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Information on EC 2.8.2.15 - steroid sulfotransferase
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EC Tree
2.8.2.15 steroid sulfotransferaseIUBMB Comments
Broad specificity resembling EC 2.8.2.2 alcohol sulfotransferase, but also acts on estrone.
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Word Map
- 2.8.2.15
-
sulfotransferases
- dheas
- hydroxysteroids
-
sults
- pregnenolone
-
sulfatase
- oxysterols
- 3beta-hydroxysteroids
- 3'-phosphoadenosine-5'-phosphosulfate
-
reticularis
- estrone
- 3-sulfate
-
sulfurylation
-
sulfoconjugation
- medicine
The enzyme appears in viruses and cellular organisms
Synonyms
sult2b1b, sult2b1, dhea-st, hsult2a1, cholesterol sulfotransferase, sult2a, steroid sulfotransferase, dhea sulfotransferase, st2b2, sulfotransferase ii, 
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SYNONYM 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
cholesterol sulfotransferase
cytosolic sulfotransferase
hydroxysteroid sulfotransferase
phenol sulfotransferase
steroid alcohol sulfotransferase
-
-
-
-
steroid/bile acid-sulfotransferase
sulfotransferase II
SULT2A1
SULT2B1
additional information
SULT2A1
-
-
additional information
-
SULT2A1 belongs to the family of phenol sulfotransferases
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REACTION
REACTION DIAGRAM
COMMENTARY
ORGANISM
UNIPROT
LITERATURE
3'-phosphoadenylyl sulfate + a phenolic steroid = adenosine 3',5'-bisphosphate + steroid O-sulfate
3'-phosphoadenylyl sulfate + a phenolic steroid = adenosine 3',5'-bisphosphate + steroid O-sulfate
broad specificity
-
-
-
3'-phosphoadenylyl sulfate + a phenolic steroid = adenosine 3',5'-bisphosphate + steroid O-sulfate
broad specificity resembling EC 2.8.2.2 alcohol sulfotransferase, but also acts on estrone
-
-
-
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
sulfate group transfer
-
-
-
-
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PATHWAY SOURCE
PATHWAYS
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SYSTEMATIC NAME
IUBMB Comments
3'-phosphoadenylyl-sulfate:phenolic-steroid sulfotransferase
Broad specificity resembling EC 2.8.2.2 alcohol sulfotransferase, but also acts on estrone.
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CAS REGISTRY NUMBER
COMMENTARY
9032-76-2
-
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SUBSTRATE
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
3'-phosphoadenylyl sulfate + 3,4-dihydroxyphenylacetic acid
adenosine 3',5'-bisphosphate + ?
3'-phosphoadenylyl sulfate + 3alpha-hydroxytibolone
adenosine 3',5'-bisphosphate + 3alpha-hydroxytibolone 3-O-sulfate
3'-phosphoadenylyl sulfate + 3beta-hydroxytibolone
adenosine 3',5'-bisphosphate + 3beta-hydroxytibolone 3-O-sulfate
3'-phosphoadenylyl sulfate + 4'-hydroxy-2,3',4,5'-tetrachlorobiphenyl
adenosine 3',5'-bisphosphate + 4'-hydroxy-2,3',4,5'-tetrachlorobiphenyl 4'-O-sulfate
-
i.e. 4'-OH PCB 68, substrate of SULT1A2
-
-
?
3'-phosphoadenylyl sulfate + 4-androstene-3,17-dione
adenosine 3',5'-bisphosphate + 3-O-sulfo-3,5-androstadien-3-ol-17-one
-
-
-
?
3'-phosphoadenylyl sulfate + 4-hydroxy-2',3,5-trichlorobiphenyl
adenosine 3',5'-bisphosphate + 2',3,5-trichlorobiphenyl-4-yl hydrogen sulfate
-
i.e. 4-OH PCB 34, substrate of SULT1A2
-
-
?
3'-phosphoadenylyl sulfate + 4-nitrophenol
adenosine 3',5'-bisphosphate + 4-nitrophenyl sulfate
3'-phosphoadenylyl sulfate + 5alpha,6alpha-epoxycholesterol
adenosine 3',5'-bisphosphate + 5alpha,6alpha-epoxycholesteryl sulfate
-
-
-
-
?
3'-phosphoadenylyl sulfate + 5beta,6beta-epoxycholesterol
adenosine 3',5'-bisphosphate + 5beta,6beta-epoxycholesteryl sulfate
-
-
-
-
?
3'-phosphoadenylyl sulfate + 6beta-hydroxytestosterone
adenosine 3',5'-bisphosphate + ?
-
-
-
?
3'-phosphoadenylyl sulfate + 7-oxo-cholesterol
adenosine 3',5'-bisphosphate + 7-oxo-cholesteryl sulfate
-
-
-
-
?
3'-phosphoadenylyl sulfate + 7alpha-hydroxycholesterol
adenosine 3',5'-bisphosphate + 7alpha-hydroxycholesteryl sulfate
-
-
-
-
?
3'-phosphoadenylyl sulfate + 7beta-hydroxycholesterol
adenosine 3',5'-bisphosphate + 7beta-hydroxycholesteryl sulfate
-
-
-
-
?
3'-phosphoadenylyl sulfate + aldosterone
adenosine 3',5'-bisphosphate + ?
-
-
-
?
3'-phosphoadenylyl sulfate + beta-estradiol
adenosine 3',5'-bisphosphate + beta-estradiol 3-sulfate
3'-phosphoadenylyl sulfate + cholesterol
adenosine 3',5'-bisphosphate + cholesterol sulfate
-
-
-
?
3'-phosphoadenylyl sulfate + cholesterol
adenosine 3',5'-bisphosphate + cholesteryl 3-sulfate
-
-
-
-
?
3'-phosphoadenylyl sulfate + cholesterol
adenosine 3',5'-bisphosphate + cholesteryl sulfate
-
-
-
-
?
3'-phosphoadenylyl sulfate + cortisol
adenosine 3',5'-bisphosphate + ?
-
-
-
?
3'-phosphoadenylyl sulfate + cortisone
adenosine 3',5'-bisphosphate + ?
-
-
-
?
3'-phosphoadenylyl sulfate + dehydroepiandrosterone
adenosine 3',5'-bisphosphate + dehydroepiandrosterone 3-O-sulfate
3'-phosphoadenylyl sulfate + dehydroepiandrosterone
adenosine 3',5'-bisphosphate + dehydroepiandrosterone 3-sulfate
-
-
-
-
?
3'-phosphoadenylyl sulfate + dehydroepiandrosterone
adenosine 3',5'-bisphosphate + dehydroepiandrosterone O-sulfate
-
-
-
-
?
3'-phosphoadenylyl sulfate + dehydroepiandrosterone
adenosine 3',5'-bisphosphate + dehydroepiandrosterone sulfate
3'-phosphoadenylyl sulfate + oxysterol
adenosine 3',5'-bisphosphate + oxysterol sulfate
-
-
-
?
3'-phosphoadenylyl sulfate + pregnenolone
adenosine 3',5'-bisphosphate + pregnenolone sulfate
3'-phosphoadenylyl sulfate + progesterone
adenosine 3',5'-bisphosphate + progesterone sulfate
-
-
-
?
3'-phosphoadenylyl sulfate + taurolithocholate
adenosine 3',5'-bisphosphate + taurolithocholate 3-sulfate
3'-phosphoadenylyl sulfate + testosterone
adenosine 3',5'-bisphosphate + ?
-
-
-
?
3'-phosphoadenylylsulfate + (22S,23S)-28-homobrassinolide
adenosine 3',5'-bisphosphate + (22S,23S)-28-homobrassinolide sulfate
-
-
-
-
r
3'-phosphoadenylylsulfate + (22S,23S)-28-homocastasterone
adenosine 3',5'-bisphosphate + (22S,23S)-28-homocastasterone sulfate
-
-
-
-
r
3'-phosphoadenylylsulfate + 11-deoxycorticosterone
adenosine 3',5'-bisphosphate + 11-deoxycorticosterone sulfate
-
21-hydroxypregn-4-en-3,20-dione
pregn-4-en-3-one 21-sulfate
r
3'-phosphoadenylylsulfate + 16-hydroxy-estradiol
adenosine 3',5'-bisphosphate + ?
-
-
-
-
r
3'-phosphoadenylylsulfate + 17alpha-ethynylestradiol
adenosine 3',5'-bisphosphate + 17alpha-ethynylestradiol 3-sulfate
-
celecoxib switches sulfation from the 3-O-position to the 17beta-O-position
-
-
?
3'-phosphoadenylylsulfate + 17beta-estradiol
adenosine 3',5'-bisphosphate + estradiol-17beta 3-sulfate
3'-phosphoadenylylsulfate + 17beta-estradiol 3-methyl ether
adenosine 3',5'-bisphosphate + ?
-
-
-
-
r
3'-phosphoadenylylsulfate + 2-hydroxy-estradiol
adenosine 3',5'-bisphosphate + ?
-
-
-
-
r
3'-phosphoadenylylsulfate + 24-epibrassinolide
adenosine 3',5'-bisphosphate + 24-epibrassinolide sulfate
-
sulfonation leads to the loss of biological activity
-
-
r
3'-phosphoadenylylsulfate + 24-epicastasterone
adenosine 3',5'-bisphosphate + 24-epicastasterone 3-sulfate
3'-phosphoadenylylsulfate + 24-epicastasterone
adenosine 3',5'-bisphosphate + 24-epicastasterone sulfate
3'-phosphoadenylylsulfate + 24-epiteasterone
adenosine 3',5'-bisphosphate + 24-epiteasterone 3-sulfate
-
-
-
?
3'-phosphoadenylylsulfate + 24-epiteasterone
adenosine 3',5'-bisphosphate + 24-epiteasterone sulfate
-
-
-
-
r
3'-phosphoadenylylsulfate + 3,3',5-triidothyronine
adenosine 3',5'-bisphosphate + 3,3',5-triiodothyronine 4'-sulfate
-
-
-
?
3'-phosphoadenylylsulfate + 3alpha-hydroxy-5alpha-androstan-17-one
adenosine 3',5'-bisphosphate + 5alpha-androstan-17-one 3-sulfate
3'-phosphoadenylylsulfate + 3beta-hydroxy-5alpha-androstan-17-one
adenosine 3',5'-bisphosphate + 5alpha-androstan-17-one 3-sulfate
3'-phosphoadenylylsulfate + 4'-hydroxy-2',3,4-trichlorobiphenyl
adenosine 3',5'-bisphosphate + ?
-
-
-
-
?
3'-phosphoadenylylsulfate + 4'-hydroxy-2,3',4-trichlorobiphenyl
adenosine 3',5'-bisphosphate + ?
-
-
-
-
?
3'-phosphoadenylylsulfate + 4-hydroxy-2',3,5-trichlorobiphenyl
adenosine 3',5'-bisphosphate + ?
-
-
-
-
?
3'-phosphoadenylylsulfate + 4-hydroxy-2,4'-dichlorobiphenyl
adenosine 3',5'-bisphosphate + ?
-
-
-
-
?
3'-phosphoadenylylsulfate + 4-hydroxy-3,3',5-trichlorobiphenyl
adenosine 3',5'-bisphosphate + ?
-
-
-
-
?
3'-phosphoadenylylsulfate + 4-hydroxy-3,3'-dichlorobiphenyl
adenosine 3',5'-bisphosphate + ?
-
-
-
-
?
3'-phosphoadenylylsulfate + 4-hydroxy-3,5-dichlorobiphenyl
adenosine 3',5'-bisphosphate + ?
-
-
-
-
?
3'-phosphoadenylylsulfate + 4-hydroxy-estradiol
adenosine 3',5'-bisphosphate + ?
-
-
-
-
r
3'-phosphoadenylylsulfate + 4-nitrophenol
adenosine 3',5'-bisphosphate + 4-nitrophenyl sulfate
-
-
-
?
3'-phosphoadenylylsulfate + 5alpha-androst-16-en-3beta-ol
adenosine 3',5'-bisphosphate + ?
-
-
-
-
r
3'-phosphoadenylylsulfate + 6-deoxo-24-epicastasterone
adenosine 3',5'-bisphosphate + 6-deoxo-24-epicastasterone sulfate
-
-
-
-
r
3'-phosphoadenylylsulfate + allopregnanolone
adenosine 3',5'-bisphosphate + allopregnanolone sulfate
-
-
-
-
?
3'-phosphoadenylylsulfate + allopregnenolone
adenosine 3',5'-bisphosphate + allopregnenolone sulfate
3'-phosphoadenylylsulfate + androst-5-ene-3beta,17beta-diol
adenosine 3',5'-bisphosphate + ?
-
-
-
-
r
3'-phosphoadenylylsulfate + androst-5-ene-3beta17alpha-diol
adenosine 3',5'-bisphosphate + ?
-
-
-
-
r
3'-phosphoadenylylsulfate + androstenediol
adenosine 3',5'-bisphosphate + 17beta-hydroxy-androst-5-en-3-sulfate
-
-
-
?
3'-phosphoadenylylsulfate + androstenediol
adenosine 3',5'-bisphosphate + ?
SULT2B1 isoform
-
-
r
3'-phosphoadenylylsulfate + androsterone
adenosine 3',5'-bisphosphate + 5alpha-androstane-17-one 3-sulfate
3'-phosphoadenylylsulfate + beta-naphthol
adenosine 3',5'-bisphosphate + 2-naphthyl sulfate
-
-
-
?
3'-phosphoadenylylsulfate + butylated hydroxy anisole
adenosine 3',5'-bisphosphate + ?
-
-
-
?
3'-phosphoadenylylsulfate + caffeic acid
adenosine 3',5'-bisphosphate + ?
-
-
-
?
3'-phosphoadenylylsulfate + catechin
adenosine 3',5'-bisphosphate + ?
-
-
-
?
3'-phosphoadenylylsulfate + chlorogenic acid
adenosine 3',5'-bisphosphate + ?
-
-
-
?
3'-phosphoadenylylsulfate + cholesterol
adenosine 3',5'-bisphosphate + cholesterol 3-sulfate
3'-phosphoadenylylsulfate + cholesterol
adenosine 3',5'-bisphosphate + cholesterol sulfate
-
sulfurylated at low rate
-
-
r
3'-phosphoadenylylsulfate + cortisol
adenosine 3',5'-bisphosphate + cortisol sulfate
-
-
-
-
r
3'-phosphoadenylylsulfate + daidzein
adenosine 3',5'-bisphosphate + ?
-
-
-
?
3'-phosphoadenylylsulfate + dehydroepiandrosterone
adenosine 3',5'-bisphosphate + ?
-
-
-
?
3'-phosphoadenylylsulfate + dehydroepiandrosterone
adenosine 3',5'-bisphosphate + androst-5-en-17-one 3-sulfate
3'-phosphoadenylylsulfate + dehydroepiandrosterone
adenosine 3',5'-bisphosphate + dehydroepiandrosterone 3-sulfate
3'-phosphoadenylylsulfate + diethylstilbestrol
adenosine 3',5'-bisphosphate + diethylstilbestrol sulfate
-
synthetic estrogen
-
r
3'-phosphoadenylylsulfate + epigallocatechin gallate
adenosine 3',5'-bisphosphate + ?
-
-
-
?
3'-phosphoadenylylsulfate + epitestosterone
adenosine 3',5'-bisphosphate + epitestosterone sulfate
-
17alpha-hydroxyandrost-4-en-3-one
androst-4-en-3-one 17-sulfate
r
3'-phosphoadenylylsulfate + estradiol
adenosine 3',5'-bisphosphate + ?
-
-
-
-
?
3'-phosphoadenylylsulfate + etiocholanone
adenosine 3',5'-bisphosphate + etiocholanone sulfate
3'-phosphoadenylylsulfate + kaempferol
adenosine 3',5'-bisphosphate + ?
-
-
-
?
3'-phosphoadenylylsulfate + myricetin
adenosine 3',5'-bisphosphate + ?
-
-
-
?
3'-phosphoadenylylsulfate + n-propyl gallate
adenosine 3',5'-bisphosphate + ?
-
-
-
?
3'-phosphoadenylylsulfate + pregnenolone
adenosine 3',5'-bisphosphate + pregn-5-en-20-one 3-sulfate
-
-
-
?
3'-phosphoadenylylsulfate + pregnenolone
adenosine 3',5'-bisphosphate + pregnenolone 3-sulfate
-
-
-
-
?
3'-phosphoadenylylsulfate + pregnenolone
adenosine 3',5'-bisphosphate + pregnenolone sulfate
3'-phosphoadenylylsulfate + quercetin
adenosine 3',5'-bisphosphate + ?
-
-
-
?
3'-phosphoadenylylsulfate + testosterone
adenosine 3',5'-bisphosphate + testosterone sulfate
3'-phosphoadenylylsulfate + thyroxine
adenosyl 3',5'-bisphosphate + O-[3,5-diiodo-4-(sulfooxy)phenyl]-3,5-diiodotyrosine
-
-
-
?
3'-phosphoadenylyl sulfate + 1-naphthol
adenosine 3',5'-bisphosphate + 1-naphthyl sulfate
-
-
-
-
?
3'-phosphoadenylyl sulfate + 1-naphthol
adenosine 3',5'-bisphosphate + 1-naphthyl sulfate
-
-
-
-
?
3'-phosphoadenylyl sulfate + 3,4-dihydroxyphenylacetic acid
adenosine 3',5'-bisphosphate + ?
-
-
-
-
?
3'-phosphoadenylyl sulfate + 3,4-dihydroxyphenylacetic acid
adenosine 3',5'-bisphosphate + ?
-
-
-
-
?
3'-phosphoadenylyl sulfate + 3alpha-hydroxytibolone
adenosine 3',5'-bisphosphate + 3alpha-hydroxytibolone 3-O-sulfate
-
-
-
-
?
3'-phosphoadenylyl sulfate + 3alpha-hydroxytibolone
adenosine 3',5'-bisphosphate + 3alpha-hydroxytibolone 3-O-sulfate
-
sulfation inactivates the hydroxylated metabolite of tibolone, a synthetic steroid used for the treatment for climacteric symptoms and postmenopausal osteoporosis
-
-
?
3'-phosphoadenylyl sulfate + 3beta-hydroxytibolone
adenosine 3',5'-bisphosphate + 3beta-hydroxytibolone 3-O-sulfate
-
-
-
-
?
3'-phosphoadenylyl sulfate + 3beta-hydroxytibolone
adenosine 3',5'-bisphosphate + 3beta-hydroxytibolone 3-O-sulfate
-
sulfation inactivates the hydroxylated metabolite of tibolone, a synthetic steroid used for the treatment for climacteric symptoms and postmenopausal osteoporosis
-
-
?
3'-phosphoadenylyl sulfate + 4-nitrophenol
adenosine 3',5'-bisphosphate + 4-nitrophenyl sulfate
-
-
-
-
?
3'-phosphoadenylyl sulfate + 4-nitrophenol
adenosine 3',5'-bisphosphate + 4-nitrophenyl sulfate
-
-
-
-
?
3'-phosphoadenylyl sulfate + beta-estradiol
adenosine 3',5'-bisphosphate + beta-estradiol 3-sulfate
-
-
-
-
?
3'-phosphoadenylyl sulfate + beta-estradiol
adenosine 3',5'-bisphosphate + beta-estradiol 3-sulfate
-
-
-
-
?
3'-phosphoadenylyl sulfate + dehydroepiandrosterone
adenosine 3',5'-bisphosphate + ?
-
-
-
-
?
3'-phosphoadenylyl sulfate + dehydroepiandrosterone
adenosine 3',5'-bisphosphate + ?
-
-
-
-
?
3'-phosphoadenylyl sulfate + dehydroepiandrosterone
adenosine 3',5'-bisphosphate + dehydroepiandrosterone 3-O-sulfate
-
-
-
-
?
3'-phosphoadenylyl sulfate + dehydroepiandrosterone
adenosine 3',5'-bisphosphate + dehydroepiandrosterone 3-O-sulfate
-
-
-
?
3'-phosphoadenylyl sulfate + dehydroepiandrosterone
adenosine 3',5'-bisphosphate + dehydroepiandrosterone 3-O-sulfate
preferred substrate
-
-
?
3'-phosphoadenylyl sulfate + dehydroepiandrosterone
adenosine 3',5'-bisphosphate + dehydroepiandrosterone 3-O-sulfate
-
variant haplotypes in tissues possessing alterations in activity or stability may alter the plasma levels of dehydroepiandrosterone and dehydroepiandrosterone sulfate thereby altering the conversion of dehydroepiandrosterone in tissues, overview
-
-
?
3'-phosphoadenylyl sulfate + dehydroepiandrosterone
adenosine 3',5'-bisphosphate + dehydroepiandrosterone 3-O-sulfate
-
i.e. DHEA, substrate of SULT1A2
-
-
?
3'-phosphoadenylyl sulfate + dehydroepiandrosterone
adenosine 3',5'-bisphosphate + dehydroepiandrosterone 3-O-sulfate
-
-
-
-
?
3'-phosphoadenylyl sulfate + dehydroepiandrosterone
adenosine 3',5'-bisphosphate + dehydroepiandrosterone 3-O-sulfate
-
-
-
?
3'-phosphoadenylyl sulfate + dehydroepiandrosterone
adenosine 3',5'-bisphosphate + dehydroepiandrosterone sulfate
-
-
-
?
3'-phosphoadenylyl sulfate + dehydroepiandrosterone
adenosine 3',5'-bisphosphate + dehydroepiandrosterone sulfate
-
-
-
?
3'-phosphoadenylyl sulfate + desipramine
adenosine 3',5'-bisphosphate + ?
-
-
-
-
?
3'-phosphoadenylyl sulfate + desipramine
adenosine 3',5'-bisphosphate + ?
-
-
-
-
?
3'-phosphoadenylyl sulfate + L-triiodothyronine
adenosine 3',5'-bisphosphate + ?
-
-
-
?
3'-phosphoadenylyl sulfate + L-triiodothyronine
adenosine 3',5'-bisphosphate + ?
-
-
-
-
?
3'-phosphoadenylyl sulfate + L-triiodothyronine
adenosine 3',5'-bisphosphate + ?
-
-
-
-
?
3'-phosphoadenylyl sulfate + pregnenolone
adenosine 3',5'-bisphosphate + pregnenolone sulfate
-
-
-
?
3'-phosphoadenylyl sulfate + pregnenolone
adenosine 3',5'-bisphosphate + pregnenolone sulfate
-
-
-
?
3'-phosphoadenylyl sulfate + taurolithocholate
adenosine 3',5'-bisphosphate + taurolithocholate 3-sulfate
-
-
-
-
r
3'-phosphoadenylyl sulfate + taurolithocholate
adenosine 3',5'-bisphosphate + taurolithocholate 3-sulfate
-
-
-
-
r
3'-phosphoadenylyl sulfate + xanthurenic acid
adenosine 3',5'-bisphosphate + ?
-
-
-
-
?
3'-phosphoadenylyl sulfate + xanthurenic acid
adenosine 3',5'-bisphosphate + ?
-
-
-
-
?
3'-phosphoadenylylsulfate + 17alpha-estradiol
adenosine 3',5'-bisphosphate + ?
-
estra-1,3,5(10)-triene-3,17alpha-diol
-
-
r
3'-phosphoadenylylsulfate + 17alpha-estradiol
adenosine 3',5'-bisphosphate + ?
-
estra-1,3,5(10)-triene-3,17alpha-diol
-
-
r
3'-phosphoadenylylsulfate + 17alpha-estradiol
adenosine 3',5'-bisphosphate + ?
-
estra-1,3,5(10)-triene-3,17alpha-diol
-
-
r
3'-phosphoadenylylsulfate + 17beta-estradiol
adenosine 3',5'-bisphosphate + ?
-
-
-
-
r
3'-phosphoadenylylsulfate + 17beta-estradiol
adenosine 3',5'-bisphosphate + ?
-
-
-
-
r
3'-phosphoadenylylsulfate + 17beta-estradiol
adenosine 3',5'-bisphosphate + ?
-
3alphaHST isoform
-
-
r
3'-phosphoadenylylsulfate + 17beta-estradiol
adenosine 3',5'-bisphosphate + ?
-
chorion enzyme catalyzes sulfation of estradiol at about double the velocity of estrone
-
-
r
3'-phosphoadenylylsulfate + 17beta-estradiol
adenosine 3',5'-bisphosphate + ?
-
-
-
-
r
3'-phosphoadenylylsulfate + 17beta-estradiol
adenosine 3',5'-bisphosphate + ?
-
estra-1,3,5(10)-triene-3,17alpha-diol
-
-
r
3'-phosphoadenylylsulfate + 17beta-estradiol
adenosine 3',5'-bisphosphate + ?
-
-
-
-
r
3'-phosphoadenylylsulfate + 17beta-estradiol
adenosine 3',5'-bisphosphate + ?
-
-
-
-
r
3'-phosphoadenylylsulfate + 17beta-estradiol
adenosine 3',5'-bisphosphate + ?
-
estra-1,3,5(10)-triene-3,17alpha-diol
-
-
r
3'-phosphoadenylylsulfate + 17beta-estradiol
adenosine 3',5'-bisphosphate + ?
-
estra-1,3,5(10)-triene-3,17alpha-diol
-
-
r
3'-phosphoadenylylsulfate + 17beta-estradiol
adenosine 3',5'-bisphosphate + estradiol-17beta 3-sulfate
-
-
-
?
3'-phosphoadenylylsulfate + 17beta-estradiol
adenosine 3',5'-bisphosphate + estradiol-17beta 3-sulfate
-
-
-
?
3'-phosphoadenylylsulfate + 2-naphthol
adenosine 3',5'-bisphosphate + 2-naphthyl sulfate
-
-
-
-
r
3'-phosphoadenylylsulfate + 2-naphthol
adenosine 3',5'-bisphosphate + 2-naphthyl sulfate
-
-
-
-
r
3'-phosphoadenylylsulfate + 24-epicastasterone
adenosine 3',5'-bisphosphate + 24-epicastasterone 3-sulfate
-
-
-
-
?
3'-phosphoadenylylsulfate + 24-epicastasterone
adenosine 3',5'-bisphosphate + 24-epicastasterone 3-sulfate
-
-
-
?
3'-phosphoadenylylsulfate + 24-epicastasterone
adenosine 3',5'-bisphosphate + 24-epicastasterone sulfate
-
-
-
-
r
3'-phosphoadenylylsulfate + 24-epicastasterone
adenosine 3',5'-bisphosphate + 24-epicastasterone sulfate
-
highest affinity
-
-
r
3'-phosphoadenylylsulfate + 3alpha-hydroxy-5alpha-androstan-17-one
adenosine 3',5'-bisphosphate + 5alpha-androstan-17-one 3-sulfate
-
-
-
r
3'-phosphoadenylylsulfate + 3alpha-hydroxy-5alpha-androstan-17-one
adenosine 3',5'-bisphosphate + 5alpha-androstan-17-one 3-sulfate
-
3alphaHST isoform
-
r
3'-phosphoadenylylsulfate + 3alpha-hydroxy-5alpha-androstan-17-one
adenosine 3',5'-bisphosphate + 5alpha-androstan-17-one 3-sulfate
-
-
-
r
3'-phosphoadenylylsulfate + 3alpha-hydroxy-5alpha-androstan-17-one
adenosine 3',5'-bisphosphate + 5alpha-androstan-17-one 3-sulfate
-
androsterone
androsterone sulfate
r
3'-phosphoadenylylsulfate + 3alpha-hydroxy-5alpha-androstan-17-one
adenosine 3',5'-bisphosphate + 5alpha-androstan-17-one 3-sulfate
-
androsterone
androsterone sulfate
r
3'-phosphoadenylylsulfate + 3alpha-hydroxy-5alpha-androstan-17-one
adenosine 3',5'-bisphosphate + 5alpha-androstan-17-one 3-sulfate
-
androsterone
androsterone sulfate
r
3'-phosphoadenylylsulfate + 3beta-hydroxy-5alpha-androstan-17-one
adenosine 3',5'-bisphosphate + 5alpha-androstan-17-one 3-sulfate
SULT2B1 isoform
-
r
3'-phosphoadenylylsulfate + 3beta-hydroxy-5alpha-androstan-17-one
adenosine 3',5'-bisphosphate + 5alpha-androstan-17-one 3-sulfate
-
epiandrosterone
-
r
3'-phosphoadenylylsulfate + 3beta-hydroxy-5alpha-androstan-17-one
adenosine 3',5'-bisphosphate + 5alpha-androstan-17-one 3-sulfate
-
epiandrosterone
-
r
3'-phosphoadenylylsulfate + 3beta-hydroxy-5alpha-androstan-17-one
adenosine 3',5'-bisphosphate + 5alpha-androstan-17-one 3-sulfate
-
epiandrosterone
-
r
3'-phosphoadenylylsulfate + allopregnenolone
adenosine 3',5'-bisphosphate + allopregnenolone sulfate
-
-
-
-
?
3'-phosphoadenylylsulfate + allopregnenolone
adenosine 3',5'-bisphosphate + allopregnenolone sulfate
-
3alphaHST isoform
-
r
3'-phosphoadenylylsulfate + androsterone
adenosine 3',5'-bisphosphate + 5alpha-androstane-17-one 3-sulfate
-
-
-
-
?
3'-phosphoadenylylsulfate + androsterone
adenosine 3',5'-bisphosphate + 5alpha-androstane-17-one 3-sulfate
-
enzyme is an androsterone sulfotransferase as well as a dehydroepiandrosterone sulfotransferase, implying an important role in steroid homeostasis for the adrenals and liver
-
-
?
3'-phosphoadenylylsulfate + cholesterol
adenosine 3',5'-bisphosphate + cholesterol 3-sulfate
-
-
-
-
?
3'-phosphoadenylylsulfate + cholesterol
adenosine 3',5'-bisphosphate + cholesterol 3-sulfate
-
SULT2B1b, concentration-dependent induction by Ca2+
-
-
?
3'-phosphoadenylylsulfate + cholesterol
adenosine 3',5'-bisphosphate + cholesterol 3-sulfate
-
SULT2B1b
-
-
?
3'-phosphoadenylylsulfate + cholesterol
adenosine 3',5'-bisphosphate + cholesterol 3-sulfate
-
-
-
-
?
3'-phosphoadenylylsulfate + dehydroepiandrosterone
adenosine 3',5'-bisphosphate + androst-5-en-17-one 3-sulfate
-
-
-
-
?
3'-phosphoadenylylsulfate + dehydroepiandrosterone
adenosine 3',5'-bisphosphate + androst-5-en-17-one 3-sulfate
-
enzyme is an androsterone sulfotransferase as well as a dehydroepiandrosterone sulfotransferase, implying an important role in steroid homeostasis for the adrenals and liver
-
-
?
3'-phosphoadenylylsulfate + dehydroepiandrosterone
adenosine 3',5'-bisphosphate + dehydroepiandrosterone 3-sulfate
-
-
-
-
r
3'-phosphoadenylylsulfate + dehydroepiandrosterone
adenosine 3',5'-bisphosphate + dehydroepiandrosterone 3-sulfate
-
3betaHST isoform
-
-
r