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BRENDA support

Ligand geraniol

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Basic Ligand Information

Molecular Structure
Picture of geraniol (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C10H18O
geraniol
GLZPCOQZEFWAFX-JXMROGBWSA-N
Synonyms:
(2E)-3,7-dimethylocta-2,6-dien-1-ol, (2E)-geraniol, (E)-geraniol, citryl alcohol, geranyl alcohol


Show all pahtways known for Show all BRENDA pathways known for geraniol

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (11 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
geraniol + NAD+ = geranial + NADH + H+
show the reaction diagram
-
geraniol + NAD(P)+ = geranial + NAD(P)H + H+
show the reaction diagram
-
geraniol = (R)-linalool + (S)-linalool
show the reaction diagram
-

In Vivo Product in Enzyme-catalyzed Reactions (6 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
geraniol acetate + H2O = geraniol + acetate
show the reaction diagram
-
geranyl diphosphate + H2O = geraniol + diphosphate
show the reaction diagram
-

Substrate in Enzyme-catalyzed Reactions (44 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
geraniol + NADP+ = ?
show the reaction diagram
-
geraniol + NAD+ = geranial + NADH + H+
show the reaction diagram
-
geraniol + NADP+ = geranial + NADPH + H+
show the reaction diagram
-
geraniol + glutathione + NAD+ = S-geranylglutathione + NADH
show the reaction diagram
-
geraniol + 2 NADP+ = ? + 2 NADPH + 2 H+
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-
geraniol + NAD+ = geranial + NADH + H+
show the reaction diagram
-
geraniol + NAD+ = geranial + NADH + H+
show the reaction diagram
-
geraniol + O2 = 3,7-dimethylocta-trans-2,6-dien-1-al + H2O2
show the reaction diagram
-
geraniol + ubiquinone = geranial + ubiquinol
show the reaction diagram
-
geraniol + Cl- + H2O2 = ?
show the reaction diagram
-
geraniol + [reduced NADPH-hemoprotein reductase] + O2 = 8-hydroxygeraniol + 10-hydroxygeraniol + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
-
geraniol + O2 + reduced adrenodoxin [iron-sulfur] cluster + H+ = ? + H2O + oxidized adrenodoxin [iron-sulfur] cluster
show the reaction diagram
-
ATP + geraniol = ADP + geranyl phosphate
show the reaction diagram
-
geraniol + hesperidin = geranyl beta-D-rutinoside + hesperetin
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (28 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
(2E)-3,7-dimethylocta-2,6-dienal + NADPH + H+ = (2E)-3,7-dimethylocta-2,6-dien-1-ol + NADP+
show the reaction diagram
-
geranial + NADPH + H+ = geraniol + NADP+
show the reaction diagram
-
geranyl acetate + H2O = geraniol + acetate
show the reaction diagram
-
geranyl acetate + H2O = geraniol + acetate
show the reaction diagram
-
geranyl diphosphate + H2O = geraniol + ?
show the reaction diagram
-
geranyl diphosphate + H2O = geraniol + diphosphate
show the reaction diagram
-
geranyl-diphosphate + H2O = geraniol + diphosphate
show the reaction diagram
-
geranyl diphosphate + H2O = geraniol + diphosphate
show the reaction diagram
-
sour cherry glycoside + H2O = benzaldehyde + eugenol + trans-isoeugenol + cis-isoeugenol + geraniol + ?
show the reaction diagram
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geranyl rutinoside + H2O = geraniol + 6-O-alpha-L-rhamnopyranosyl-beta-D-glucopyranoside
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geranyl-beta-D-glucopyranoside + H2O = geraniol + beta-D-glucose
show the reaction diagram
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muscat glycoside extract = linalool + alpha-terpineol + citronellol + nerol + geraniol + ?
show the reaction diagram
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(2E)-geranyl diphosphate + H2O = geraniol + diphosphate
show the reaction diagram
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geranyl diphosphate = geraniol + linalool + diphosphate
show the reaction diagram
-

Inhibitor in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
about 3% inhibition at 0.1 mM
-
21.1% inhibition at 1 mM
-
7.6% inhibition at 0.03 mM
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3D Structure of Enzyme-Ligand-Complex (PDB) (24 results)

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (18 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
0.033
-
at pH 7.4 and 37°C
0.567
-
in 0.1 M potassium phosphate, pH 7.4, at 25°C
20
-
pH 10, 25°C
2996
-
in 50 mM Tris-HCl (pH 8.5), at 22°C
2996
-
pH 8.5, 22°C
0.023
-
pH 7.4, 25°C, recombinant enzyme
0.1
-
-

KM Value (35 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.18
-
at pH 7.4 and 37°C
0.025
-
in 0.1 M potassium phosphate, pH 7.4, at 25°C
0.8
-
pH 10, 25°C
0.051
-
pH 8.5, 22°C
0.0041
-
pH 7.4, 25°C, recombinant enzyme
1.56
-
-
0.11
-
pH 9.0, 30°C
0.14
-
-
0.5
-
pH 9.0, 35°C
0.455
-
pH 8.0, 35°C

References & Links

Links to other databases for geraniol

ChEBI
PubChem
ChEBI
PubChem