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Version 2014-12-22
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Details for 1-pyrroline-5-carboxylate dehydrogenase activity
1.2.1.88
Gene ontology ID
GO:0003842
Definition
Catalysis of the reaction: 1-pyrroline-5-carboxylate + NAD+ + H2O = L-glutamate + NADH + H(+)
Synonyms
1. 1-pyrroline dehydrogenase
2. 1-pyrroline-5-carboxylate:NAD+ oxidoreductase activity
3. delta1-pyrroline-5-carboxylate dehydrogenase activity
4. L-pyrroline-5-carboxylate-NAD+ oxidoreductase activity
5. pyrroline-5-carboxylate dehydrogenase activity
6. pyrroline-5-carboxylic acid dehydrogenase activity
References
1. EC 1.2.1.88
2. MetaCyc PYRROLINECARBDEHYDROG-RXN
3. Reactome: R-HSA-6784399 "ALDH4A1 dimer dehydrogenates 4-OH-L-glutamate semialdehyde to 4-OH-L-glutamate"
4. Reactome: R-HSA-70679 "ALDH4A1 oxidises L-GluSS to Glu"
5. RHEA: 16417
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