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Information on EC 2.4.1.143 - alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase

for references in articles please use BRENDA:EC2.4.1.143
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IUBMB Comments
R represents the remainder of the N-linked oligosaccharide in the glycoprotein acceptor. Note that this enzyme acts after N-acetylglucosaminyltransferase I but before N-acetylglucosaminyltransferases III, IV, V and VI (click here for diagram).
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Word Map
The enzyme appears in viruses and cellular organisms
Synonyms
n-acetylglucosaminyltransferase ii, gnt ii, glcnac-t ii, gnt-ii, gnt ii-a, gnt ii-b, n-acetylglucosaminyltransferase-ii, ttv/dext1, acetylglucosaminyltransferase ii, alpha-1,6-mannosyl-glycoprotein beta-1,2-n-acetylglucosaminyltransferase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
UDP-N-acetyl-alpha-D-glucosamine + beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-N-Asn-[protein] = UDP + beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-N-Asn-[protein]
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