Activating Compound | Comment | Organism | Structure |
---|---|---|---|
cytolethal distending toxin | from Actinobacillus actinomycetemcomitans | Homo sapiens |
Application | Comment | Organism |
---|---|---|
medicine | Actinobacillus actinomycetemcomitans cytolethal distending toxin acts as an immunosuppressive factor, it possesses the ability to induce human T-cell apoptosis through activation of caspase-7 | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Ac-DEVD-CHO | - |
Homo sapiens | |
AC-DQTD-CHO | - |
Homo sapiens | |
Ac-Val-Ala-Asp-fluoromethylketone | - |
Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
JURKAT cell | - |
Homo sapiens | - |
MOLT-4 cell | - |
Homo sapiens | - |
T-lymphocyte | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Ac-DEVD-7-amido-4-methylcoumarin + H2O | - |
Homo sapiens | Ac-DEVD + 7-amino-4-methylcoumarin | - |
? | |
Ac-DQTD-7-amido-4-methylcoumarin + H2O | - |
Homo sapiens | Ac-DQTD + 7-amino-4-methylcoumarin | - |
? |