasite |
732471 |
3.4.11.1 | leucyl aminopeptidase |
epithelial cell |
co-localizes with CsLAP2 to the intestinal epithelial cells of the parasite |
732471 |
3.4.11.1 | leucyl aminopeptidase |
epithelial cell |
expressed in the cecal epithelial cells of adult parasites as shown by in situ hybridisation |
731768 |
3.4.11.1 | leucyl aminopeptidase |
epithelial cell |
from midgut |
680250 |
3.4.11.10 | bacterial leucyl aminopeptidase |
epithelial cell |
expressed in the cecal epithelial cells of adult parasites as shown by in situ hybridisation |
731768 |
3.4.11.2 | membrane alanyl aminopeptidase |
epithelial cell |
- |
663607, 665431, 666240, 698279 |
3.4.11.2 | membrane alanyl aminopeptidase |
epithelial cell |
the protein localizes to the apical side of posterior midgut epithelial cells of larva |
708731 |
3.4.11.3 | cystinyl aminopeptidase |
epithelial cell |
of hepato-biliary |
667811 |
3.4.14.2 | dipeptidyl-peptidase II |
epithelial cell |
of renal convoluted tubules, of uterine glands |
650796 |
3.4.14.5 | dipeptidyl-peptidase IV |
epithelial cell |
- |
677580, 695876, 703678 |
3.4.14.5 | dipeptidyl-peptidase IV |
epithelial cell |
DPP-IV is localized only in epithelial cells of vessels of the blood-brain barrier and on ependyma |
703784 |
3.4.15.1 | peptidyl-dipeptidase A |
epithelial cell |
- |
701190 |
3.4.15.1 | peptidyl-dipeptidase A |
epithelial cell |
cultured, corneal |
710024 |
3.4.15.1 | peptidyl-dipeptidase A |
epithelial cell |
membrane-bound form, surface of epithelial cells of epididymis and prostate |
755108 |
3.4.15.1 | peptidyl-dipeptidase A |
epithelial cell |
of pulmonary capillaries |
707126 |
3.4.17.12 | carboxypeptidase M |
epithelial cell |
- |
697395 |
3.4.17.12 | carboxypeptidase M |
epithelial cell |
columnar epithelial cell |
684055 |
3.4.19.12 | ubiquitinyl hydrolase 1 |
epithelial cell |
parietal epithelial cells of Bowman's capsules and some tubular epithelia in the kidney |
709664 |
3.4.19.12 | ubiquitinyl hydrolase 1 |
epithelial cell |
UCH-L3 is the predominant deubiquitinating enzyme in endosomal compartments of collecting duct epithelial cells |
680865 |
3.4.21.106 | hepsin |
epithelial cell |
- |
674067 |
3.4.21.109 | matriptase |
epithelial cell |
- |
651092, 683332, 683343, 695463, 695506, 696669, 696696, 696852, 698077, 698665, 698819, 731663 |
3.4.21.109 | matriptase |
epithelial cell |
basolateral sides |
671832 |
3.4.21.109 | matriptase |
epithelial cell |
bronchial epithelial cells |
732419 |
3.4.21.109 | matriptase |
epithelial cell |
is expressed in epithelial cells as a zymogen |
732309 |
3.4.21.109 | matriptase |
epithelial cell |
matriptase-dependent cell surface proteolysis in epithelial development and pathogenesis, overview |
683489 |
3.4.21.109 | matriptase |
epithelial cell |
matriptase-prostasin cascade |
683189 |
3.4.21.120 | oviductin |
epithelial cell |
luminal epithelial cells of uterus |
668865 |
3.4.21.122 | transmembrane protease serine 2 |
epithelial cell |
primary human bronchial epithelial cell and primary type II alveolar epithelial cell |
754559 |
3.4.21.122 | transmembrane protease serine 2 |
epithelial cell |
TMPRSS2 is expressed by epithelial cells at all sites examined in the aerodigestive tracts as well as by many endothelial cells |
755193 |
3.4.21.26 | prolyl oligopeptidase |
epithelial cell |
- |
683926 |
3.4.21.34 | plasma kallikrein |
epithelial cell |
prekallikrein expression |
653115 |
3.4.21.35 | tissue kallikrein |
epithelial cell |
secretory epithelial cells tf trachea, thyroid gland, mammary gland, salivary gland, jejunum, ileum, epididymis, seminal vesicle and urethra |
665230 |
3.4.21.37 | leukocyte elastase |
epithelial cell |
- |
708182, 708208 |
3.4.21.37 | leukocyte elastase |
epithelial cell |
primary small airway epithelial cells |
707080 |
3.4.21.39 | chymase |
epithelial cell |
- |
698854 |
3.4.21.4 | trypsin |
epithelial cell |
isoform trypsin IV is expressed in human renal epithelial cells and can increase epithelial sodium channel-mediated sodium transport in cultured human airway epithelial cells |
732138 |
3.4.21.5 | thrombin |
epithelial cell |
- |
717817 |
3.4.21.73 | u-Plasminogen activator |
epithelial cell |
- |
-, 707070, 707951 |
3.4.21.73 | u-Plasminogen activator |
epithelial cell |
A-549 alveolar epithelial cell cultured on a fibrin matrix, stimulation by interleukin 1beta results in increased levels of enzyme in culture supernatant |
670938 |
3.4.21.73 | u-Plasminogen activator |
epithelial cell |
gastric biopsy probes. uPA, uPA receptor and inhibitor PAI-1 are expressed in H+/K+ ATPase- and vesicular monoamine transporter 2-expressing cells. uPA is also expressed in pepsinogen- and uPA receptor-containing cells. In each case, expression is increased in response to Helicobacter pylori, and for uPA, but not the receptor or PAI-1, requires the virulence factor CagE. Helicobacter pylori also stimulates soluble and cell surface-bound uPA activity |
695475 |
3.4.21.73 | u-Plasminogen activator |
epithelial cell |
outermost epithelial cells of the hair follicle |
707287 |
3.4.21.73 | u-Plasminogen activator |
epithelial cell |
primary |
708237 |
3.4.21.76 | Myeloblastin |
epithelial cell |
inflamed oral epithelial cell |
683193 |
3.4.21.9 | enteropeptidase |
epithelial cell |
- |
732698 |
3.4.21.B25 | PACE4 proprotein convertase |
epithelial cell |
- |
717637 |
3.4.21.B41 | kallikrein 10 |
epithelial cell |
- |
667874 |
3.4.21.B43 | kallikrein 12 |
epithelial cell |
- |
731781 |
3.4.21.B45 | kallikrein 14 |
epithelial cell |
of normal bronchus |
691155 |
3.4.21.B6 | prostasin |
epithelial cell |
- |
-, 671262, 673905, 732131 |
3.4.21.B61 | transmembrane protease serine 11D |
epithelial cell |
- |
755193 |
3.4.22.1 | cathepsin B |
epithelial cell |
- |
696544 |
3.4.22.1 | cathepsin B |
epithelial cell |
oral |
699208 |
3.4.22.15 | cathepsin L |
epithelial cell |
- |
731095, 752853 |
3.4.22.27 | cathepsin S |
epithelial cell |
- |
-, 669716 |
3.4.22.34 | Legumain |
epithelial cell |
gut |
699882 |
3.4.22.38 | cathepsin K |
epithelial cell |
- |
697375, 708450 |
3.4.22.38 | cathepsin K |
epithelial cell |
primary type II alveolar epithelial cells |
-, 701180 |
3.4.22.43 | cathepsin V |
epithelial cell |
- |
669754 |
3.4.22.55 | caspase-2 |
epithelial cell |
- |
731596 |
3.4.22.56 | caspase-3 |
epithelial cell |
- |
697224, 699097 |
3.4.22.56 | caspase-3 |
epithelial cell |
active cleaved caspase-3 in epithelial cells of the intestine, quantitative immunohistochemical staining, overview |
698142 |
3.4.22.56 | caspase-3 |
epithelial cell |
epithelial acinar cells |
695951 |
3.4.22.61 | caspase-8 |
epithelial cell |
- |
699097 |
3.4.22.62 | caspase-9 |
epithelial cell |
- |
731215 |
3.4.22.64 | caspase-11 |
epithelial cell |
- |
731905 |
3.4.23.4 | chymosin |
epithelial cell |
- |
667435 |
3.4.24.17 | stromelysin 1 |
epithelial cell |
- |
734672 |
3.4.24.17 | stromelysin 1 |
epithelial cell |
gastric epithelial cell |
718271 |
3.4.24.18 | meprin A |
epithelial cell |
Madin-Darby canine kidney epithelial cells |
697872 |
3.4.24.23 | matrilysin |
epithelial cell |
MMP-7 expression analysis |
683362 |
3.4.24.23 | matrilysin |
epithelial cell |
predominantly expressed |
755014 |
3.4.24.23 | matrilysin |
epithelial cell |
primary airway epithelial cell air-liquid interface culture. Tissue inhibitor of metalloproteinase TIMP-1 and matrilysin co-localize and co-immunoprecipitate in wounded primary airway epithelial cultures. TIMP-1-deficient cultures migrate faster, and epithelial cells spread to a greater extent compared with wild-type cultures. TIMP-1 also inhibits matrilysin-mediated cell migration and spreading in vitro. In vivo, TIMP-1 deficiency enhances airway re-epithelialization after naphthalene injury. TIMP-1 and matrilysin co-localize in airway epithelial cells adjacent to the wound edge |
695448 |
3.4.24.23 | matrilysin |
epithelial cell |
pro-MMP-7 is diffusely distributed in epithelial cells of the endometrium, while the mature enzyme is located at the plasma membrane |
683345 |