Ontology explorer

Gene ontology
Version 2014-12-22
use AND (NOT) or OR
use AND (NOT) or OR
restrict to BRENDA links:
75 different search results found


Details for negative regulation of biological process
Gene ontology ID
GO:0048519
Definition
Any process that stops, prevents, or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule
Synonyms
1. down regulation of biological process
2. down-regulation of biological process
3. downregulation of biological process
4. inhibition of biological process
5. negative regulation of physiological process
References
1. GOC: jid
Legend
is an element of the parent element
is a part of the parent element
is related to the parent element
derives from the parent element
// at least 1 tissue/ enzyme/ localization link in this branch
// tissue/ enzyme/ localization link to BRENDA
Condensed Tree View
Gene ontology
biological_process is a
biological regulation is a
regulation of biological process is a
negative regulation of biological process is a
positive regulation of biological process is a
positive regulation of cellular process is a
positive regulation of cellular component organization is a
positive regulation of organelle organization is a
positive regulation of cellular protein localization is a
positive regulation of intracellular protein transport is a
regulation of cellular process is a
regulation of cellular component organization is a
regulation of organelle organization is a
signal transduction is a
regulation of localization is a
regulation of cellular localization is a
regulation of cellular protein localization is a
regulation of intracellular protein transport is a
regulation of protein targeting is a
regulation of biological quality is a
maintenance of location is a
maintenance of location in cell is a
maintenance of protein location in cell is a
maintenance of protein localization in organelle is a
cellular component organization or biogenesis is a
cellular component biogenesis is a
cellular component assembly part of
protein-containing complex assembly is a
cellular protein-containing complex assembly is a
proton-transporting two-sector ATPase complex assembly is a
proton-transporting ATP synthase complex assembly is a
ribonucleoprotein complex biogenesis is a
ribosome biogenesis is a
rRNA processing part of
cellular component organization is a
cellular component disassembly is a
organelle disassembly is a
organelle organization is a
organelle fission is a
plastid fission is a
plastid organization is a
chloroplast organization is a
chloroplast relocation is a
cellular process is a
cellular metabolic process is a
cellular aromatic compound metabolic process is a
nucleobase-containing compound metabolic process is a
nucleic acid metabolic process is a
RNA metabolic process is a
mRNA metabolic process is a
mRNA modification is a
mRNA processing is a
RNA modification is a
RNA processing is a
membrane docking is a
organelle localization by membrane tethering is a
localization is a
cellular localization is a
cellular macromolecule localization is a
cellular protein localization is a
intracellular protein transport part of
intracellular protein transmembrane transport is a
protein targeting is a
protein localization to organelle is a
establishment of protein localization to organelle is a
protein localization to chloroplast is a
intracellular transport is a
endoplasmic reticulum to chloroplast transport is a
organelle localization is a
plastid localization is a
establishment of localization is a
transport is a
transmembrane transport is a
transmembrane transporter activity part of
active transmembrane transporter activity is a
primary active transmembrane transporter activity is a
ATPase-coupled transmembrane transporter activity is a
ATPase-coupled protein transmembrane transporter activity is a
multi-organism process is a
interspecies interaction between organisms is a
modification of morphology or physiology of other organism is a
modification of morphology or physiology of other organism involved in symbiotic interaction is a
modification by symbiont of host morphology or physiology is a
modification by symbiont of host structure is a
modification by symbiont of host cellular component is a
modification by symbiont of host chloroplast is a
modification by symbiont of host chloroplast part is a
cellular_component is a
cellular anatomical entity is a
cytoplasm is a425 BRENDA localization in branch, click for list of all
ADPG pyrophosphorylase complex part of
heterotetrameric ADPG pyrophosphorylase complex is a
plastid ADPG pyrophosphorylase complex is a
cytoplasmic chromosome part of
plastid chromosome is a160 BRENDA localization in branch, click for list of all
plastid part of72 BRENDA localization in branch, click for list of all
chloroplast is a36 BRENDA localization in branch, click for list of all
chloroplast envelope part of15 BRENDA localization in branch, click for list of all
chloroplast membrane part of13 BRENDA localization in branch, click for list of all
chloroplast inner membrane is a
intrinsic component of chloroplast inner membrane part of
chloroplast outer membrane is a12 BRENDA localization in branch, click for list of all
intrinsic component of chloroplast outer membrane part of
chloroplast stroma part of10 BRENDA localization in branch, click for list of all
chloroplast ribosome part of
chloroplast thylakoid part of6 BRENDA localization in branch, click for list of all
chloroplast thylakoid membrane part of3 BRENDA localization in branch, click for list of all
chloroplast thylakoid membrane protein complex part of
chloroplast proton-transporting ATP synthase complex is a
signal recognition particle part of22 BRENDA localization in branch, click for list of all
host cellular component is a
host cell is a13 BRENDA localization in branch, click for list of all
host cell part part of
host cell membrane is a11 BRENDA localization in branch, click for list of all
host thylakoid membrane is a
host intracellular part is a
host cell cytoplasm is a2 BRENDA localization in branch, click for list of all
host cell cytoplasm part part of
host cell plastid is a
host cell chloroplast is a
molecular_function is a
binding is a
amide binding is a
peptide binding is a
signal sequence binding is a
protein-containing complex binding is a
Tree view
Gene ontology
biological_process is a
behavior is a
biological adhesion is a
biological phase is a
biological regulation is a
regulation of biological process is a
negative regulation of biological process is a
negative regulation of 3'-UTR-mediated mRNA stabilization is a
negative regulation of action potential is a
negative regulation of asexual reproduction is a
negative regulation of biomineralization is a
negative regulation of cell killing is a
negative regulation of cellular process is a
negative regulation of actin filament severing is a
negative regulation of binding of sperm to zona pellucida is a
negative regulation of calcium ion export across plasma membrane is a
negative regulation of calcium ion transport into cytosol is a
negative regulation of cell activation is a
negative regulation of cell adhesion molecule production is a
negative regulation of cell aging is a
negative regulation of cell communication is a
negative regulation of cell cycle is a
negative regulation of cell death is a
negative regulation of cell differentiation is a
negative regulation of cell division is a
negative regulation of cell growth is a
negative regulation of cell population proliferation is a
negative regulation of cell wall organization or biogenesis is a
negative regulation of cellular component movement is a
negative regulation of cellular component organization is a
negative regulation of adherens junction organization is a
negative regulation of barbed-end actin filament capping is a
negative regulation of blood microparticle formation is a
negative regulation of capsule organization is a
negative regulation of cell junction assembly is a
negative regulation of cell projection organization is a
negative regulation of clathrin-coated pit assembly is a
negative regulation of endocytosis is a
negative regulation of extracellular matrix organization is a
negative regulation of fusion of sperm to egg plasma membrane is a
negative regulation of fusion of virus membrane with host plasma membrane is a
negative regulation of hyaluranon cable assembly is a
negative regulation of inclusion body assembly is a
negative regulation of integrin biosynthetic process is a
negative regulation of iron-sulfur cluster assembly is a
negative regulation of membrane invagination is a
negative regulation of membrane tubulation is a
negative regulation of organelle organization is a
negative regulation of cargo loading into COPII-coated vesicle is a
negative regulation of chloroplast fission is a
negative regulation of chromosome organization is a
negative regulation of cytoskeleton organization is a
negative regulation of endoplasmic reticulum tubular network organization is a
negative regulation of endosome organization is a
negative regulation of lysosome organization is a
negative regulation of melanosome organization is a
negative regulation of mitochondrion organization is a
negative regulation of nuclear division is a
negative regulation of organelle assembly is a
negative regulation of phagosome maturation is a
negative regulation of postsynaptic density organization is a
negative regulation of secretory granule organization is a
negative regulation of synaptic vesicle lumen acidification is a
negative regulation of vacuole fusion, non-autophagic is a
negative regulation of vesicle fusion is a
negative regulation of phospholipid translocation is a
negative regulation of plasma lipoprotein oxidation is a
negative regulation of plasma membrane raft polarization is a
negative regulation of plasma membrane repair is a
negative regulation of protein complex assembly is a
negative regulation of protein complex disassembly is a
negative regulation of supramolecular fiber organization is a
negative regulation of synapse organization is a
negative regulation of synapse structural plasticity is a
negative regulation of synaptic vesicle membrane organization is a
negative regulation of syncytium formation by plasma membrane fusion is a
negative regulation of tight junction disassembly is a
negative regulation of very-low-density lipoprotein particle remodeling is a
negative regulation of vitellogenesis is a
negative regulation of cellular hyperosmotic salinity response is a
negative regulation of cellular metabolic process is a
negative regulation of cellular pH reduction is a
negative regulation of cellular response to alcohol is a
negative regulation of cellular response to alkaline pH is a
negative regulation of cellular response to drug is a
negative regulation of cellular response to gamma radiation is a
negative regulation of cellular response to growth factor stimulus is a
negative regulation of cellular response to heat is a
negative regulation of cellular response to hypoxia is a
negative regulation of cellular response to insulin stimulus is a
negative regulation of cellular response to macrophage colony-stimulating factor stimulus is a
negative regulation of cellular response to manganese ion is a
negative regulation of cellular response to oxidative stress is a
negative regulation of cellular response to oxidopamine is a
negative regulation of cellular response to testosterone stimulus is a
negative regulation of cellular response to thapsigargin is a
negative regulation of cellular response to tunicamycin is a
negative regulation of cellular response to very-low-density lipoprotein particle stimulus is a
negative regulation of cellular response to X-ray is a
negative regulation of chromosome segregation is a
negative regulation of conjugation is a
negative regulation of cytolysis is a
negative regulation of dense core granule biogenesis is a
negative regulation of early endosome to late endosome transport is a
negative regulation of endocytic recycling is a
negative regulation of establishment of bipolar cell polarity is a
negative regulation of establishment or maintenance of cell polarity regulating cell shape is a
negative regulation of gene silencing is a
negative regulation of Golgi to plasma membrane protein transport is a
negative regulation of iron export across plasma membrane is a
negative regulation of iron ion import across plasma membrane is a
negative regulation of melanosome transport is a
negative regulation of myelination is a
negative regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization is a
negative regulation of peroxidase activity is a
negative regulation of phenotypic switching is a
negative regulation of potassium ion export across plasma membrane is a
negative regulation of protein folding is a
negative regulation of response to DNA damage stimulus is a
negative regulation of response to endoplasmic reticulum stress is a
negative regulation of ribosome biogenesis is a
negative regulation of secretion by cell is a
negative regulation of sequestering of calcium ion is a
negative regulation of sequestering of zinc ion is a
negative regulation of single-species biofilm formation is a
negative regulation of sodium ion export across plasma membrane is a
negative regulation of stomatal opening is a
negative regulation of transposition is a
negative regulation of vesicle docking is a
negative regulation of xenobiotic detoxification by transmembrane export across the plasma membrane is a
negative regulation of cellular protein localization is a
negative regulation of circadian rhythm is a
negative regulation of developmental pigmentation is a
negative regulation of developmental process is a
negative regulation of DNA-binding transcription factor activity is a
negative regulation of dosage compensation by inactivation of X chromosome is a
negative regulation of establishment of protein localization is a
negative regulation of establishment of RNA localization to telomere is a
negative regulation of fibrinolysis is a
negative regulation of growth is a
negative regulation of GTPase activity is a
negative regulation of guanyl-nucleotide exchange factor activity is a
negative regulation of hemostasis is a
negative regulation of immune system process is a
negative regulation of interphase mitotic telomere clustering is a
negative regulation of intracellular mRNA localization is a
negative regulation of lipid localization is a
negative regulation of locomotion is a
negative regulation of long-term synaptic potentiation is a
negative regulation of maintenance of permeability of blood-brain barrier is a
negative regulation of membrane depolarization is a
negative regulation of membrane hyperpolarization is a
negative regulation of metabolic process is a
negative regulation of mitotic telomere tethering at nuclear periphery is a
negative regulation of multi-organism process is a
negative regulation of multicellular organismal process is a
negative regulation of nitrogen utilization is a
negative regulation of nuclear receptor transcription coactivator activity is a
negative regulation of phosphorus utilization is a
negative regulation of proteasome-activating ATPase activity is a
negative regulation of protein localization to cell-cell adherens junction is a
negative regulation of protein localization to presynapse is a
negative regulation of receptor localization to synapse is a
negative regulation of reproductive process is a
negative regulation of response to stimulus is a
negative regulation of ribonucleoprotein complex localization is a
negative regulation of short-term synaptic potentiation is a
negative regulation of signaling is a
negative regulation of sulfur utilization is a
negative regulation of telomerase RNA localization to Cajal body is a
negative regulation of transport is a
positive regulation of biological process is a
positive regulation of action potential is a
positive regulation of asexual reproduction is a
positive regulation of biomineralization is a
positive regulation of cell killing is a
positive regulation of cellular component biogenesis is a
positive regulation of cellular process is a
positive regulation of actin filament severing is a
positive regulation of calcium ion export across plasma membrane is a
positive regulation of calcium ion transport into cytosol is a
positive regulation of cell activation is a
positive regulation of cell adhesion molecule production is a
positive regulation of cell aging is a
positive regulation of cell communication is a
positive regulation of cell cycle is a
positive regulation of cell death is a
positive regulation of cell differentiation is a
positive regulation of cell division is a
positive regulation of cell growth is a
positive regulation of cell population proliferation is a
positive regulation of cell wall organization or biogenesis is a
positive regulation of cellular component movement is a
positive regulation of cellular component organization is a
positive regulation of adherens junction organization is a
positive regulation of blood microparticle formation is a
positive regulation of capsule organization is a
positive regulation of cell projection organization is a
positive regulation of chylomicron remodeling is a
positive regulation of endocytosis is a
positive regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation is a
positive regulation of extracellular matrix organization is a
positive regulation of fusion of virus membrane with host plasma membrane is a
positive regulation of integrin biosynthetic process is a
positive regulation of membrane invagination is a
positive regulation of membrane tubulation is a
positive regulation of neuromuscular junction development is a
positive regulation of organelle organization is a
positive regulation of autophagosome maturation is a
positive regulation of chloroplast fission is a
positive regulation of chromosome organization is a
positive regulation of cytoskeleton organization is a
positive regulation of endoplasmic reticulum tubular network organization is a
positive regulation of endosome organization is a
positive regulation of melanosome organization is a
positive regulation of mitochondrion organization is a
positive regulation of nuclear division is a
positive regulation of peroxisome organization is a
positive regulation of phagosome maturation is a
positive regulation of postsynaptic density organization is a
positive regulation of secretory granule organization is a
positive regulation of synaptic vesicle lumen acidification is a
positive regulation of vacuole organization is a
positive regulation of vesicle fusion is a
positive regulation of phospholipid translocation is a
positive regulation of plasma membrane raft polarization is a
positive regulation of plasma membrane repair is a
positive regulation of postsynaptic membrane organization is a
positive regulation of presynaptic membrane organization is a
positive regulation of protein complex disassembly is a
positive regulation of supramolecular fiber organization is a
positive regulation of synapse maturation is a
positive regulation of synapse pruning is a
positive regulation of synapse structural plasticity is a
positive regulation of synaptic vesicle membrane organization is a
positive regulation of syncytium formation by plasma membrane fusion is a
positive regulation of terminal button organization is a
positive regulation of tight junction disassembly is a
positive regulation of very-low-density lipoprotein particle remodeling is a
positive regulation of vitellogenesis is a
positive regulation of cellular metabolic process is a
positive regulation of cellular pH reduction is a
positive regulation of cellular response to alcohol is a
positive regulation of cellular response to drug is a
positive regulation of cellular response to gamma radiation is a
positive regulation of cellular response to heat is a
positive regulation of cellular response to hepatocyte growth factor stimulus is a
positive regulation of cellular response to hypoxia is a
positive regulation of cellular response to insulin stimulus is a
positive regulation of cellular response to macrophage colony-stimulating factor stimulus is a
positive regulation of cellular response to manganese ion is a
positive regulation of cellular response to oxidative stress is a
positive regulation of cellular response to oxidopamine is a
positive regulation of cellular response to thapsigargin is a
positive regulation of cellular response to transforming growth factor beta stimulus is a
positive regulation of cellular response to tunicamycin is a
positive regulation of cellular response to very-low-density lipoprotein particle stimulus is a
positive regulation of cellular response to X-ray is a
positive regulation of chromosome segregation is a
positive regulation of conjugation is a
positive regulation of cytolysis is a
positive regulation of early endosome to late endosome transport is a
positive regulation of endocytic recycling is a
positive regulation of establishment of bipolar cell polarity is a
positive regulation of establishment or maintenance of cell polarity regulating cell shape is a
positive regulation of Golgi to plasma membrane protein transport is a
positive regulation of iron export across plasma membrane is a
positive regulation of iron ion import across plasma membrane is a
positive regulation of melanosome transport is a
positive regulation of myelination is a
positive regulation of peroxidase activity is a
positive regulation of phenotypic switching is a
positive regulation of potassium ion export across plasma membrane is a
positive regulation of protein folding is a
positive regulation of response to cell cycle checkpoint signaling is a
positive regulation of response to DNA damage stimulus is a
positive regulation of response to endoplasmic reticulum stress is a
positive regulation of secretion by cell is a
positive regulation of sequestering of calcium ion is a
positive regulation of sequestering of zinc ion is a
positive regulation of single-species biofilm formation is a
positive regulation of sodium ion export across plasma membrane is a
positive regulation of stomatal opening is a
positive regulation of transposition is a
positive regulation of vesicle docking is a
positive regulation of xenobiotic detoxification by transmembrane export across the plasma membrane is a
positive regulation of cellular protein localization is a
positive regulation of establishment of protein localization to mitochondrion is a
positive regulation of intracellular protein transport is a
positive regulation of endosome to plasma membrane protein transport is a
positive regulation of protein exit from endoplasmic reticulum is a
positive regulation of protein export from nucleus is a
positive regulation of protein import into chloroplast stroma is a
positive regulation of protein import into nucleus is a
positive regulation of protein targeting to membrane is a
positive regulation of protein localization to cell leading edge is a
positive regulation of protein localization to cell periphery is a
positive regulation of protein localization to cell surface is a
positive regulation of protein localization to cell tip is a
positive regulation of protein localization to centrosome is a
positive regulation of protein localization to chromatin is a
positive regulation of protein localization to chromosome, telomeric region is a
positive regulation of protein localization to cilium is a
positive regulation of protein localization to endoplasmic reticulum is a
positive regulation of protein localization to endosome is a
positive regulation of protein localization to kinetochore is a
positive regulation of protein localization to lysosome is a
positive regulation of protein localization to membrane is a
positive regulation of protein localization to nucleus is a
positive regulation of protein localization to phagocytic vesicle is a
positive regulation of protein localization to spindle pole body is a
positive regulation of circadian rhythm is a
positive regulation of developmental pigmentation is a
positive regulation of developmental process is a
positive regulation of DNA-binding transcription factor activity is a
positive regulation of dosage compensation by inactivation of X chromosome is a
positive regulation of establishment of protein localization is a
positive regulation of establishment of RNA localization to telomere is a
positive regulation of growth is a
positive regulation of guanyl-nucleotide exchange factor activity is a
positive regulation of hemostasis is a
positive regulation of immune system process is a
positive regulation of intracellular mRNA localization is a
positive regulation of lipid localization is a
positive regulation of locomotion is a
positive regulation of maintenance of permeability of blood-brain barrier is a
positive regulation of membrane depolarization is a
positive regulation of membrane hyperpolarization is a
positive regulation of metabolic process is a
positive regulation of multi-organism process is a
positive regulation of multicellular organismal process is a
positive regulation of nitrogen utilization is a
positive regulation of phosphorus utilization is a
positive regulation of protein localization to cell-cell junction is a
positive regulation of protein localization to synapse is a
positive regulation of reproductive process is a
positive regulation of response to stimulus is a
positive regulation of ribonucleoprotein complex localization is a
positive regulation of short-term synaptic potentiation is a
positive regulation of signaling is a
positive regulation of sulfur utilization is a
positive regulation of telomerase RNA localization to Cajal body is a