EC Number |
Recommended Name |
Localization |
GeneOntology No. |
Reference |
---|
1.1.1.211 | long-chain-3-hydroxyacyl-CoA dehydrogenase |
mitochondrial membrane |
- |
GO:0031966 AmiGO QuickGO |
288673 |
1.1.1.300 | NADP-retinol dehydrogenase |
mitochondrial membrane |
- |
GO:0031966 AmiGO QuickGO |
740719 |
1.1.1.300 | NADP-retinol dehydrogenase |
mitochondrial membrane |
RDH13 is localized on the outer side of the inner mitochondrial membrane |
GO:0031966 AmiGO QuickGO |
686690 |
1.1.1.53 | 3alpha(or 20beta)-hydroxysteroid dehydrogenase |
mitochondrial membrane |
- |
GO:0031966 AmiGO QuickGO |
287111 |
1.1.5.13 | (S)-2-hydroxyglutarate dehydrogenase |
mitochondrial membrane |
- |
GO:0031966 AmiGO QuickGO |
752866, 755232 |
1.1.99.1 | choline dehydrogenase |
mitochondrial membrane |
- |
GO:0031966 AmiGO QuickGO |
711962, 741800 |
1.1.99.1 | choline dehydrogenase |
mitochondrial membrane |
CHDH appears to have a mitochondria-targeting sequence at its N-terminus (residues 1 to 38). CHDH is found on both the outer and inner membranes of mitochondria in resting cells. Upon induction of mitophagy, CHDH accumulates on the outer membrane in a mitochondrial potential-dependent manner. CHDH accumulates on the outer membrane following mitochondrial damage. Topology of CHDH in the mitochondrial membrane and mechanism by which CHDH translocates across the mitochondrial membranes, overview |
GO:0031966 AmiGO QuickGO |
741800 |
1.10.3.11 | ubiquinol oxidase (non-electrogenic) |
mitochondrial membrane |
- |
GO:0031966 AmiGO QuickGO |
-, 713637, 714291 |
1.10.3.11 | ubiquinol oxidase (non-electrogenic) |
mitochondrial membrane |
inner mitochondrial membrane |
GO:0031966 AmiGO QuickGO |
716586 |
1.10.3.11 | ubiquinol oxidase (non-electrogenic) |
mitochondrial membrane |
the alternative oxidase protein is expressed in the inner mitochondrial membrane in its reduced (active) form |
GO:0031966 AmiGO QuickGO |
715427 |
1.11.1.12 | phospholipid-hydroperoxide glutathione peroxidase |
mitochondrial membrane |
- |
GO:0031966 AmiGO QuickGO |
764701 |
1.11.1.9 | glutathione peroxidase |
mitochondrial membrane |
inner membrane |
GO:0031966 AmiGO QuickGO |
396636 |
1.11.1.9 | glutathione peroxidase |
mitochondrial membrane |
inner membrane: 95%, outer membrane: 2.5% |
GO:0031966 AmiGO QuickGO |
396629 |
1.14.13.9 | kynurenine 3-monooxygenase |
mitochondrial membrane |
- |
GO:0031966 AmiGO QuickGO |
-, 763915, 764296 |
1.14.13.9 | kynurenine 3-monooxygenase |
mitochondrial membrane |
the C terminus of the enzyme contains a putative outer mitochondrial membrane-targeting sequence and this portion of the molecule is required enzyme function |
GO:0031966 AmiGO QuickGO |
742349 |
1.14.15.15 | cholestanetriol 26-monooxygenase |
mitochondrial membrane |
- |
GO:0031966 AmiGO QuickGO |
439028, 439029 |
1.14.15.15 | cholestanetriol 26-monooxygenase |
mitochondrial membrane |
inner membrane-matrix |
GO:0031966 AmiGO QuickGO |
439024 |
1.14.15.15 | cholestanetriol 26-monooxygenase |
mitochondrial membrane |
membrane topology of CYP27A1, mapping of interacting peptides in the enzyme sequence, overview |
GO:0031966 AmiGO QuickGO |
705461 |
1.14.15.18 | calcidiol 1-monooxygenase |
mitochondrial membrane |
the CYP1alpha protein is located on the inner mitochondrial membrane |
GO:0031966 AmiGO QuickGO |
688676 |
1.14.15.5 | corticosterone 18-monooxygenase |
mitochondrial membrane |
- |
GO:0031966 AmiGO QuickGO |
438757, 438758 |
1.18.1.6 | adrenodoxin-NADP+ reductase |
mitochondrial membrane |
the enzyme associates with the inner mitochondrial membrane |
GO:0031966 AmiGO QuickGO |
719389 |
1.3.1.24 | biliverdin reductase |
mitochondrial membrane |
- |
GO:0031966 AmiGO QuickGO |
689373 |
1.3.2.3 | L-galactonolactone dehydrogenase |
mitochondrial membrane |
- |
GO:0031966 AmiGO QuickGO |
676600 |
1.3.5.1 | succinate dehydrogenase |
mitochondrial membrane |
- |
GO:0031966 AmiGO QuickGO |
687483, 687608, 687923, 724698 |
1.3.5.1 | succinate dehydrogenase |
mitochondrial membrane |
the enzyme has a heme b-containing membrane-anchoring dimer, comprising the Sdh3p and Sdh4p subunits, overview |
GO:0031966 AmiGO QuickGO |
685323 |
1.3.5.2 | dihydroorotate dehydrogenase (quinone) |
mitochondrial membrane |
- |
GO:0031966 AmiGO QuickGO |
712475 |
1.3.8.7 | medium-chain acyl-CoA dehydrogenase |
mitochondrial membrane |
- |
GO:0031966 AmiGO QuickGO |
674476 |
1.3.8.8 | long-chain acyl-CoA dehydrogenase |
mitochondrial membrane |
- |
GO:0031966 AmiGO QuickGO |
687810, 689007 |
1.3.8.9 | very-long-chain acyl-CoA dehydrogenase |
mitochondrial membrane |
- |
GO:0031966 AmiGO QuickGO |
739412 |
1.4.3.4 | monoamine oxidase |
mitochondrial membrane |
outer |
GO:0031966 AmiGO QuickGO |
706602 |
1.4.3.4 | monoamine oxidase |
mitochondrial membrane |
outer, membrane may have a role in controlling substrate binding, C-terminal transmembrane helix protrudes from each monomer and anchors the protein to the membrane, several apolar loops exposed on the protein surface are located in proximity of the C-terminal helix, providing additional membrane-binding interactions |
GO:0031966 AmiGO QuickGO |
655583 |
1.5.5.2 | proline dehydrogenase |
mitochondrial membrane |
a membrane-associated protein |
GO:0031966 AmiGO QuickGO |
-, 742162 |
1.5.5.2 | proline dehydrogenase |
mitochondrial membrane |
isozyme ProDH1 forms part of a low-molecular-mass (70-140 kDa) complex in the mitochondrial membrane, proteomic analysis |
GO:0031966 AmiGO QuickGO |
741858 |
1.5.99.B2 | proline dehydrogenase (acceptor) |
mitochondrial membrane |
inner mitochondrial membrane |
GO:0031966 AmiGO QuickGO |
726429 |
1.6.1.2 | NAD(P)+ transhydrogenase (Re/Si-specific) |
mitochondrial membrane |
- |
GO:0031966 AmiGO QuickGO |
392594, 392595, 392600, 392602, 392603, 392604, 392608, 392609, 392611, 392614, 392615, 392616, 392617, 392620, 392621, 392622, 392623, 392624, 392625, 392626, 392628, 392629, 392630, 392631, 392632, 392633, 392634, 392640, 392642, 392655, 392666, 659243, 695903, 734755, 735294 |
1.6.1.2 | NAD(P)+ transhydrogenase (Re/Si-specific) |
mitochondrial membrane |
membrane topography |
GO:0031966 AmiGO QuickGO |
392597 |
1.6.1.2 | NAD(P)+ transhydrogenase (Re/Si-specific) |
mitochondrial membrane |
membrane-associated |
GO:0031966 AmiGO QuickGO |
725679 |
1.6.1.2 | NAD(P)+ transhydrogenase (Re/Si-specific) |
mitochondrial membrane |
orientation in the inner mitochondrial membrane |
GO:0031966 AmiGO QuickGO |
392605 |
1.6.1.3 | NAD(P)+ transhydrogenase |
mitochondrial membrane |
- |
GO:0031966 AmiGO QuickGO |
741856 |
1.6.5.9 | NADH:quinone reductase (non-electrogenic) |
mitochondrial membrane |
- |
GO:0031966 AmiGO QuickGO |
714189, 714296 |
1.6.5.9 | NADH:quinone reductase (non-electrogenic) |
mitochondrial membrane |
mitochondrial inner membrane |
GO:0031966 AmiGO QuickGO |
392679 |
1.6.5.9 | NADH:quinone reductase (non-electrogenic) |
mitochondrial membrane |
NDH2 is oriented towards the external face of the mitochondrial inner membrane |
GO:0031966 AmiGO QuickGO |
-, 715708 |
1.6.5.9 | NADH:quinone reductase (non-electrogenic) |
mitochondrial membrane |
outer surface of the inner mitochondrial membrane |
GO:0031966 AmiGO QuickGO |
714305 |
1.8.5.4 | bacterial sulfide:quinone reductase |
mitochondrial membrane |
- |
GO:0031966 AmiGO QuickGO |
714950, 743229 |
1.8.5.8 | eukaryotic sulfide quinone oxidoreductase |
mitochondrial membrane |
- |
GO:0031966 AmiGO QuickGO |
743229, 744311 |
1.8.5.8 | eukaryotic sulfide quinone oxidoreductase |
mitochondrial membrane |
integral membrane protein, the two C-terminal helices lie in the plane of the mitochondrial membrane, with their hydrophobic faces communicating with the membrane interior. This monotopic mode of association allows the enzyme to gain access to its hydrophobic electron acceptor, CoQ |
GO:0031966 AmiGO QuickGO |
765845 |
2.1.1.100 | protein-S-isoprenylcysteine O-methyltransferase |
mitochondrial membrane |
- |
GO:0031966 AmiGO QuickGO |
485031 |
2.1.1.100 | protein-S-isoprenylcysteine O-methyltransferase |
mitochondrial membrane |
22% of the activity |
GO:0031966 AmiGO QuickGO |
485035 |
2.1.1.114 | polyprenyldihydroxybenzoate methyltransferase |
mitochondrial membrane |
- |
GO:0031966 AmiGO QuickGO |
733306 |
2.1.1.17 | phosphatidylethanolamine N-methyltransferase |
mitochondrial membrane |
- |
GO:0031966 AmiGO QuickGO |
698739 |
2.1.3.2 | aspartate carbamoyltransferase |
mitochondrial membrane |
- |
GO:0031966 AmiGO QuickGO |
485880 |
2.3.1.15 | glycerol-3-phosphate 1-O-acyltransferase |
mitochondrial membrane |
membrane-bound |
GO:0031966 AmiGO QuickGO |
486338, 486351 |
2.3.1.15 | glycerol-3-phosphate 1-O-acyltransferase |
mitochondrial membrane |
mtGPAT1 has two transmembrane domains (TMDs) (aa 472493 and aa 576592) with both the N- and C-termini facing the cytosol and a loop (aa 494575) facing the intermembrane space |
GO:0031966 AmiGO QuickGO |
671600 |
2.3.1.16 | acetyl-CoA C-acyltransferase |
mitochondrial membrane |
- |
GO:0031966 AmiGO QuickGO |
288673, 33713, 486411 |
2.3.1.21 | carnitine O-palmitoyltransferase |
mitochondrial membrane |
- |
GO:0031966 AmiGO QuickGO |
684893, 685368 |
2.3.1.24 | sphingosine N-acyltransferase |
mitochondrial membrane |
- |
GO:0031966 AmiGO QuickGO |
752899, 753223, 754575 |
2.3.1.297 | very-long-chain ceramide synthase |
mitochondrial membrane |
- |
GO:0031966 AmiGO QuickGO |
753223 |
2.5.1.141 | heme o synthase |
mitochondrial membrane |
inner |
GO:0031966 AmiGO QuickGO |
-, 727866 |
2.5.1.18 | glutathione transferase |
mitochondrial membrane |
bound |
GO:0031966 AmiGO QuickGO |
-, 721429 |
2.5.1.39 | 4-hydroxybenzoate polyprenyltransferase |
mitochondrial membrane |
- |
GO:0031966 AmiGO QuickGO |
723246 |
2.6.1.44 | alanine-glyoxylate transaminase |
mitochondrial membrane |
- |
GO:0031966 AmiGO QuickGO |
758712 |
2.7.1.1 | hexokinase |
mitochondrial membrane |
- |
GO:0031966 AmiGO QuickGO |
721945, 723383 |
2.7.1.91 | sphingosine kinase |
mitochondrial membrane |
- |
GO:0031966 AmiGO QuickGO |
-, 760839 |
2.7.11.13 | protein kinase C |
mitochondrial membrane |
- |
GO:0031966 AmiGO QuickGO |
704704 |
2.7.4.6 | nucleoside-diphosphate kinase |
mitochondrial membrane |
- |
GO:0031966 AmiGO QuickGO |
702391 |
2.7.7.4 | sulfate adenylyltransferase |
mitochondrial membrane |
enzyme form ATPSm is mainly associated with mitochondrial membrane |
GO:0031966 AmiGO QuickGO |
643278 |
2.7.7.41 | phosphatidate cytidylyltransferase |
mitochondrial membrane |
- |
GO:0031966 AmiGO QuickGO |
643309, 643310 |
2.7.7.41 | phosphatidate cytidylyltransferase |
mitochondrial membrane |
inner mitochondrial membrane |
GO:0031966 AmiGO QuickGO |
643302 |
2.7.8.11 | CDP-diacylglycerol-inositol 3-phosphatidyltransferase |
mitochondrial membrane |
- |
GO:0031966 AmiGO QuickGO |
645308 |
2.7.8.11 | CDP-diacylglycerol-inositol 3-phosphatidyltransferase |
mitochondrial membrane |
outer mitochondrial membrane |
GO:0031966 AmiGO QuickGO |
645318 |
2.7.8.29 | L-serine-phosphatidylethanolamine phosphatidyltransferase |
mitochondrial membrane |
- |
GO:0031966 AmiGO QuickGO |
722906, 741056 |
2.7.8.41 | cardiolipin synthase (CMP-forming) |
mitochondrial membrane |
- |
GO:0031966 AmiGO QuickGO |
-, 738289 |
2.8.2.B1 | APS sulfotransferase |
mitochondrial membrane |
in Euglena, sulfate activation and reduction are contained in a sulfate metabolizing centre on the outside of the mitochondrial inner membrane. This centre appears to supply the mitochondrion and the rest of the cell with the products of sulfate activation as well as with the reduced sulfur in form of cysteine |
GO:0031966 AmiGO QuickGO |
645745 |
3.1.1.29 | aminoacyl-tRNA hydrolase |
mitochondrial membrane |
- |
GO:0031966 AmiGO QuickGO |
730350 |
3.1.2.4 | 3-hydroxyisobutyryl-CoA hydrolase |
mitochondrial membrane |
- |
GO:0031966 AmiGO QuickGO |
665823 |
3.1.3.16 | protein-serine/threonine phosphatase |
mitochondrial membrane |
- |
GO:0031966 AmiGO QuickGO |
706505 |
3.1.3.27 | phosphatidylglycerophosphatase |
mitochondrial membrane |
- |
GO:0031966 AmiGO QuickGO |
94807, 94808, 94811 |
3.1.3.27 | phosphatidylglycerophosphatase |
mitochondrial membrane |
weak association to the mitochondrial membrane |
GO:0031966 AmiGO QuickGO |
94814 |
3.1.3.5 | 5'-nucleotidase |
mitochondrial membrane |
- |
GO:0031966 AmiGO QuickGO |
95050 |
3.1.3.51 | dolichyl-phosphatase |
mitochondrial membrane |
loosely bound to mitochondrial membranes |
GO:0031966 AmiGO QuickGO |
134919 |
3.1.4.37 | 2',3'-cyclic-nucleotide 3'-phosphodiesterase |
mitochondrial membrane |
- |
GO:0031966 AmiGO QuickGO |
729954 |
3.2.1.18 | exo-alpha-sialidase |
mitochondrial membrane |
- |
GO:0031966 AmiGO QuickGO |
681497 |
3.2.1.18 | exo-alpha-sialidase |
mitochondrial membrane |
outer mitochondrial membrane |
GO:0031966 AmiGO QuickGO |
729807 |
3.4.21.108 | HtrA2 peptidase |
mitochondrial membrane |
- |
GO:0031966 AmiGO QuickGO |
697178 |
3.4.24.64 | mitochondrial processing peptidase |
mitochondrial membrane |
beta subunit of MPP, not alpha subunit of MPP, Western blot of the mitochondrial subfractions |
GO:0031966 AmiGO QuickGO |
696812 |
3.4.24.B18 | m-AAA protease |
mitochondrial membrane |
- |
GO:0031966 AmiGO QuickGO |
733867 |
3.4.24.B18 | m-AAA protease |
mitochondrial membrane |
inner mitochondrial membrane |
GO:0031966 AmiGO QuickGO |
-, 734248 |
3.4.24.B18 | m-AAA protease |
mitochondrial membrane |
the catalytic domain is located in the mitochondrial matrix |
GO:0031966 AmiGO QuickGO |
733867 |
3.4.24.B18 | m-AAA protease |
mitochondrial membrane |
the m-AAA protease is a conserved hetero-oligomeric complex in the inner membrane of mitochondria. m-AAA protease is preferentially localized in the inner boundary membrane compared to the cristae membrane |
GO:0031966 AmiGO QuickGO |
694092 |
3.4.24.B19 | i-AAA protease |
mitochondrial membrane |
- |
GO:0031966 AmiGO QuickGO |
-, 733236, 734323, 734352 |
3.4.24.B19 | i-AAA protease |
mitochondrial membrane |
inner mitochondrial membrane |
GO:0031966 AmiGO QuickGO |
733731 |
3.4.24.B20 | FtsH protease |
mitochondrial membrane |
- |
GO:0031966 AmiGO QuickGO |
734984 |
3.4.99.B2 | D-aspartyl endopeptidase |
mitochondrial membrane |
- |
GO:0031966 AmiGO QuickGO |
719264 |
3.5.1.2 | glutaminase |
mitochondrial membrane |
one of the forms of phosphate activated glutaminase is associated with the inner mitochondrial membrane. Transport of glutamine into mitochondrial matrix may be a prerequisite for deamidation by phosphate activated glutaminase |
GO:0031966 AmiGO QuickGO |
689182 |
3.6.1.11 | exopolyphosphatase |
mitochondrial membrane |
- |
GO:0031966 AmiGO QuickGO |
696170, 719614 |
3.6.5.5 | dynamin GTPase |
mitochondrial membrane |
dynamin-related protein 1, DRP1 |
GO:0031966 AmiGO QuickGO |
720524 |
4.1.1.19 | arginine decarboxylase |
mitochondrial membrane |
most activity is associated with |
GO:0031966 AmiGO QuickGO |
656583 |
4.1.1.65 | phosphatidylserine decarboxylase |
mitochondrial membrane |
phosphatidylserine decarboxylase 1 |
GO:0031966 AmiGO QuickGO |
661240 |
4.1.2.27 | sphinganine-1-phosphate aldolase |
mitochondrial membrane |
- |
GO:0031966 AmiGO QuickGO |
713688 |
4.2.99.18 | DNA-(apurinic or apyrimidinic site) lyase |
mitochondrial membrane |
- |
GO:0031966 AmiGO QuickGO |
-, 648619 |