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Literature summary for 3.2.1.114 extracted from
- Effect of swainsonine in Oxytropis kansuensis on Golgi alpha-mannosidase II expression in the brain tissues of Sprague-Dawley rats (2014), J. Agric. Food Chem., 62, 7407-7412.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| swainsonine | - |
Rattus norvegicus |  |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| Golgi apparatus | - |
Rattus norvegicus | 5794 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | the enzyme is lowly expressed in the molecular layer of the cerebral cortex and hippocampal layers, and highly expressed in other areas of the brain | Rattus norvegicus | - |
| cerebellum | - |
Rattus norvegicus | - |
| cerebral cortex | - |
Rattus norvegicus | - |
| hippocampus | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 2,4-dinitrophenyl alpha-D-mannoside + H2O | - |
Rattus norvegicus | 2,4-dinitrophenol + alpha-D-mannose | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Golgi alpha-mannosidase II | - |
Rattus norvegicus |
| MAN2A1 | - |
Rattus norvegicus |
Expression
| Organism | Comment | Expression |
|---|---|---|
| Rattus norvegicus | the expression of mRNA is inhibited in cerebral and cerebellar tissues by swainsonine in Oxytropis kansuensis | down |
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Release 2023.1 (January 2023)
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