Reference on EC 3.1.1.79 - hormone-sensitive lipase and Organism(s) Homo sapiens
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AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Yeaman, S.J.
Hormone-sensitive lipase - new roles for an old enzyme
Biochem. J.
379
11-22
2004
Homo sapiens, Mus musculus, Rattus norvegicus
Remaury, A.; Laurell, H.; Grober, J.; Reynisdottir, S.; Dauzats, M.; Holm, C.; Langin, D.
Expression of hormone-sensitive lipase in the human colon adenocarcinoma cell line HT29
Biochem. Biophys. Res. Commun.
207
175-182
1995
Homo sapiens
Mairal, A.; Melaine, N.; Laurell, H.; Grober, J.; Holst, L.S.; Guillaudeux, T.; Holm, C.; Jegou, B.; Langin, D.
Characterization of a novel testicular form of human hormone-sensitive lipase
Biochem. Biophys. Res. Commun.
291
286-290
2002
Homo sapiens
Ben Ali, Y.; Chahinian, H.; Petry, S.; Muller, G.; Carriere, F.; Verger, R.; Abousalham, A.
Might the kinetic behavior of hormone-sensitive lipase reflect the absence of the lid domain?
Biochemistry
43
9298-9306
2004
Homo sapiens
Holm, C.; Belfrage, P.; Fredrikson, G.
Human adipose tissue hormone-sensitive lipase: identification and comparison with other species
Biochim. Biophys. Acta
1006
193-197
1989
Homo sapiens, Rattus norvegicus
Osterlund, T.
Structure-function relationships of hormone-sensitive lipase
Eur. J. Biochem.
268
1899-1907
2001
Homo sapiens, Mus musculus, Rattus norvegicus
Raclot, T.; Holm, C.; Langin, D.
Fatty acid specificity of hormone-sensitive lipase: implication in the selective hydrolysis of triacylglycerols
J. Lipid Res.
42
2049-2057
2001
Homo sapiens, Rattus norvegicus
Chahinian, H.; Ali, Y.B.; Abousalham, A.; Petry, S.; Mandrich, L.; Manco, G.; Canaan, S.; Sarda, L.
Substrate specificity and kinetic properties of enzymes belonging to the hormone-sensitive lipase family: comparison with non-lipolytic and lipolytic carboxylesterases
Biochim. Biophys. Acta
1738
29-36
2005
Homo sapiens
De Jong, J.C.; Sorensen, L.G.; Tornqvist, H.; Jacobsen, P.
Carbazates as potent inhibitors of hormone-sensitive lipase
Bioorg. Med. Chem. Lett.
14
1741-1744
2004
Homo sapiens
O'Neill, M.; Watt, M.J.; Heigenhauser, G.J.; Spriet, L.L.
Effects of reduced free fatty acid availability on hormone-sensitive lipase activity in human skeletal muscle during aerobic exercise
J. Appl. Physiol.
97
1938-1945
2004
Homo sapiens
Ben Ali, Y.; Carriere, F.; Verger, R.; Petry, S.; Muller, G.; Abousalham, A.
Continuous monitoring of cholesterol oleate hydrolysis by hormone-sensitive lipase and other cholesterol esterases
J. Lipid Res.
46
994-1000
2005
Homo sapiens
Claus, T.H.; Lowe, D.B.; Liang, Y.; Salhanick, A.I.; Lubeski, C.K.; Yang, L.; Lemoine, L.; Zhu, J.; Clairmont, K.B.
Specific inhibition of hormone-sensitive lipase improves lipid profile while reducing plasma glucose
J. Pharmacol. Exp. Ther.
315
1396-1402
2005
Homo sapiens
Roepstorff, C.; Vistisen, B.; Donsmark, M.; Nielsen, J.N.; Galbo, H.; Green, K.A.; Hardie, D.G.; Wojtaszewski, J.F.; Richter, E.A.; Kiens, B.
Regulation of hormone-sensitive lipase activity and Ser563 and Ser565 phosphorylation in human skeletal muscle during exercise
J. Physiol.
560
551-562
2004
Homo sapiens
Watt, M.J.; Spriet, L.L.
Regulation and role of hormone-sensitive lipase activity in human skeletal muscle
Proc. Nutr. Soc.
63
315-322
2004
Homo sapiens
Roepstorff, C.; Donsmark, M.; Thiele, M.; Vistisen, B.; Stewart, G.; Vissing, K.; Schjerling, P.; Hardie, D.G.; Galbo, H.; Kiens, B.
Sex differences in hormone-sensitive lipase expression, activity, and phosphorylation in skeletal muscle at rest and during exercise
Am. J. Physiol. Endocrinol. Metab.
291
E1106-E1114
2006
Homo sapiens
Ryden, M.; Jocken, J.; van Harmelen, V.; Dicker, A.; Hoffstedt, J.; Wiren, M.; Blomqvist, L.; Mairal, A.; Langin, D.; Blaak, E.; Arner, P.
Comparative studies of the role of hormone-sensitive lipase and adipose triglyceride lipase in human fat cell lipolysis
Am. J. Physiol. Endocrinol. Metab.
292
E1847-E1855
2007
Homo sapiens (Q05469), Homo sapiens
Aboulaich, N.; Ortegren, U.; Vener, A.V.; Stralfors, P.
Association and insulin regulated translocation of hormone-sensitive lipase with PTRF
Biochem. Biophys. Res. Commun.
350
657-661
2006
Homo sapiens
Palin, S.L.; McTernan, P.G.; McGee, K.C.; Sturdee, D.W.; Barnett, A.H.; Kumar, S.
Dydrogesterone and norethisterone regulate expression of lipoprotein lipase and hormone-sensitive lipase in human subcutaneous abdominal adipocytes
Diabetes Obes. Metab.
9
585-590
2007
Homo sapiens
Helge, J.W.; Biba, T.O.; Galbo, H.; Gaster, M.; Donsmark, M.
Muscle triacylglycerol and hormone-sensitive lipase activity in untrained and trained human muscles
Eur. J. Appl. Physiol.
97
566-572
2006
Homo sapiens
Smith, A.J.; Thompson, B.R.; Sanders, M.A.; Bernlohr, D.A.
Interaction of the adipocyte fatty acid-binding protein with the hormone-sensitive lipase: regulation by fatty acids and phosphorylation
J. Biol. Chem.
282
32424-32432
2007
Homo sapiens
Fernandez, C.; Hansson, O.; Nevsten, P.; Holm, C.; Klint, C.
Hormone-sensitive lipase is necessary for normal mobilization of lipids during submaximal exercise
Am. J. Physiol. Endocrinol. Metab.
295
E179-E186
2008
Homo sapiens (Q05469)
Jocken, J.W.; Roepstorff, C.; Goossens, G.H.; van der Baan, P.; van Baak, M.; Saris, W.H.; Kiens, B.; Blaak, E.E.
Hormone-sensitive lipase serine phosphorylation and glycerol exchange across skeletal muscle in lean and obese subjects: effect of beta-adrenergic stimulation
Diabetes
57
1834-1841
2008
Homo sapiens
Krintel, C.; Osmark, P.; Larsen, M.R.; Resjoe, S.; Logan, D.T.; Holm, C.
Ser649 and Ser650 are the major determinants of protein kinase A-mediated activation of human hormone-sensitive lipase against lipid substrates
PLoS ONE
3
e3756
2008
Homo sapiens (Q05469), Homo sapiens
Minkkilä, A.; Savinainen, J.; Käsnänen, H.; Xhaard, H.; Nevalainen, T.; Laitinen, J.; Poso, A.; Leppänen, J.; Saario, S.
Screening of various hormone-sensitive lipase inhibitors as endocannabinoid-hydrolyzing enzyme inhibitors
ChemMedChem
4
1253-1259
2009
Homo sapiens
Rodriguez, J.; Ben Ali, Y.; Abdelkafi, S.; Mendoza, L.; Leclaire, J.; Fotiadu, F.; Buono, G.; Carrière, F.; Abousalham, A.
In vitro stereoselective hydrolysis of diacylglycerols by hormone-sensitive lipase
Biochim. Biophys. Acta
1801
77-83
2010
Homo sapiens
Tanigawa, K.; Degang, Y.; Kawashima, A.; Akama, T.; Yoshihara, A.; Ishido, Y.; Makino, M.; Ishii, N.; Suzuki, K.
Essential role of hormone-sensitive lipase (HSL) in the maintenance of lipid storage in Mycobacterium leprae-infected macrophages
Microb. Pathog.
52
285-291
2012
Homo sapiens
Ogiyama, T.; Yamaguchi, M.; Kurikawa, N.; Honzumi, S.; Yamamoto, Y.; Sugiyama, D.; Takakusa, H.; Inoue, S.I.
Identification of a novel hormone sensitive lipase inhibitor with a reduced potential of reactive metabolites formation
Bioorg. Med. Chem.
25
2234-2243
2017
Homo sapiens
Ogiyama, T.; Yamaguchi, M.; Kurikawa, N.; Honzumi, S.; Terayama, K.; Nagaoka, N.; Yamamoto, Y.; Kimura, T.; Sugiyama, D.; Inoue, S.I.
Design, synthesis, and pharmacological evaluation of a novel series of hormone sensitive lipase inhibitor
Bioorg. Med. Chem.
25
4817-4828
2017
Homo sapiens
Whytock, K.L.; Shepherd, S.O.; Wagenmakers, A.J.M.; Strauss, J.A.
Hormone-sensitive lipase preferentially redistributes to lipid droplets associated with perilipin-5 in human skeletal muscle during moderate-intensity exercise
J. Physiol.
596
2077-2090
2018
Homo sapiens (Q05469), Homo sapiens
