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Literature summary for 1.14.14.83 extracted from

  • Collu, G.; Garcia, A.; Van der Heijden, R.; Verpoorte, R.
    Activity of the cytochrome P450 enzyme geraniol 10-hydroxylase and alkaloid production in plant cell cultures (2002), Plant Sci., 162, 165-172.
No PubMed abstract available
Search for more literature for 1.14.14.83

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
 Catharanthus roseus 16020
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
geraniol + [reduced NADPH-hemoprotein reductase] + O2 Catharanthus roseus
-
 (6E)-8-hydroxygeraniol + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?

Organism

Organism UniProt Comment Textmining
Catharanthus roseus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
58CrPM cell
-
 Catharanthus roseus
-
cell culture G10H activity is correlated to the ability of the cells to accumulate terpenoid indole alkaloids. Alkaloid induction medium induces the enzyme, overview Catharanthus roseus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
geraniol + [reduced NADPH-hemoprotein reductase] + O2
-
 Catharanthus roseus (6E)-8-hydroxygeraniol + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?

Synonyms

Synonyms Comment Organism
G10H
-
 Catharanthus roseus
geraniol 10-hydroxylase
-
 Catharanthus roseus

Expression

Organism Comment Expression
Catharanthus roseus alkaloid induction medium induces the enzyme, overview up

General Information

General Information Comment Organism
evolution the enzyme belongs to the cytochrome-P450 monooxygenase family Catharanthus roseus
metabolism the enzyme is involved in the 2-C-methyl-D-erythritol-4-phosphate/terpenoid metabolic pathway part of the iridoid pathway, overview. Induction of G10H is a requirement, but not the only, necessary to produce other terpenoid indole alkaloids than strictosidine Catharanthus roseus