Application | Comment | Organism |
---|---|---|
diagnostics | caspase-3 activity is a marker for apoptosis in gut epithelium, leading to impairment of the gastrointestinal mucosal barrier, that contributes to progression of HIV infection, immunohistochemical staining of cleaved caspase-3, overview | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | active caspase-3 is involved in apoptosis in epithelial cells of the intestine | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
proteolytic modification | procaspase-3 is activated by cleavage to caspase-3 | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
epithelial cell | active cleaved caspase-3 in epithelial cells of the intestine, quantitative immunohistochemical staining, overview | Homo sapiens | - |
intestine | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | active caspase-3 is involved in apoptosis in epithelial cells of the intestine | Homo sapiens | ? | - |
? |