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Literature summary for 2.3.1.147 extracted from

  • Monjazeb, A.M.; High, K.P.; Koumenis, C.; Chilton, F.H.
    Inhibitors of arachidonic acid metabolism act synergistically to signal apoptosis in neoplastic cells (2005), Prostaglandins Leukot. Essent. Fatty Acids, 73, 463-474.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
NS-398 enzyme inhibition in cancer cell has an anti-carcinogenic effect and induces accumulation of unesterified arachidonic acid Homo sapiens
PLT-98625 enzyme inhibition in cancer cell has an anti-carcinogenic effect and induces accumulation of unesterified arachidonic acid Homo sapiens
Triacsin C enzyme inhibition in cancer cell has an anti-carcinogenic effect and induces accumulation of unesterified arachidonic acid Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens the enzyme is involved in the control of intracellular arachidonic acid levels, enzyme inhibition in cancer cell has an anti-carcinogenic effect and induces accumulation of unesterified arachidonic acid, overview ?
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?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
HCT-116 cell
-
Homo sapiens
-
HeLa cell
-
Homo sapiens
-
HT-29 cell
-
Homo sapiens
-
MDA-MB-231 cell
-
Homo sapiens
-
MOLT-4 cell
-
Homo sapiens
-
SK-MES-1 cell
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the enzyme is involved in the control of intracellular arachidonic acid levels, enzyme inhibition in cancer cell has an anti-carcinogenic effect and induces accumulation of unesterified arachidonic acid, overview Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
CoA-IT
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Homo sapiens
Coenzyme A-independent transacylase
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Homo sapiens