Application | Comment | Organism |
---|---|---|
synthesis | it is necessary to select appropriate host cell lines according to their glycosyltransferases activity balance to produce glycoproteins with an objective sugar chain structure. The descibed method of grouping cell lines according to their glycosyltransferases activity balance is useful to select appropriate host cells | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
UDP-N-acetyl-D-glucosamine + 3-(2-[N-acetyl-beta-D-glucosaminyl]-alpha-D-mannosyl)-beta-D-mannosyl-R | Homo sapiens | the enzyme is involved in the branch formation of Asn-linked sugar chains | UDP + 3-(2,4-bis[N-acetyl-beta-D-glucosaminyl]-alpha-D-mannosyl)-beta-D-mannosyl-R | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
A-549 cell | low activity | Homo sapiens | - |
BALL-1 cell | - |
Homo sapiens | - |
BeWo cell | high activity | Homo sapiens | - |
Caco-2 cell | high activity | Homo sapiens | - |
EoL-1 cell | low activity | Homo sapiens | - |
HeLa-S3 cell | low activity | Homo sapiens | - |
Hep-G2 cell | high activity | Homo sapiens | - |
HMCB cell | low activity | Homo sapiens | - |
HuO-3N1 cell | low activity | Homo sapiens | - |
KU-812 cell | - |
Homo sapiens | - |
KU-812 cell | low activity | Homo sapiens | - |
MOLT-4 cell | high activity | Homo sapiens | - |
NAMALWA cell | - |
Homo sapiens | - |
OS-RC-2 cell | - |
Homo sapiens | - |
THP-1 cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
UDP-N-acetyl-D-glucosamine + 3-(2-[N-acetyl-beta-D-glucosaminyl]-alpha-D-mannosyl)-beta-D-mannosyl-R | the enzyme is involved in the branch formation of Asn-linked sugar chains | Homo sapiens | UDP + 3-(2,4-bis[N-acetyl-beta-D-glucosaminyl]-alpha-D-mannosyl)-beta-D-mannosyl-R | - |
? |
Synonyms | Comment | Organism |
---|---|---|
GlcNAcTase-IV | - |
Homo sapiens |
N-acetylglucosaminyltransferase-IV | - |
Homo sapiens |