Information on EC 3.4.22.61 - caspase-8

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EC Tree
     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.22 Cysteine endopeptidases
                3.4.22.61 caspase-8
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Word Map
The enzyme appears in viruses and cellular organisms
Reaction Schemes
strict requirement for Asp at position P1 and has a preferred cleavage sequence of (Leu/Asp/Val)-Glu-Thr-Asp-/-(Gly/Ser/Ala)
Synonyms
caspase-8, caspase 8, casp8, flice, cysteine protease caspase-8, cysteine aspartic acid-specific protease, apoptotic cysteine protease, flice/mach, fadd-like ice, cysteine aspartic acid protease 8, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
strict requirement for Asp at position P1 and has a preferred cleavage sequence of (Leu/Asp/Val)-Glu-Thr-Asp-/-(Gly/Ser/Ala)
show the reaction diagram
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