Protein Variants | Comment | Organism |
---|---|---|
additional information | farnesoid X receptor FXR-null mice express a constitutively high level of SULT2A | Mus musculus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
dehydroepiandrosterone | substrate inhibition | Mus musculus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Mus musculus | 5829 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
3'-phosphoadenylyl sulfate + dehydroepiandrosterone | Mus musculus | - |
adenosine 3',5'-bisphosphate + dehydroepiandrosterone 3-sulfate | - |
? | |
additional information | Mus musculus | Sult2a is involved in 3alpha-sulfation of bile acids, e.g. of litocholic acid, required for enhanced faecal excretion of bile acid in hydroxysteroid sulfotransferase-mediated protection against lithocholic acid-induced liver toxicity, overview | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
wild-type C57BL/6N mice and farnesoid X receptor FXR-null mice | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Mus musculus | - |
additional information | farnesoid X receptor FXR-null mice express a constitutively high level of SULT2A | Mus musculus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
determination of 3alpha-sulfated bile acids | Mus musculus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
3'-phosphoadenylyl sulfate + dehydroepiandrosterone | - |
Mus musculus | adenosine 3',5'-bisphosphate + dehydroepiandrosterone 3-sulfate | - |
? | |
additional information | Sult2a is involved in 3alpha-sulfation of bile acids, e.g. of litocholic acid, required for enhanced faecal excretion of bile acid in hydroxysteroid sulfotransferase-mediated protection against lithocholic acid-induced liver toxicity, overview | Mus musculus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
hydroxysteroid sulfotransferase | - |
Mus musculus |
More | cf. EC 2.8.2.2 | Mus musculus |
Sult2a | - |
Mus musculus |