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Literature summary for 2.3.1.147 extracted from
- Inhibitors of arachidonic acid metabolism act synergistically to signal apoptosis in neoplastic cells (2005), Prostaglandins Leukot. Essent. Fatty Acids, 73, 463-474.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| NS-398 | enzyme inhibition in cancer cell has an anti-carcinogenic effect and induces accumulation of unesterified arachidonic acid | Homo sapiens |  |
| PLT-98625 | enzyme inhibition in cancer cell has an anti-carcinogenic effect and induces accumulation of unesterified arachidonic acid | Homo sapiens | |
| Triacsin C | enzyme inhibition in cancer cell has an anti-carcinogenic effect and induces accumulation of unesterified arachidonic acid | Homo sapiens | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Homo sapiens | the enzyme is involved in the control of intracellular arachidonic acid levels, enzyme inhibition in cancer cell has an anti-carcinogenic effect and induces accumulation of unesterified arachidonic acid, overview | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| HCT-116 cell | - |
Homo sapiens | - |
| HeLa cell | - |
Homo sapiens | - |
| HT-29 cell | - |
Homo sapiens | - |
| MDA-MB-231 cell | - |
Homo sapiens | - |
| MOLT-4 cell | - |
Homo sapiens | - |
| SK-MES-1 cell | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | the enzyme is involved in the control of intracellular arachidonic acid levels, enzyme inhibition in cancer cell has an anti-carcinogenic effect and induces accumulation of unesterified arachidonic acid, overview | Homo sapiens | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| CoA-IT | - |
Homo sapiens |
| Coenzyme A-independent transacylase | - |
Homo sapiens |
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