EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
2.7.11.24 | mitogen-activated protein kinase |
cerebral cortex |
- |
697804, 703574 |
2.7.11.26 | tau-protein kinase |
cerebral cortex |
- |
662124, 760847 |
2.7.11.26 | tau-protein kinase |
cerebral cortex |
cold-water stress-induced tau phosphorylation pattern |
661724 |
2.7.11.26 | tau-protein kinase |
cerebral cortex |
high expression |
760847 |
2.7.11.31 | [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase |
cerebral cortex |
- |
760259 |
2.7.12.2 | mitogen-activated protein kinase kinase |
cerebral cortex |
high expression level of MKK4 |
682214 |
2.7.12.2 | mitogen-activated protein kinase kinase |
cerebral cortex |
highest levels of expression |
682214 |
2.7.3.2 | creatine kinase |
cerebral cortex |
- |
-, 705501, 705502, 739050 |
2.7.3.2 | creatine kinase |
cerebral cortex |
in cerebral cortex creatine kinase activity is inhibited 6 and 12 h after renal ischemia. Only N-acetylcysteine or N-acetylcysteine plus deferoxamine are able to prevent the inhibition on the enzyme |
-, 689220 |
2.7.6.2 | thiamine diphosphokinase |
cerebral cortex |
- |
762503 |
2.7.8.11 | CDP-diacylglycerol-inositol 3-phosphatidyltransferase |
cerebral cortex |
- |
645316 |
2.7.9.3 | selenide, water dikinase |
cerebral cortex |
- |
762075 |
2.8.2.17 | chondroitin 6-sulfotransferase |
cerebral cortex |
- |
738897 |
2.8.2.23 | [heparan sulfate]-glucosamine 3-sulfotransferase 1 |
cerebral cortex |
- |
761164 |
2.8.2.23 | [heparan sulfate]-glucosamine 3-sulfotransferase 1 |
cerebral cortex |
high expression level |
761164 |
2.8.2.29 | [heparan sulfate]-glucosamine 3-sulfotransferase 2 |
cerebral cortex |
high expression level |
761164 |
2.8.2.5 | chondroitin 4-sulfotransferase |
cerebral cortex |
- |
695144 |
3.1.1.2 | arylesterase |
cerebral cortex |
- |
35206 |
3.1.1.23 | acylglycerol lipase |
cerebral cortex |
- |
650849, 653676 |
3.1.1.34 | lipoprotein lipase |
cerebral cortex |
- |
716346 |
3.1.1.4 | phospholipase A2 |
cerebral cortex |
- |
653367 |
3.1.1.4 | phospholipase A2 |
cerebral cortex |
distribution of sPLa2-IIe, sPLA2-V, and sPLA2-X is mainly neuronal with highest abundance in cerebral cortex and hippocampus. Enzymes are differentially induced by kainic acid |
666137 |
3.1.1.7 | acetylcholinesterase |
cerebral cortex |
- |
653365, 679180, 682110, 682902, 694391 |
3.1.1.8 | cholinesterase |
cerebral cortex |
- |
730237 |
3.1.2.2 | palmitoyl-CoA hydrolase |
cerebral cortex |
- |
646125, 646126, 646167 |
3.1.2.2 | palmitoyl-CoA hydrolase |
cerebral cortex |
brain-specific isozyme |
653187 |
3.1.2.20 | acyl-CoA hydrolase |
cerebral cortex |
- |
646125, 646126, 646167 |
3.1.3.16 | protein-serine/threonine phosphatase |
cerebral cortex |
- |
655140, 682117 |
3.1.3.41 | 4-nitrophenylphosphatase |
cerebral cortex |
- |
682284 |
3.1.3.43 | [pyruvate dehydrogenase (acetyl-transferring)]-phosphatase |
cerebral cortex |
high expression |
730476 |
3.1.3.48 | protein-tyrosine-phosphatase |
cerebral cortex |
- |
-, 750705 |
3.1.3.5 | 5'-nucleotidase |
cerebral cortex |
- |
679085, 682113, 692192 |
3.1.3.5 | 5'-nucleotidase |
cerebral cortex |
synaptosome |
707925 |
3.1.3.56 | inositol-polyphosphate 5-phosphatase |
cerebral cortex |
- |
646382 |
3.1.3.9 | glucose-6-phosphatase |
cerebral cortex |
- |
134945 |
3.1.4.11 | phosphoinositide phospholipase C |
cerebral cortex |
- |
653348, 667504 |
3.1.4.11 | phosphoinositide phospholipase C |
cerebral cortex |
expression of PLC delta2 |
649088 |
3.1.4.11 | phosphoinositide phospholipase C |
cerebral cortex |
PLC-beta1 is highly expressed in the cerebral cortex and hippocampus |
691473 |
3.1.4.11 | phosphoinositide phospholipase C |
cerebral cortex |
PLCeta2 is restricted to brain. PLCeta2 gradually increases during brain development. PLCeta2 is not detected in embryos. At 1 week after birth PLCeta2 is barely detected and expression is first observed at weeks after birth |
669369 |
3.1.4.17 | 3',5'-cyclic-nucleotide phosphodiesterase |
cerebral cortex |
external layer of |
670448 |
3.1.4.3 | phospholipase C |
cerebral cortex |
synaptosomes |
666222 |
3.1.4.35 | 3',5'-cyclic-GMP phosphodiesterase |
cerebral cortex |
- |
691558 |
3.1.4.4 | phospholipase D |
cerebral cortex |
PLD2 expression is observed in the marginal zone from the earliest stage and then declines and completely disappears by embryonic day 20 |
666455 |
3.1.4.4 | phospholipase D |
cerebral cortex |
synaptosomes |
666222 |
3.1.4.46 | glycerophosphodiester phosphodiesterase |
cerebral cortex |
- |
679873 |
3.1.4.53 | 3',5'-cyclic-AMP phosphodiesterase |
cerebral cortex |
- |
678086 |
3.1.4.54 | N-acetylphosphatidylethanolamine-hydrolysing phospholipase D |
cerebral cortex |
- |
707099 |
3.1.6.1 | arylsulfatase (type I) |
cerebral cortex |
activity increases gradually during development |
135532 |
3.1.6.1 | arylsulfatase (type I) |
cerebral cortex |
no significant changes in enzyme level upon feeding ethanol-containing Lieber-DeCarli liquid diet |
677433 |
3.1.6.8 | cerebroside-sulfatase |
cerebral cortex |
- |
677433 |
3.2.1.114 | mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase |
cerebral cortex |
- |
731972 |
3.2.1.207 | mannosyl-oligosaccharide alpha-1,3-glucosidase |
cerebral cortex |
- |
714910 |
3.2.1.207 | mannosyl-oligosaccharide alpha-1,3-glucosidase |
cerebral cortex |
high expression level |
745592 |
3.2.1.207 | mannosyl-oligosaccharide alpha-1,3-glucosidase |
cerebral cortex |
higher expression |
-, 732369 |
3.2.1.28 | alpha,alpha-trehalase |
cerebral cortex |
strong trehalase activity |
750882 |
3.2.1.52 | beta-N-acetylhexosaminidase |
cerebral cortex |
in affected cats with GM2 gangliosidosis, hexosaminidase beta-subunit mRNA levels are approximately 1.5times higher than normal, while beta-subunit protein levels are substantially reduced |
700234 |
3.3.2.7 | hepoxilin-epoxide hydrolase |
cerebral cortex |
- |
647025 |
3.4.11.1 | leucyl aminopeptidase |
cerebral cortex |
- |
95178, 95227 |
3.4.11.14 | cytosol alanyl aminopeptidase |
cerebral cortex |
- |
682118 |
3.4.11.3 | cystinyl aminopeptidase |
cerebral cortex |
- |
669637 |
3.4.11.4 | tripeptide aminopeptidase |
cerebral cortex |
- |
35936 |
3.4.11.6 | aminopeptidase B |
cerebral cortex |
- |
35972, 682114 |
3.4.14.10 | tripeptidyl-peptidase II |
cerebral cortex |
- |
647148, 664475, 665981 |
3.4.14.9 | tripeptidyl-peptidase I |
cerebral cortex |
- |
752408 |
3.4.16.2 | lysosomal Pro-Xaa carboxypeptidase |
cerebral cortex |
greatest level of signals are detected in the cerebral cortex with very strong labeling in the cingulate and piriform cortex. Other areas of the cortex show moderate signal intensity |
731564 |
3.4.17.1 | carboxypeptidase A |
cerebral cortex |
- |
667459, 668122 |
3.4.17.15 | carboxypeptidase A2 |
cerebral cortex |
- |
667459 |
3.4.17.21 | Glutamate carboxypeptidase II |
cerebral cortex |
cortical cells dissociated in cell culture |
656609 |
3.4.17.22 | metallocarboxypeptidase D |
cerebral cortex |
- |
28967 |
3.4.17.23 | angiotensin-converting enzyme 2 |
cerebral cortex |
- |
679707 |
3.4.17.23 | angiotensin-converting enzyme 2 |
cerebral cortex |
about 10% of the ACE2 gene expression in kidney cortex |
668896 |
3.4.18.1 | cathepsin X |
cerebral cortex |
- |
683448 |
3.4.18.1 | cathepsin X |
cerebral cortex |
of healthy individuals and Alzheimer patients |
683448 |
3.4.19.12 | ubiquitinyl hydrolase 1 |
cerebral cortex |
- |
666444 |
3.4.19.12 | ubiquitinyl hydrolase 1 |
cerebral cortex |
down-regulation of UCHL-1 mRNA and protein in dementia with Lewy bodies, either in pure forms not associated with Alzheimer disease, and in common forms, with accompanying Alzheimer disease changes, but not in Parkinson disease. UCHL-3 expression reduced in Parkinson disease and dementia with Lewy bodies |
666444 |
3.4.21.108 | HtrA2 peptidase |
cerebral cortex |
- |
697749 |
3.4.21.109 | matriptase |
cerebral cortex |
skin |
698819 |
3.4.21.122 | transmembrane protease serine 2 |
cerebral cortex |
immunoreactive cells are found in 3 days old but not in 1-month-old male rats |
753658 |
3.4.21.26 | prolyl oligopeptidase |
cerebral cortex |
- |
683344 |
3.4.21.26 | prolyl oligopeptidase |
cerebral cortex |
specific expression of POP in glutamatergic pyramidal neurons of the cerebral cortex, particularly in the primary motir and somatosensory cortices |
683708 |
3.4.21.34 | plasma kallikrein |
cerebral cortex |
prekallikrein expression |
653115 |
3.4.21.61 | Kexin |
cerebral cortex |
mild expression of PC1 and moderate expression of PC2. PC1 and PC2 in cerebral cortex colocalizes in pyramidal and non-pyramidal neurons with carboxypeptidase-E and somatostatin |
683932 |
3.4.21.68 | t-Plasminogen activator |
cerebral cortex |
- |
-, 718064, 732063 |
3.4.21.93 | Proprotein convertase 1 |
cerebral cortex |
- |
669904 |
3.4.21.93 | Proprotein convertase 1 |
cerebral cortex |
colocalization with somatostatin, carboxypeptidase-E and PC2 in pyramidal and non-pyramidal neurons. Colocalization with carboxypeptidase-E confined to pyramidal neurons of deeper layer. PC1 exhibits 26% colocalization with somatostatin and 34% with carboxypeptidase-E |
683932 |
3.4.21.94 | proprotein convertase 2 |
cerebral cortex |
colocalization with somatostatin, carboxypeptidase-E and PC1 in pyramidal and non-pyramidal neurons. PC2 exhibits 30% colocalization with somatostatin and 44% with carboxypeptidase-E |
683932 |
3.4.21.94 | proprotein convertase 2 |
cerebral cortex |
high PC2 protein content at early ischeic reperfusion hour, which decreases with reperfusion time |
709250 |
3.4.21.B42 | hippostasin |
cerebral cortex |
expression revealed by immunohistochemistry |
667873 |
3.4.22.1 | cathepsin B |
cerebral cortex |
- |
36638 |
3.4.22.27 | cathepsin S |
cerebral cortex |
- |
697041 |
3.4.22.49 | separase |
cerebral cortex |
highly expressed in human fetal cerebral cortex compared with adult |
681037 |
3.4.22.52 | calpain-1 |
cerebral cortex |
- |
643998, 680913 |
3.4.22.56 | caspase-3 |
cerebral cortex |
- |
699679 |
3.4.22.61 | caspase-8 |
cerebral cortex |
ipsilateral side |
697809 |
3.4.22.62 | caspase-9 |
cerebral cortex |
mitochondrial fraction of cerebral tissue, hypoxia-treated, classified into a normoxic group and a hypoxic group |
700460 |
3.4.22.62 | caspase-9 |
cerebral cortex |
of newborn piglet |
666462 |
3.4.22.62 | caspase-9 |
cerebral cortex |
of newborn piglets |
666456 |
3.4.22.B72 | SENP3 peptidase |
cerebral cortex |
- |
-, 731627 |
3.4.22.B72 | SENP3 peptidase |
cerebral cortex |
dynamic changes in SENP3 expression in the cerebral cortex and in its cellular localization in traumatic brain injury compared to normal, overview |
-, 731628 |
3.4.23.45 | memapsin 1 |
cerebral cortex |
- |
638899, 638903 |