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Literature summary for 7.6.2.1 extracted from

  • Kim, J.E.; Han, M.; Hanl, K.S.; Kim, H.K.
    Vitamin E inhibition on platelet procoagulant activity: involvement of aminophospholipid translocase activity (2011), Thromb. Res., 127, 435-442.
    View publication on PubMed
Search for more literature for 7.6.2.1

Activating Compound

Activating Compound Comment Organism Structure
additional information APLT activity is increased by vitamin E in a dose-dependent manner Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
plasma membrane
-
 Homo sapiens 5886
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
blood platelet
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information usage of 1-palmitoyl-2-[6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]caproyl]-sn-glycero-3-phosphatidylserine as transport substrate in assays of translocated from the outer to the inner membrane leaflet Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
APLT
-
 Homo sapiens

General Information

General Information Comment Organism
physiological function aminophospholipid translocase can transport phosphatidylserine from the outer to the inner membrane leaflet. The enzyme is involved in the inhibition effects of vitamin E on platelet aggregation, vitamin E inhibits phosphatidylserine exposure in both phorbol 12-myristate 13-acetate- and thrombin-stimulated platelets Homo sapiens