Information on EC 2.7.11.20 - elongation factor 2 kinase

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The expected taxonomic range for this enzyme is: Eukaryota

EC NUMBER
COMMENTARY
2.7.11.20
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RECOMMENDED NAME
GeneOntology No.
elongation factor 2 kinase
REACTION
REACTION DIAGRAM
COMMENTARY
ORGANISM
UNIPROT ACCESSION NO.
LITERATURE
ATP + [elongation factor 2] = ADP + [elongation factor 2] phosphate
show the reaction diagram
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SYSTEMATIC NAME
IUBMB Comments
ATP:[elongation factor 2] phosphotransferase
Requires Ca2+ and calmodulin for activity. The enzyme can also be phosphorylated by the catalytic subunit of EC 2.7.11.11, cAMP-dependent protein kinase. Elongation factor 2 is phosphorylated in several cell types in response to various growth factors, hormones and other stimuli that raise intracellular Ca2+ [1,2].
SYNONYMS
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
Ca2+/calmodulin-dependent kinase III
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Ca2+/calmodulin–dependent kinase III
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eEF-2 kinase
-
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eEF-2 kinase
-
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eEF-2 kinase
-
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EEF-2K
O00418
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EEF-2K
-
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EEF-2K
Q08796
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eEF2 kinase
-
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eEF2 kinase
Q00418
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eEF2 kinase
-
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eEF2-kinase
-
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eEF2K
F8S834
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eEF2K
Q00418
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EF-2K
O00418
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eIF2alpha kinase
-
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elongation factor 2 kinase
O01991
-
elongation factor 2 kinase
O00418
-
elongation factor 2 kinase
O08796
-
elongation factor 2 kinase
P70531
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elongation factor-2 kinase
-
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eukaryotic elongation factor 2 kinase
-
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eukaryotic elongation factor 2 kinase
-
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eukaryotic elongation factor 2 kinase
-
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eukaryotic elongation factor-2 kinase
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eukaryotic elongation factor-2 kinase
-
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eukaryotic translation initiation factor 2alpha kinase
-
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GCN2
-
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GCN2
Mus musculus C57BL/6J
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-
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GCN2 eIF2alpha kinase
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GCN2 eIF2alpha kinase
Mus musculus C57BL/6J
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GCN2 kinase
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GCN2 kinase
Mus musculus C57BL/6J
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-
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general control nonderepressible 2 kinase
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general control nonderepressible 2 kinase
Mus musculus C57BL/6J
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additional information
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formerly CaMKIII
additional information
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MHCKs and eEF-2Ks comprise a distinct subgroup within the alpha kinase famiily
CAS REGISTRY NUMBER
COMMENTARY
116283-83-1
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ORGANISM
COMMENTARY
LITERATURE
SEQUENCE CODE
SEQUENCE DB
SOURCE
male humans of about 25 years
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Manually annotated by BRENDA team
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SwissProt
Manually annotated by BRENDA team
; C57BL/6J mice
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Manually annotated by BRENDA team
C57BLKsJ lepr-/-db/db mice, diabetc mice
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-
Manually annotated by BRENDA team
gene eEF-2K
UniProt
Manually annotated by BRENDA team
Mus musculus C57BL/6J
C57BL/6J mice
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-
Manually annotated by BRENDA team
male Sprague-Dawley rat
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Manually annotated by BRENDA team