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Literature summary for 7.6.2.1 extracted from
- Characterization of the Mg2+-ATPase activity of the human erythrocyte membrane (1993), Biochem. Mol. Biol. Int., 31, 823-832.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| ATP | biphasic activation, K0.5 = 0.02 mM and 0.4 mM | Homo sapiens |  |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Cd2+ | - |
Homo sapiens | |
| La3+ | - |
Homo sapiens | |
| vanadate | biphasic inhibition | Homo sapiens | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| plasma membrane | - |
Homo sapiens | 5886 | - |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | required | Homo sapiens | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| erythrocyte | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + H2O | translocation of the aminophospholipids, phosphatidylserine and phosphatidylethanolamine, from the outer leaflet to the inner leaflet of the lipid bilayer, enzyme is involved in ATP-dependent erythrocyte shape change | Homo sapiens | ADP + phosphate | - |
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