Cloned (Comment) | Organism |
---|---|
expression in Saccharomyces cerevisiae | Catharanthus roseus |
Crystallization (Comment) | Organism |
---|---|
homology modeling. The geraniol molecule is positioned close to protoporphyrin with the double bond C6-C7 parallel to the heme plane | Catharanthus roseus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Catharanthus roseus | Q8VWZ7 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
geraniol + [reduced NADPH-hemoprotein reductase] + O2 | - |
Catharanthus roseus | (6E)-8-hydroxygeraniol + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
additional information | enzyme is a specialized multifunctional enzyme catalyzing two sequential oxidation steps leading to the formation of 8-oxogeraniol from geraniol. The first step, geraniol hydroxylation, is very efficient and fast enough to outcompete geraniol conjugation in plant tissues | Catharanthus roseus | ? | - |
? |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
2.8 | - |
geraniol | pH 7.4, 27°C | Catharanthus roseus |
General Information | Comment | Organism |
---|---|---|
physiological function | transient expression in Nicotiana benthamiana leaf leads to formation of 8-hydroxygeraniol and 8-oxogeraniol | Catharanthus roseus |