EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
1.1.1.10 | L-xylulose reductase |
MOLT-4 cell |
expression levels of L-xylulose reductase and its mRNA in the T lymphoma cells are markedly enhanced after the exposure to 9,10-phenanthrenequinone, and the induction is completely abolished by the ROS scavengers. L-Xylulose reductase is upregulated in the earlier step of the apoptosis and deteriorates the apoptotic signaling through the generation of ROS by the redox cycling of 9,10-phenanthrenequinone |
686877 |
1.1.1.205 | IMP dehydrogenase |
MOLT-4 cell |
leukemia cell |
690045 |
1.13.11.34 | arachidonate 5-lipoxygenase |
MOLT-4 cell |
- |
687058 |
1.4.3.5 | pyridoxal 5'-phosphate synthase |
MOLT-4 cell |
8.1% of the activity in liver |
655483 |
1.7.1.7 | GMP reductase |
MOLT-4 cell |
- |
659550 |
1.8.4.12 | peptide-methionine (R)-S-oxide reductase |
MOLT-4 cell |
control and stably overexpressing MsrA (from rat) and MsrB2 (from human). Zinc treatment has a pro-antioxidant effect in MOLT-4 cells by positively modulating the activity of the Msr enzymes. Overexpression of the Msr enzymes, due to their antioxidant properties, counteracts the pro-oxidant effects of zinc treatment, which lead to a cellular protection against protein oxidative damage and cell death, by reducing the production of reactive oxygen species |
684499 |
1.8.4.12 | peptide-methionine (R)-S-oxide reductase |
MOLT-4 cell |
overexpression of human methionine sulfoxide reductase B2 in mitochondria of acute T-lymphoblastic leukemia MOLT-4 cell line, in which methionine sulfoxide reductase A is missing |
687720 |
2.1.1.67 | thiopurine S-methyltransferase |
MOLT-4 cell |
- |
733775 |
2.3.1.147 | glycerophospholipid arachidonoyl-transferase (CoA-independent) |
MOLT-4 cell |
- |
676922 |
2.4.1.143 | alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase |
MOLT-4 cell |
- |
658123 |
2.4.1.144 | beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase |
MOLT-4 cell |
- |
658123 |
2.4.1.145 | alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase |
MOLT-4 cell |
high activity |
658123 |
2.4.1.152 | 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase |
MOLT-4 cell |
- |
639528 |
2.4.1.155 | alpha-1,6-mannosyl-glycoprotein 6-beta-N-acetylglucosaminyltransferase |
MOLT-4 cell |
- |
658123 |
2.4.1.90 | N-acetyllactosamine synthase |
MOLT-4 cell |
T cell leukemia cell line |
658123 |
2.4.2.28 | S-methyl-5'-thioadenosine phosphorylase |
MOLT-4 cell |
- |
637548 |
2.7.1.113 | deoxyguanosine kinase |
MOLT-4 cell |
- |
671801 |
2.7.1.113 | deoxyguanosine kinase |
MOLT-4 cell |
3fold increase when cells start to proliferate |
671801 |
2.7.1.153 | phosphatidylinositol-4,5-bisphosphate 3-kinase |
MOLT-4 cell |
- |
393230, 587104, 707979 |
2.7.1.74 | deoxycytidine kinase |
MOLT-4 cell |
- |
641941, 641942, 641946, 641967 |
2.7.1.74 | deoxycytidine kinase |
MOLT-4 cell |
activity increases within 36 h of growth compared to resting cells |
676245 |
2.7.1.74 | deoxycytidine kinase |
MOLT-4 cell |
enzyme activity increases up to 3fold when cells start to proliferate |
671801 |
2.7.11.1 | non-specific serine/threonine protein kinase |
MOLT-4 cell |
- |
694488 |
2.7.11.10 | IkappaB kinase |
MOLT-4 cell |
- |
722826 |
2.7.11.15 | beta-adrenergic-receptor kinase |
MOLT-4 cell |
high expression of beta-ARK 1 |
490989 |
2.7.11.25 | mitogen-activated protein kinase kinase kinase |
MOLT-4 cell |
mutated A-Raf |
682213 |
2.7.4.14 | UMP/CMP kinase |
MOLT-4 cell |
lymphoblastic leukemia cell |
645160 |
2.7.4.14 | UMP/CMP kinase |
MOLT-4 cell |
lymphoblastic leukemia cell line |
693063 |
3.1.3.16 | protein-serine/threonine phosphatase |
MOLT-4 cell |
a T-cell lymphoblastic leukemia cell line |
698767 |
3.2.1.166 | heparanase |
MOLT-4 cell |
- |
732954 |
3.4.11.1 | leucyl aminopeptidase |
MOLT-4 cell |
- |
665925 |
3.4.11.6 | aminopeptidase B |
MOLT-4 cell |
T-cell line |
665109, 666799 |
3.4.22.52 | calpain-1 |
MOLT-4 cell |
- |
718111 |
3.4.22.56 | caspase-3 |
MOLT-4 cell |
- |
647628 |
3.4.22.60 | caspase-7 |
MOLT-4 cell |
- |
668912 |
3.4.22.62 | caspase-9 |
MOLT-4 cell |
intact protein p53 |
698357 |
3.4.24.81 | ADAM10 endopeptidase |
MOLT-4 cell |
- |
720160 |
3.6.1.13 | ADP-ribose diphosphatase |
MOLT-4 cell |
- |
655991 |
4.2.3.12 | 6-pyruvoyltetrahydropterin synthase |
MOLT-4 cell |
acute lymphoblastic leukemia cell line, 65% homology with rat enzyme |
648559 |
5.6.2.1 | DNA topoisomerase |
MOLT-4 cell |
leukemia cell line |
693543 |
5.6.2.2 | DNA topoisomerase (ATP-hydrolysing) |
MOLT-4 cell |
- |
681905 |
6.1.1.20 | phenylalanine-tRNA ligase |
MOLT-4 cell |
lymphoblastic leukemia cell line |
649540 |
6.3.1.1 | aspartate-ammonia ligase |
MOLT-4 cell |
leukemia-derived camcer cell line |
693874 |
6.3.1.4 | aspartate-ammonia ligase (ADP-forming) |
MOLT-4 cell |
leukemia-derived cancer cell line |
693874 |
6.3.5.4 | asparagine synthase (glutamine-hydrolysing) |
MOLT-4 cell |
- |
671350, 693874 |
7.4.2.14 | ABC-type antigen peptide transporter |
MOLT-4 cell |
- |
762296 |