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Literature summary for 2.8.2.15 extracted from

  • Shimada, M.; Matsuda, T.; Sato, A.; Akase, T.; Matsubara, T.; Nagata, K.; Yamazoe, Y.
    Expression of a skin cholesterol sulfotransferase, St2b2, is a trigger of epidermal cell differentiation (2008), Xenobiotica, 38, 1487-1499.
    View publication on PubMed
Search for more literature for 2.8.2.15

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli strain M15 Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Mus musculus 5829
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3'-phosphoadenylyl sulfate + cholesterol Mus musculus
-
 adenosine 3',5'-bisphosphate + cholesteryl 3-sulfate
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
Ni-NTA column chromatography Mus musculus

Source Tissue

Source Tissue Comment Organism Textmining
epidermal cell
-
 Mus musculus
-
primary cell
-
 Mus musculus
-
skin in the basement layer of normal skin Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3'-phosphoadenylyl sulfate + cholesterol
-
 Mus musculus adenosine 3',5'-bisphosphate + cholesteryl 3-sulfate
-
 ?

Synonyms

Synonyms Comment Organism
cholesterol sulfotransferase
-
 Mus musculus
St2b2
-
 Mus musculus

Expression

Organism Comment Expression
Mus musculus highest expression level is detected in epidermis from 3-day-old mice and then decreases before maturation up

General Information

General Information Comment Organism
physiological function expression of St2b2 is a trigger of epidermal cell differentiation by controlling cholesterol sulfate level in the cells Mus musculus