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Literature summary for 1.14.14.83 extracted from

  • Collu, G.; Bink, H.H.J.; Moreno, P.R.H.; van der Heijden, R.; Verpoorte, R.
    Determination of the activity of the cytochrome p450 enzyme geraniol 10-hydroxylase in plants by high-performance liquid chromatography (1999), Phytochem. Anal., 10, 314-318.
No PubMed abstract available
Search for more literature for 1.14.14.83

Inhibitors

Inhibitors Comment Organism Structure
cantharanthine feedback inhibition Catharanthus roseus

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
 Catharanthus roseus 16020
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
geraniol + [reduced NADPH-hemoprotein reductase] + O2 Catharanthus roseus
-
 10-hydroxygeraniol + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?
nerol + [reduced NADPH-hemoprotein reductase] + O2 Catharanthus roseus cis-isomer of geraniol 10-hydroxynerol + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?

Organism

Organism UniProt Comment Textmining
Catharanthus roseus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
geraniol + [reduced NADPH-hemoprotein reductase] + O2
-
 Catharanthus roseus 10-hydroxygeraniol + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?
geraniol + [reduced NADPH-hemoprotein reductase] + O2 development and validation of an HPLC detection method for quantification of geraniol and 10-hydroxygeraniol, with separation of geraniol and nerol, overview Catharanthus roseus 10-hydroxygeraniol + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?
nerol + [reduced NADPH-hemoprotein reductase] + O2 cis-isomer of geraniol Catharanthus roseus 10-hydroxynerol + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?

Synonyms

Synonyms Comment Organism
G10H
-
 Catharanthus roseus

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
30
-
 assay at Catharanthus roseus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.6
-
 assay at Catharanthus roseus

Cofactor

Cofactor Comment Organism Structure
cytochrome P450
-
 Catharanthus roseus
FAD
-
 Catharanthus roseus

General Information

General Information Comment Organism
physiological function the cytochrome P450 enzyme geraniol 10-hydroxylase plays an important role in the biosynthesis of pharmaceutically important alkaloids in Catharanthus roseus Catharanthus roseus