Reference on EC 7.6.2.1 - P-type phospholipid transporter and Organism(s) Homo sapiens
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AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Vermeulen, W.P.; Briede, J.J.; Roelofsen, B.
Manipulation of the phosphatidylethanolamine pool in the human red cell membrane affects its Mg-ATPase activity
Mol. Membr. Biol.
13
95-102
1996
Homo sapiens
Morris, M.B.; Auland, M.E.; Xu, Y.H.; Roufogalis, B.D.
Characterization of the Mg2+-ATPase activity of the human erythrocyte membrane
Biochem. Mol. Biol. Int.
31
823-832
1993
Homo sapiens
Beleznay, Z.; Zachowski, A.; Devaux, P.F.; Ott, P.
Characterization of the correlation between ATP-dependent aminophospholipid translocation and Mg2+-ATPase activity in red blood cell membranes
Eur. J. Biochem.
243
58-65
1997
Homo sapiens
Bartosz, G.; Batosz, M.; Sokal, A.; Gebicki, J.M.
Stimulation of erythrocyte membrane Mg2+-ATPase activity by dinitrophenol and other membrane-disturbing agents
Biochem. Mol. Biol. Int.
34
521-529
1994
Homo sapiens
Daleke, D.L.; Lyles, J.V.
Identification and purification of aminophospholipid flippases
Biochim. Biophys. Acta
1486
108-127
2000
Bos taurus, Homo sapiens
Beleznay, Z.; Zachowski, A.; Devaux, P.F.; Navazo, M.P.; Ott, P.
ATP-dependent aminophospholipid translocation in erythrocyte vesicles: stoichiometry of transport
Biochemistry
32
3146-3152
1993
Homo sapiens
Devaux, P.F.; Zachowski, A.; Morrot, G.; Cribier, S.; Fellmann, P.; Geldwerth, D.; Bitbol, M.; Herve, P.
Control of the transmembrane phospholipid distribution in eukaryotic cells by aminophospholipid translocase
Biotechnol. Appl. Biochem.
12
517-522
1990
Bos taurus, Cavia porcellus, Homo sapiens, Rattus norvegicus, Sus scrofa
Auland, M.E.; Morris, M.B.; Roufogalis, B.D.
Separation and characterization of two Mg2+-ATpase activities from human erythrocyte membrane
Arch. Biochem. Biophys.
312
272-277
1994
Homo sapiens
Auland, M.E.; Roufogalis, B.D.; Devaux, P.F.; Zachowski, A.
Reconstitution of ATP-dependent aminophospholipid translocation in proteoliposomes
Proc. Natl. Acad. Sci. USA
91
10938-10942
1994
Homo sapiens
Middelkoop, E.; van der Hoek, E.E.; Bevers, E.M.; Comfurius, P.; Slotboom, A.J.; op den Kamp, J.A.F.; Lubin, B.H.; Zwaal, R.F.A.; Roelofsen, B.
Involvement of ATP-dependent aminophospholipid translocation in maintaining phospholipid asymmetry in diamide-treated human erythrocytes
Biochim. Biophys. Acta
981
151-160
1989
Homo sapiens
Connor, J.; Schroit, A.J.
Transbilayer, movement of phosphatidylserine in erythrocytes. Inhibitors of aminophospholipid transport block the association of photolabeled lipid to its transporter
Biochim. Biophys. Acta
1066
37-42
1991
Homo sapiens
Herzing, L.B.; Kim, S.J.; Cook, E.H., Jr.; Ledbetter, D.H.
The human aminophospholipid-transporting ATPase gene ATP10C maps adjacent to UBE3A and exhibits similar imprinted expression
Am. J. Hum. Genet.
68
1501-1505
2001
Homo sapiens (O60312)
Wolfs, J.L.; Comfurius, P.; Rasmussen, J.T.; Keuren, J.F.; Lindhout, T.; Zwaal, R.F.; Bevers, E.M.
Activated scramblase and inhibited aminophospholipid translocase cause phosphatidylserine exposure in a distinct platelet fraction
Cell. Mol. Life Sci.
62
1514-1525
2005
Homo sapiens
Devaux, P.F.; Lopez-MOntero, I.; Bryde, S.
Proteins involved in lipid translocation in eukaryotic cells
Chem. Phys. Lipids
141
119-132
2006
Bos taurus, Saccharomyces cerevisiae, Homo sapiens, Leishmania infantum, Rattus norvegicus
Camberg, J.L.; Sandkvist, M.
Molecular analysis of the Vibrio cholerae type II secretion ATPase EpsE
J. Bacteriol.
187
249-256
2005
Homo sapiens
Verhoeven, A.J.; Hilarius, P.M.; Dekkers, D.W.; Lagerberg, J.W.; de Korte, D.
Prolonged storage of red blood cells affects aminophospholipid translocase activity
Vox Sang.
91
244-251
2006
Homo sapiens
Sahu, S.K.; Gummadi, S.N.; Manoj, N.; Aradhyam, G.K.
Phospholipid scramblases: an overview
Arch. Biochem. Biophys.
462
103-114
2007
Homo sapiens (O15162), Homo sapiens (Q9NRQ2), Homo sapiens (Q9NRY6), Homo sapiens (Q9NRY7), Mus musculus (P58196), Mus musculus (Q9JJ00), Caenorhabditis elegans (Q21318)
Smriti, T.; Nemergut, E.C.; Daleke, D.L.
ATP-dependent transport of phosphatidylserine analogues in human erythrocytes
Biochemistry
46
2249-2259
2007
Homo sapiens
Liu, J.; Epand, R.F.; Durrant, D.; Grossman, D.; Chi, N.W.; Epand, R.M.; Lee, R.M.
Role of phospholipid scramblase 3 in the regulation of tumor necrosis factor-alpha-induced apoptosis
Biochemistry
47
4518-4529
2008
Homo sapiens
Razmara, M.; Hu, H.; Masquelier, M.; Li, N.
Glycoprotein IIb/IIIa blockade inhibits platelet aminophospholipid exposure by potentiating translocase and attenuating scramblase activity
Cell. Mol. Life Sci.
64
999-1008
2007
Homo sapiens
Regev, R.; Katzir, H.; Yeheskely-Hayon, D.; Eytan, G.D.
Modulation of P-glycoprotein-mediated multidrug resistance by acceleration of passive drug permeation across the plasma membrane
FEBS J.
274
6204-6214
2007
Homo sapiens (O43520)
Morita, S.Y.; Kobayashi, A.; Takanezawa, Y.; Kioka, N.; Handa, T.; Arai, H.; Matsuo, M.; Ueda, K.
Bile salt-dependent efflux of cellular phospholipids mediated by ATP binding cassette protein B4
Hepatology
46
188-199
2007
Homo sapiens
Tyurina, Y.Y.; Basova, L.V.; Konduru, N.V.; Tyurin, V.A.; Potapovich, A.I.; Cai, P.; Bayir, H.; Stoyanovsky, D.; Pitt, B.R.; Shvedova, A.A.; Fadeel, B.; Kagan, V.E.
Nitrosative stress inhibits the aminophospholipid translocase resulting in phosphatidylserine externalization and macrophage engulfment: implications for the resolution of inflammation
J. Biol. Chem.
282
8498-8509
2007
Homo sapiens
Leung, R.; Gwozdz, A.M.; Wang, H.; Bang, K.W.; Packham, M.A.; Freedman, J.; Rand, M.L.
Persistence of procoagulant surface expression on activated human platelets: involvement of apoptosis and aminophospholipid translocase activity
J. Thromb. Haemost.
5
560-570
2007
Homo sapiens
Wyles, J.P.; Wu, Z.; Mirski, S.E.; Cole, S.P.
Nuclear interactions of topoisomerase II alpha and beta with phospholipid scramblase 1
Nucleic Acids Res.
35
4076-4085
2007
Homo sapiens
Masuda, M.; Nakai, E.; Mizutani, T.
Study of oxidized lipids as endogenous substrates of P-gp (ABCB1)
Drug Metab. Lett.
2
238-244
2008
Homo sapiens
Barta, C.A.; Sachs-Barrable, K.; Feng, F.; Wasan, K.M.
Effects of monoglycerides on P-glycoprotein: modulation of the activity and expression in Caco-2 cell monolayers
Mol. Pharm.
5
863-875
2008
Homo sapiens
Barber, L.A.; Palascak, M.B.; Joiner, C.H.; Franco, R.S.
Aminophospholipid translocase and phospholipid scramblase activities in sickle erythrocyte subpopulations
Br. J. Haematol.
146
447-455
2009
Homo sapiens
Coleman, J.A.; Kwok, M.C.; Molday, R.S.
Localization, purification, and functional reconstitution of the P4-ATPase Atp8a2, a phosphatidylserine flippase in photoreceptor disc membranes
J. Biol. Chem.
284
32670-32679
2009
Bos taurus (C7EXK4), Mus musculus (P98200), Homo sapiens (Q9NTI2)
Sebastian, T.T.; Baldridge, R.D.; Xu, P.; Graham, T.R.
Phospholipid flippases: Building asymmetric membranes and transport vesicles
Biochim. Biophys. Acta
1821
1068-1077
2012
Arabidopsis thaliana, Saccharomyces cerevisiae, Saccharomyces cerevisiae (P32660), Saccharomyces cerevisiae (P39524), Saccharomyces cerevisiae (Q12674), Homo sapiens, Caenorhabditis elegans (C7U324), Caenorhabditis elegans (G5EBH1), Caenorhabditis elegans (O18182), Caenorhabditis elegans (P91203), Caenorhabditis elegans (Q7YXV5)
van der Velden, L.M.; Wichers, C.G.; van Breevoort, A.E.; Coleman, J.A.; Molday, R.S.; Berger, R.; Klomp, L.W.; van de Graaf, S.F.
Heteromeric interactions required for abundance and subcellular localization of human CDC50 proteins and class 1 P4-ATPases
J. Biol. Chem.
285
40088-40096
2010
Homo sapiens (Q9Y2Q0), Homo sapiens
Takatsu, H.; Baba, K.; Shima, T.; Umino, H.; Kato, U.; Umeda, M.; Nakayama, K.; Shin, H.W.
ATP9B, a P4-ATPase (a putative aminophospholipid translocase), localizes to the trans-Golgi network in a CDC50 protein-independent manner
J. Biol. Chem.
286
38159-38167
2011
Homo sapiens
Smith, B.A.; ONeil, E.J.; Lampkins, A.J.; Johnson, J.R.; Lee, J.J.; Cole, E.L.; Smith, B.D.
Evaluation of fluorescent phosphatidylserine substrates for the aminophospholipid flippase in mammalian cells
J. Fluoresc.
22
93-101
2012
Cricetulus griseus, Homo sapiens
Kim, J.E.; Han, M.; Hanl, K.S.; Kim, H.K.
Vitamin E inhibition on platelet procoagulant activity: involvement of aminophospholipid translocase activity
Thromb. Res.
127
435-442
2011
Homo sapiens
Lee, S.; Uchida, Y.; Wang, J.; Matsudaira, T.; Nakagawa, T.; Kishimoto, T.; Mukai, K.; Inaba, T.; Kobayashi, T.; Molday, R.S.; Taguchi, T.; Arai, H.
Transport through recycling endosomes requires EHD1 recruitment by a phosphatidylserine translocase
EMBO J.
34
669-688
2015
Homo sapiens (Q9NTI2), Homo sapiens (Q9Y2Q0)
Onat, O.E.; Gulsuner, S.; Bilguvar, K.; Nazli Basak, A.; Topaloglu, H.; Tan, M.; Tan, U.; Gunel, M.; Ozcelik, T.
Missense mutation in the ATPase, aminophospholipid transporter protein ATP8A2 is associated with cerebellar atrophy and quadrupedal locomotion
Eur. J. Hum. Genet.
21
281-285
2013
Homo sapiens (Q9NTI2), Homo sapiens
Kleinegris, M.C.; Koek, G.H.; Mast, K.; Mestrom, E.H.; Wolfs, J.L.; Bevers, E.M.
Ribavirin-induced externalization of phosphatidylserine in erythrocytes is predominantly caused by inhibition of aminophospholipid translocase activity
Eur. J. Pharmacol.
693
1-6
2012
Homo sapiens
Takatsu, H.; Tanaka, G.; Segawa, K.; Suzuki, J.; Nagata, S.; Nakayama, K.; Shin, H.W.
Phospholipid flippase activities and substrate specificities of human type IV P-type ATPases localized to the plasma membrane
J. Biol. Chem.
289
33543-33556
2014
Homo sapiens (O43520), Homo sapiens (P98196), Homo sapiens (P98198), Homo sapiens (Q8NB49), Homo sapiens
Naito, T.; Takatsu, H.; Miyano, R.; Takada, N.; Nakayama, K.; Shin, H.W.
Phospholipid flippase ATP10A translocates phosphatidylcholine and is involved in plasma membrane dynamics
J. Biol. Chem.
290
15004-15017
2015
Homo sapiens (O60312), Homo sapiens (O94823), Homo sapiens (Q9P241)
Ansari, I.U.; Longacre, M.J.; Paulusma, C.C.; Stoker, S.W.; Kendrick, M.A.; MacDonald, M.J.
Characterization of P4 ATPase phospholipid translocases (flippases) in human and rat pancreatic beta cells: their gene silencing inhibits insulin secretion
J. Biol. Chem.
290
23110-23123
2015
Rattus norvegicus (D4AA47), Homo sapiens (O43520), Homo sapiens (P98198), Homo sapiens (Q2NLD0), Homo sapiens
van der Mark, V.A.; de Jonge, H.R.; Chang, J.C.; Ho-Mok, K.S.; Duijst, S.; Vidovic, D.; Carlon, M.S.; Oude Elferink, R.P.; Paulusma, C.C.
The phospholipid flippase ATP8B1 mediates apical localization of the cystic fibrosis transmembrane regulator
Biochim. Biophys. Acta
1863
2280-2288
2016
Homo sapiens (O43520), Homo sapiens
Takada, N.; Naito, T.; Inoue, T.; Nakayama, K.; Takatsu, H.; Shin, H.W.
Phospholipid-flipping activity of P4-ATPase drives membrane curvature
EMBO J.
37
pii: e97705
2018
Homo sapiens (O60312)
Tanaka, Y.; Ono, N.; Shima, T.; Tanaka, G.; Katoh, Y.; Nakayama, K.; Takatsu, H.; Shin, H.W.
The phospholipid flippase ATP9A is required for the recycling pathway from the endosomes to the plasma membrane
Mol. Biol. Cell
27
3883-3893
2016
Homo sapiens (O75110), Homo sapiens
Takatsu, H.; Takayama, M.; Naito, T.; Takada, N.; Tsumagari, K.; Ishihama, Y.; Nakayama, K.; Shin, H.W.
Phospholipid flippase ATP11C is endocytosed and downregulated following Ca2+-mediated protein kinase C activation
Nat. Commun.
8
1423
2017
Homo sapiens (Q8NB49)
