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Information on EC - geraniol 8-hydroxylase

for references in articles please use BRENDA:EC1.14.14.83
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IUBMB Comments
A cytochrome P-450 (heme thiolate) protein found in plants. Also hydroxylates nerol and citronellol, cf. EC, linalool 8-monooxygenase. The recommended numbering of geraniol gives 8-hydroxygeraniol as the product rather than 10-hydroxygeraniol as used by references 1-3. See prenol nomenclature {iupac/misc/prenol#p1::Pr-1}. The cloned enzyme also catalysed, but less efficiently, the 3'-hydroxylation of naringenin (cf. EC, flavonoid 3'-monooxygenase) .
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The expected taxonomic range for this enzyme is: Eukaryota, Bacteria
10-hydroxygeraniol oxidoreductase, CPR I, Cr10HGO, CYP76B10, CYP76B6, CYP76B6 protein, CYP76F45, G10H, G8H, geraniol 10-hydroxylase, more
geraniol + [reduced NADPH-hemoprotein reductase] + O2 = (6E)-8-hydroxygeraniol + [oxidized NADPH-hemoprotein reductase] + H2O
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