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Literature summary for 1.14.14.83 extracted from
- Cytochrome P-450 in plant/insect interactions: geraniol 10-hydroxylase and the biosynthesis of iridoid monoterpenoids (1995), Drug Metabol. Drug Interact., 12, 369-382.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| membrane | - |
Nepeta racemosa | 16020 | - |
| microsome | - |
Catharanthus roseus | - |
- |
| microsome | - |
Nepeta racemosa | - |
- |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| (R,S)-citronellol + [reduced NADPH-hemoprotein reductase] + O2 | Catharanthus roseus | - |
(6E)-8-hydroxycitronellol + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? |  |
| (R,S)-citronellol + [reduced NADPH-hemoprotein reductase] + O2 | Nepeta racemosa | - |
(6E)-8-hydroxycitronellol + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
| cis-nerol + [reduced NADPH-hemoprotein reductase] + O2 | Catharanthus roseus | - |
(6E)-8-hydroxynerol + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
| cis-nerol + [reduced NADPH-hemoprotein reductase] + O2 | Nepeta racemosa | - |
(6E)-8-hydroxynerol + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
| geraniol + [reduced NADPH-hemoprotein reductase] + O2 | Catharanthus roseus | - |
(6E)-8-hydroxygeraniol + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
| geraniol + [reduced NADPH-hemoprotein reductase] + O2 | Nepeta racemosa | - |
(6E)-8-hydroxygeraniol + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Catharanthus roseus | - |
- |
- |
| Nepeta racemosa | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| leaf | - |
Catharanthus roseus | - |
| leaf | - |
Nepeta racemosa | - |
| seedling | etiolated | Nepeta racemosa | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| (R,S)-citronellol + [reduced NADPH-hemoprotein reductase] + O2 | - |
Catharanthus roseus | (6E)-8-hydroxycitronellol + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
| (R,S)-citronellol + [reduced NADPH-hemoprotein reductase] + O2 | - |
Nepeta racemosa | (6E)-8-hydroxycitronellol + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
| (R,S)-citronellol + [reduced NADPH-hemoprotein reductase] + O2 | - |
Catharanthus roseus | (6E)-8-hydroxycitronellol + [oxidized NADPH-hemoprotein reductase] + H2O | GC-MS product analysis | ? | |
| (R,S)-citronellol + [reduced NADPH-hemoprotein reductase] + O2 | - |
Nepeta racemosa | (6E)-8-hydroxycitronellol + [oxidized NADPH-hemoprotein reductase] + H2O | GC-MS product analysis | ? | |
| cis-nerol + [reduced NADPH-hemoprotein reductase] + O2 | - |
Catharanthus roseus | (6E)-8-hydroxynerol + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
| cis-nerol + [reduced NADPH-hemoprotein reductase] + O2 | - |
Nepeta racemosa | (6E)-8-hydroxynerol + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
| cis-nerol + [reduced NADPH-hemoprotein reductase] + O2 | - |
Catharanthus roseus | (6E)-8-hydroxynerol + [oxidized NADPH-hemoprotein reductase] + H2O | GC-MS product analysis | ? | |
| cis-nerol + [reduced NADPH-hemoprotein reductase] + O2 | - |
Nepeta racemosa | (6E)-8-hydroxynerol + [oxidized NADPH-hemoprotein reductase] + H2O | GC-MS product analysis | ? | |
| geraniol + [reduced NADPH-hemoprotein reductase] + O2 | - |
Catharanthus roseus | (6E)-8-hydroxygeraniol + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
| geraniol + [reduced NADPH-hemoprotein reductase] + O2 | - |
Nepeta racemosa | (6E)-8-hydroxygeraniol + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
| geraniol + [reduced NADPH-hemoprotein reductase] + O2 | - |
Catharanthus roseus | (6E)-8-hydroxygeraniol + [oxidized NADPH-hemoprotein reductase] + H2O | GC-MS product analysis | ? | |
| geraniol + [reduced NADPH-hemoprotein reductase] + O2 | - |
Nepeta racemosa | (6E)-8-hydroxygeraniol + [oxidized NADPH-hemoprotein reductase] + H2O | GC-MS product analysis | ? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| G10H | - |
Catharanthus roseus |
| G10H | - |
Nepeta racemosa |
| geraniol 10-hydroxylase | - |
Catharanthus roseus |
| geraniol 10-hydroxylase | - |
Nepeta racemosa |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| cytochrome P450 | - |
Catharanthus roseus | |
| cytochrome P450 | - |
Nepeta racemosa |
General Information
| General Information | Comment | Organism |
|---|---|---|
| evolution | the enzyme is a cyt P450 monoterpene hydroxylase and belongs to the cytochrome-P450 monooxygenase family | Catharanthus roseus |
| evolution | the enzyme is a cyt P450 monoterpene hydroxylase and belongs to the cytochrome-P450 monooxygenase family | Nepeta racemosa |
| metabolism | the enzyme is involved in the biosynthesis of iridiod monoterpenoids | Catharanthus roseus |
| metabolism | the enzyme is involved in the biosynthesis of iridiod monoterpenoids | Nepeta racemosa |
| physiological function | the enzyme is involved in the biosynthesis of iridiod monoterpenoids, which are important in plant defense systems against herbivores | Catharanthus roseus |
| physiological function | the enzyme is involved in the biosynthesis of iridiod monoterpenoids, which are important in plant defense systems against herbivores | Nepeta racemosa |
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Release 2023.1 (January 2023)
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