Literature summary for 7.6.2.1 extracted from

Takatsu, H.; Takayama, M.; Naito, T.; Takada, N.; Tsumagari, K.; Ishihama, Y.; Nakayama, K.; Shin, H.W.
Phospholipid flippase ATP11C is endocytosed and downregulated following Ca2+-mediated protein kinase C activation (2017), Nat. Commun., 8, 1423 .

Search for more literature for 7.6.2.1

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
plasma membrane	-	Homo sapiens	5886	-

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
ATP + H2O + phosphatidylethanolamine[side 1]	Homo sapiens	-	ADP + phosphate + phosphatidylethanolamine[side 2]	-	?
ATP + H2O + phosphatidylserine[side 1]	Homo sapiens	-	ADP + phosphate + phosphatidylserine[side 2]	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	Q8NB49	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
HeLa cell	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + H2O + phosphatidylethanolamine[side 1]	-	Homo sapiens	ADP + phosphate + phosphatidylethanolamine[side 2]	-	?
ATP + H2O + phosphatidylserine[side 1]	-	Homo sapiens	ADP + phosphate + phosphatidylserine[side 2]	-	?

Synonyms

Synonyms	Comment	Organism
ATP11C	-	Homo sapiens
phospholipid flippase	-	Homo sapiens
PS-flippase	-	Homo sapiens

Expression

Organism	Comment	Expression
Homo sapiens	phospholipid flippase ATP11C is endocytosed and downregulated following Ca2+-mediated protein kinase C activation	down

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Release 2023.1 (January 2023)