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Literature summary for 3.4.21.108 extracted from

  • Moisoi, N.; Klupsch, K.; Fedele, V.; East, P.; Sharma, S.; Renton, A.; Plun-Favreau, H.; Edwards, R.E.; Teismann, P.; Esposti, M.D.; Morrison, A.D.; Wood, N.W.; Downward, J.; Martins, L.M.
    Mitochondrial dysfunction triggered by loss of HtrA2 results in the activation of a brain-specific transcriptional stress response (2009), Cell Death Differ., 16, 449-464.
    View publication on PubMed
Search for more literature for 3.4.21.108

Application

Application Comment Organism
medicine loss of HtrA2 function might contribute to the activation of a stress response of mitochondrial origin in the brain that promotes neurodegeneration Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrial membrane
-
 Mus musculus 31966
-

Organism

Organism UniProt Comment Textmining
Mus musculus Q8BHC7
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Mus musculus
-
MEF cell
-
 Mus musculus
-
Neuro-2a cell
-
 Mus musculus
-
neuron
-
 Mus musculus
-

Synonyms

Synonyms Comment Organism
HtrA2 serine protease
-
 Mus musculus
Omi
-
 Mus musculus