Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.8.2.15 extracted from

  • Ou, Z.; Shi, X.; Gilroy, R.K.; Kirisci, L.; Romkes, M.; Lynch, C.; Wang, H.; Xu, M.; Jiang, M.; Ren, S.; Gramignoli, R.; Strom, S.C.; Huang, M.; Xie, W.
    Regulation of the human hydroxysteroid sulfotransferase (SULT2A1) by RORalpha and RORgamma and its potential relevance to human liver diseases (2013), Mol. Endocrinol., 27, 106-115.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.8.2.15

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3'-phosphoadenylylsulfate + dehydroepiandrosterone Homo sapiens
-
 adenosine 3',5'-bisphosphate + dehydroepiandrosterone 3-sulfate
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
Hep-G2 cell
-
 Homo sapiens
-
hepatocyte
-
 Homo sapiens
-
liver
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3'-phosphoadenylylsulfate + dehydroepiandrosterone
-
 Homo sapiens adenosine 3',5'-bisphosphate + dehydroepiandrosterone 3-sulfate
-
 ?

Synonyms

Synonyms Comment Organism
hydroxysteroid sulfotransferase
-
 Homo sapiens
SULT2A1
-
 Homo sapiens

Expression

Organism Comment Expression
Homo sapiens down-regulation of RORalpha and/or RORgamma by small interfering RNA inhibits the expression of endogenous SULT2A1 down
Homo sapiens retinoid-related orphan receptor (ROR)alpha and RORgamma transactivate the SULT2A1 gene promoter through their binding to a ROR response element found in the SULT2A1 gene promoter up