Cloned (Comment) | Organism |
---|---|
expression and expression analysis of wild-type and mutant SULT2A1 | Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
A679G | naturally occuring polymorphisms of SULT2A1, genotyping, SULT2A1 variant allele frequencies in African-American populations, overview | Homo sapiens |
G187C | naturally occuring polymorphisms of SULT2A1, genotyping, SULT2A1 variant allele frequencies in African-American populations, overview | Homo sapiens |
G781A | naturally occuring polymorphisms of SULT2A1, genotyping, SULT2A1 variant allele frequencies in African-American populations, overview | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
3'-phosphoadenylyl sulfate + dehydroepiandrosterone | Homo sapiens | variant haplotypes in tissues possessing alterations in activity or stability may alter the plasma levels of dehydroepiandrosterone and dehydroepiandrosterone sulfate thereby altering the conversion of dehydroepiandrosterone in tissues, overview | adenosine 3',5'-bisphosphate + dehydroepiandrosterone 3-O-sulfate | - |
? | |
additional information | Homo sapiens | SULT2A1 plays a very important role in formation of steroid sulfate esters, and sulfates both 3alpha- and 3beta-hydroxysteroids, estrogens, testosterone, and aliphatic hydroxyl-containing drugs and xenobiotics | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
SULT2A1 | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
adrenal gland | fetal, and adult adrenal reticular layer as well as adrenal cortex, SULT2A1 | Homo sapiens | - |
liver | SULT2A1 | Homo sapiens | - |
additional information | variant haplotypes in tissues possessing alterations in activity or stability may alter the plasma levels of dehydroepiandrosterone and dehydroepiandrosterone sulfate thereby altering the conversion of dehydroepiandrosterone in tissues, overview | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
3'-phosphoadenylyl sulfate + dehydroepiandrosterone | - |
Homo sapiens | adenosine 3',5'-bisphosphate + dehydroepiandrosterone 3-O-sulfate | - |
? | |
3'-phosphoadenylyl sulfate + dehydroepiandrosterone | variant haplotypes in tissues possessing alterations in activity or stability may alter the plasma levels of dehydroepiandrosterone and dehydroepiandrosterone sulfate thereby altering the conversion of dehydroepiandrosterone in tissues, overview | Homo sapiens | adenosine 3',5'-bisphosphate + dehydroepiandrosterone 3-O-sulfate | - |
? | |
additional information | SULT2A1 plays a very important role in formation of steroid sulfate esters, and sulfates both 3alpha- and 3beta-hydroxysteroids, estrogens, testosterone, and aliphatic hydroxyl-containing drugs and xenobiotics | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
dehydroepiandrosterone sulfotransferase | - |
Homo sapiens |
SULT2A1 | - |
Homo sapiens |