1.1.2.10: lanthanide-dependent methanol dehydrogenase
This is an abbreviated version!
For detailed information about lanthanide-dependent methanol dehydrogenase, go to the full flat file.
Word Map on EC 1.1.2.10
-
1.1.2.10
-
xoxfs
-
methanotrophs
-
methane
-
formaldehyde
-
pyrroloquinoline
-
extorquens
-
fumariolicum
-
methylotrophy
-
lanthanum
-
methylobacterium
-
methylacidiphilum
-
pqq
-
pqq-dependent
-
mxafis
-
rare-earth
-
methylorubrum
-
volcanic
-
neodymium
-
methane-utilizing
-
ceiii
-
buryatense
-
praseodymium
-
quinoproteins
-
verrucomicrobial
-
geothermal
-
methylophilaceae
- 1.1.2.10
-
xoxfs
- methanotrophs
- methane
- formaldehyde
-
pyrroloquinoline
- extorquens
- fumariolicum
-
methylotrophy
- lanthanum
- methylobacterium
- methylacidiphilum
- pqq
-
pqq-dependent
-
mxafis
-
rare-earth
-
methylorubrum
-
volcanic
- neodymium
-
methane-utilizing
-
ceiii
- buryatense
-
praseodymium
-
quinoproteins
-
verrucomicrobial
-
geothermal
- methylophilaceae
Reaction
Synonyms
Ce-MDH, Ce-XoxF, Ce3+-dependent XoxF1-MDH, Ce3+-induced methanol dehydrogenase, cerium dependent MDH, cerium-dependent methanol dehydrogenase, Eu-MDH, exaF, La-XoxF, La2+-MDH-like protein, La3+-dependent MDH, La3+-dependent methanol dehydrogenase, La3+-induced methanol dehydrogenase-like protein, lanthanide-dependent alcohol dehydrogenase, lanthanide-dependent MDH, lanthanide-dependent MeDH, lanthanide-dependent methanol dehydrogenase, lanthanide-dependent quinoid alcohol dehydrogenase, lanthanide-dependent XoxF-type MDH, lanthanide-dependent XoxF-type methanol dehydrogenase, lanthanidedependent XoxF-MDH, lanthanides-dependent MDH, lanthanoid-dependent methanol dehydrogenase, Ln-dependent EtDH, Ln-dependent ethanol dehydrogenase, Ln-dependent MDH, Ln-dependent MetDH, Ln-dependent methanol dehydrogenase, Ln-MDH, methanol dehydrogenase, Nd-XoxF, pyrroloquinoline quinone ethanol dehydrogenase, quinoprotein ethanol dehydrogenase, XoxF, XoxF dehydrogenase, XoxF methanol dehydrogenase, XoxF-MDH, XoxF-type MDH, XoxF-type methanol dehydrogenase, xoxF1, XoxF4-1, XoxF4-2, XoxF5, XoxF5-1, XoxF5-2, XoxF5-type MDH, XoxFMDH, XoxFMeDH, XoxJ
ECTree
1.1.2.10 lanthanide-dependent methanol dehydrogenaseAdvanced search results
results (
results (Substrates Products
Substrates Products on EC 1.1.2.10 - lanthanide-dependent methanol dehydrogenase
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
acetaldehyde + reduced phenazine ethosulfate
ethanol + phenazine ethosulfate
-
less than 50% activity compared to methanol
-
-
?
methanol + oxidized cytochrome c XoxG
formaldehyde + reduced cytochrome c XoxG
-
-
-
-
?
1-butanol + phenazine ethosulfate
butyraldehyde + reduced phenazine ethosulfate
-
78.3% activity compared to methanol
-
-
r
1-butanol + phenazine ethosulfate
butyraldehyde + reduced phenazine ethosulfate
-
78.3% activity compared to methanol
-
-
r
1-butanol + phenazine ethosulfate
butyraldehyde + reduced phenazine ethosulfate
-
100% activity compared to methanol
-
-
?
1-butanol + phenazine ethosulfate
butyraldehyde + reduced phenazine ethosulfate
-
100% activity compared to methanol
-
-
?
1-butanol + phenazine methosulfate
butyraldehyde + reduced phenazine methosulfate
-
more than 95% activity compared to methanol
-
-
r
1-butanol + phenazine methosulfate
butyraldehyde + reduced phenazine methosulfate
-
more than 95% activity compared to methanol
-
-
r
1-hexanol + phenazine ethosulfate
hexaldehyde + reduced phenazine ethosulfate
-
100% activity compared to methanol
-
-
?
1-hexanol + phenazine ethosulfate
hexaldehyde + reduced phenazine ethosulfate
-
100% activity compared to methanol
-
-
?
1-hexanol + phenazine methosulfate
hexaldehyde + reduced phenazine methosulfate
-
more than 95% activity compared to methanol
-
-
r
1-hexanol + phenazine methosulfate
hexaldehyde + reduced phenazine methosulfate
-
more than 95% activity compared to methanol
-
-
r
1-propanol + phenazine ethosulfate
propionaldehyde + reduced phenazine ethosulfate
-
85.3% activity compared to methanol
-
-
r
1-propanol + phenazine ethosulfate
propionaldehyde + reduced phenazine ethosulfate
-
85.3% activity compared to methanol
-
-
r
1-propanol + phenazine ethosulfate
propionaldehyde + reduced phenazine ethosulfate
-
100% activity compared to methanol
-
-
?
1-propanol + phenazine methosulfate
propionaldehyde + reduced phenazine methosulfate
-
more than 95% activity compared to methanol
-
-
r
1-propanol + phenazine methosulfate
propionaldehyde + reduced phenazine methosulfate
-
more than 95% activity compared to methanol
-
-
r
1-propanol + phenazine methosulfate
propionaldehyde + reduced phenazine methosulfate
-
more than 95% activity compared to methanol
-
-
r
2-propanol + phenazine ethosulfate
?
-
0.775% activity compared to methanol
-
-
r
2-propanol + phenazine ethosulfate
?
-
0.775% activity compared to methanol
-
-
r
2-propanol + phenazine methosulfate
?
-
40% activity compared to methanol
-
-
r
2-propanol + phenazine methosulfate
?
-
subtype XoxF4-1 shows 20% activity compared to methanol, subtype XoxF4-2 shows 5% activity compared to methanol
-
-
r
acetaldehyde + reduced phenazine methosulfate
ethanol + phenazine methosulfate
-
60% activity compared to methanol
-
-
r
acetaldehyde + reduced phenazine methosulfate
ethanol + phenazine methosulfate
-
subtype XoxF4-1 shows 50% activity compared to methanol, subtype XoxF4-2 shows 15% activity compared to methanol
-
-
r
acetaldehyde + reduced phenazine methosulfate
ethanol + phenazine methosulfate
-
subtype XoxF4-1 shows 50% activity compared to methanol, subtype XoxF4-2 shows 15% activity compared to methanol
-
-
r
ethanol + phenazine ethosulfate
acetaldehyde + reduced phenazine ethosulfate
-
93% activity compared to methanol
-
-
r
ethanol + phenazine ethosulfate
acetaldehyde + reduced phenazine ethosulfate
-
93% activity compared to methanol
-
-
r
ethanol + phenazine ethosulfate
acetaldehyde + reduced phenazine ethosulfate
-
100% activity compared to methanol
-
-
?
ethanol + phenazine methosulfate
acetaldehyde + reduced phenazine methosulfate
-
more than 95% activity compared to methanol
-
-
r
ethanol + phenazine methosulfate
acetaldehyde + reduced phenazine methosulfate
highest activity
-
-
r
ethanol + phenazine methosulfate
acetaldehyde + reduced phenazine methosulfate
-
best substrate for ExaF
-
-
?
ethanol + phenazine methosulfate
acetaldehyde + reduced phenazine methosulfate
-
more than 95% activity compared to methanol
-
-
r
ethanol + phenazine methosulfate
acetaldehyde + reduced phenazine methosulfate
-
more than 95% activity compared to methanol
-
-
r
formaldehyde + phenazine methosulfate + ?
formate + reduced phenazine methosulfate + ?
-
-
-
?
formaldehyde + phenazine methosulfate + ?
formate + reduced phenazine methosulfate + ?
-
-
-
?
formaldehyde + reduced phenazine ethosulfate
methanol + phenazine ethosulfate
-
91.5% activity compared to methanol
-
-
r
formaldehyde + reduced phenazine ethosulfate
methanol + phenazine ethosulfate
-
100% activity compared to methanol
-
-
r
formaldehyde + reduced phenazine methosulfate
methanol + phenazine methosulfate
-
more than 95% activity compared to methanol
-
-
r
formaldehyde + reduced phenazine methosulfate
methanol + phenazine methosulfate
the enzyme is 100times more efficient at oxidizing formaldehyde than methanol
-
-
r
formaldehyde + reduced phenazine methosulfate
methanol + phenazine methosulfate
-
more than 95% activity compared to methanol
-
-
r
methanol + 2 cytochrome cGJ
formaldehyde + 2 reduced cytochrome cGJ
-
-
-
-
r
methanol + 2 cytochrome cGJ
formaldehyde + 2 reduced cytochrome cGJ
-
electrochemic reaction, use of a Au/MU electrode for the electrontransfer process. The attenuation coefficient of DCPIP is known to be very sensitive to changes in pH, reactions with DCPIP are monitored at 600 nm
-
-
r
methanol + 2 cytochrome cGJ
formaldehyde + 2 reduced cytochrome cGJ
-
electrochemical redox reaction
-
-
r
methanol + 2 cytochrome cGJ
formaldehyde + 2 reduced cytochrome cGJ
-
-
-
-
r
methanol + 2 cytochrome cGJ
formaldehyde + 2 reduced cytochrome cGJ
-
electrochemical redox reaction
-
-
r
methanol + 2 cytochrome cGJ
formaldehyde + 2 reduced cytochrome cGJ
-
-
-
-
r
methanol + 2 cytochrome cGJ
formaldehyde + 2 reduced cytochrome cGJ
-
electrochemic reaction, use of a Au/MU electrode for the electrontransfer process. The attenuation coefficient of DCPIP is known to be very sensitive to changes in pH, reactions with DCPIP are monitored at 600 nm
-
-
r
methanol + 2 cytochrome cGJ
formaldehyde + 2 reduced cytochrome cGJ
-
-
-
r
methanol + 2 cytochrome cGJ
formaldehyde + 2 reduced cytochrome cGJ
-
-
-
r
methanol + 2 cytochrome cGJ
formaldehyde + 2 reduced cytochrome cGJ
-
-
-
r
methanol + 2 cytochrome cGJ
formaldehyde + 2 reduced cytochrome cGJ
-
-
-
r
methanol + 2 cytochrome cGJ
formaldehyde + 2 reduced cytochrome cGJ
-
-
-
r
methanol + 2 oxidized cytochrome cGJ
formaldehyde + 2 reduced cytochrome cGJ
-
-
-
-
?
methanol + 2 oxidized cytochrome cGJ
formaldehyde + 2 reduced cytochrome cGJ
-
-
-
-
?
methanol + 2 oxidized cytochrome cL
formaldehyde + 2 reduced cytochrome cL
-
-
-
-
?
methanol + 2 oxidized cytochrome cL
formaldehyde + 2 reduced cytochrome cL
-
-
-
-
?
methanol + 2 oxidized cytochrome cL
formaldehyde + 2 reduced cytochrome cL
-
-
-
?
methanol + 2 oxidized cytochrome cL
formaldehyde + 2 reduced cytochrome cL
c-type cytochrome XoxG
-
-
?
methanol + phenazine ethosulfate
formaldehyde + reduced phenazine ethosulfate
-
100% activity
-
-
r
methanol + phenazine ethosulfate
formaldehyde + reduced phenazine ethosulfate
-
100% activity
-
-
r
methanol + phenazine ethosulfate
formaldehyde + reduced phenazine ethosulfate
-
-
-
-
?
methanol + phenazine ethosulfate
formaldehyde + reduced phenazine ethosulfate
-
100% activity
-
-
r
methanol + phenazine ethosulfate
formaldehyde + reduced phenazine ethosulfate
-
-
-
-
?
methanol + phenazine ethosulfate
formaldehyde + reduced phenazine ethosulfate
-
100% activity
-
-
r
methanol + phenazine ethosulfate
formaldehyde + reduced phenazine ethosulfate
-
-
-
-
?
methanol + phenazine ethosulfate
formaldehyde + reduced phenazine ethosulfate
-
-
-
?
methanol + phenazine ethosulfate
formaldehyde + reduced phenazine ethosulfate
-
-
-
?
methanol + phenazine methosulfate
formaldehyde + reduced phenazine ethosulfate
-
methanol is the preferred substrate
-
-
?
methanol + phenazine methosulfate
formaldehyde + reduced phenazine ethosulfate
Grimontia marina CECT 8713
-
methanol is the preferred substrate
-
-
?
methanol + phenazine methosulfate
formaldehyde + reduced phenazine ethosulfate
-
methanol is the preferred substrate
-
-
?
methanol + phenazine methosulfate
formaldehyde + reduced phenazine ethosulfate
Rhodovulum kholense DSM 19783
-
methanol is the preferred substrate
-
-
?
methanol + phenazine methosulfate
formaldehyde + reduced phenazine methosulfate
-
methanol is the preferred substrate
-
-
?
methanol + phenazine methosulfate
formaldehyde + reduced phenazine methosulfate
-
methanol is the preferred substrate
-
-
?
methanol + phenazine methosulfate
formaldehyde + reduced phenazine methosulfate
-
-
-
-
?
methanol + phenazine methosulfate
formaldehyde + reduced phenazine methosulfate
-
-
-
-
?
methanol + phenazine methosulfate
formaldehyde + reduced phenazine methosulfate
-
100% activity
-
-
r
methanol + phenazine methosulfate
formaldehyde + reduced phenazine methosulfate
-
phenazine methosulfate or phenazine ethosulfate and DCPIP coupled assay is the method of choice for methynol dehydrogenasae kinetic analysis and can yield reproducible results when the components are handled correctly
-
-
?
methanol + phenazine methosulfate
formaldehyde + reduced phenazine methosulfate
-
100% activity
-
-
r
methanol + phenazine methosulfate
formaldehyde + reduced phenazine methosulfate
-
-
-
-
?
methanol + phenazine methosulfate
formaldehyde + reduced phenazine methosulfate
-
phenazine methosulfate or phenazine ethosulfate and DCPIP coupled assay is the method of choice for methynol dehydrogenasae kinetic analysis and can yield reproducible results when the components are handled correctly
-
-
?
methanol + phenazine methosulfate
formaldehyde + reduced phenazine methosulfate
-
-
-
-
?
methanol + phenazine methosulfate
formaldehyde + reduced phenazine methosulfate
-
-
-
?
methanol + phenazine methosulfate
formaldehyde + reduced phenazine methosulfate
-
-
-
-
?
methanol + phenazine methosulfate
formaldehyde + reduced phenazine methosulfate
-
-
-
-
?
methanol + phenazine methosulfate
formaldehyde + reduced phenazine methosulfate
-
-
-
?
methanol + phenazine methosulfate
formaldehyde + reduced phenazine methosulfate
-
-
-
-
?
methanol + phenazine methosulfate
formaldehyde + reduced phenazine methosulfate
-
100% activity
-
-
r
methanol + phenazine methosulfate
formaldehyde + reduced phenazine methosulfate
-
methanol is the preferred substrate
-
-
?
methanol + phenazine methosulfate
formaldehyde + reduced phenazine methosulfate
-
-
-
-
?
methanol + phenazine methosulfate
formaldehyde + reduced phenazine methosulfate
-
-
-
r
methanol + phenazine methosulfate
formaldehyde + reduced phenazine methosulfate
-
-
-
?
methanol + phenazine methosulfate
formaldehyde + reduced phenazine methosulfate
-
best substrate for XoxF1
-
-
?
methanol + phenazine methosulfate
formaldehyde + reduced phenazine methosulfate
-
methanol is the preferred substrate
-
-
?
methanol + phenazine methosulfate
formaldehyde + reduced phenazine methosulfate
phenazine methosulfate or phenazine ethosulfate and DCPIP coupled assay is the method of choice for methynol dehydrogenasae kinetic analysis and can yield reproducible results when the components are handled correctly
-
-
?
methanol + phenazine methosulfate
formaldehyde + reduced phenazine methosulfate
-
-
-
-
?
methanol + phenazine methosulfate
formaldehyde + reduced phenazine methosulfate
-
100% activity
-
-
r
methanol + phenazine methosulfate
formaldehyde + reduced phenazine methosulfate
-
methanol is the preferred substrate
-
-
?
methanol + phenazine methosulfate
formaldehyde + reduced phenazine methosulfate
-
100% activity
-
-
r
methanol + phenazine methosulfate
formaldehyde + reduced phenazine methosulfate
-
-
-
-
?
methanol + phenazine methosulfate
formaldehyde + reduced phenazine methosulfate
-
methanol is the preferred substrate
-
-
?
methanol + phenazine methosulfate
formaldehyde + reduced phenazine methosulfate
-
-
-
-
?
methanol + phenazine methosulfate
formaldehyde + reduced phenazine methosulfate
-
-
-
?
methanol + phenazine methosulfate
formaldehyde + reduced phenazine methosulfate
-
-
-
?
methanol + phenazine methosulfate
formaldehyde + reduced phenazine methosulfate
-
-
-
-
?
methanol + phenazine methosulfate
formaldehyde + reduced phenazine methosulfate
methanol is the preferred substrate
-
-
?
methanol + phenazine methosulfate
formaldehyde + reduced phenazine methosulfate
methanol is the preferred substrate
-
-
?
methanol + phenazine methosulfate
formaldehyde + reduced phenazine methosulfate
-
methanol is the preferred substrate
-
-
?
methanol + phenazine methosulfate
formaldehyde + reduced phenazine methosulfate
-
methanol is the preferred substrate
-
-
?
methanol + phenazine methosulfate
formaldehyde + reduced phenazine methosulfate
-
methanol is the preferred substrate
-
-
?
methanol + phenazine methosulfate
formaldehyde + reduced phenazine methosulfate
Tistlia consotensis DSM 21585
-
methanol is the preferred substrate
-
-
?
methanol + Wurster's Blue
formaldehyde + ?
-
the one-electron acceptor and dye Wurster's Blue presents an easy method for routine methanol dehydrogenase assays, for example, identifying methanol dehydrogenase containing fractions during enzyme purification. Due to its low stability at alkaline pH, phenazine ethosulfate-2,6-dichlorophenolindophenol is preferable to Wurster's Blue as electron acceptor/dye for determining the kinetic parameters
-
-
?
methanol + Wurster's Blue
formaldehyde + ?
-
the one-electron acceptor and dye Wurster's Blue presents an easy method for routine methanol dehydrogenase assays, for example, identifying methanol dehydrogenase containing fractions during enzyme purification. Due to its low stability at alkaline pH, phenazine ethosulfate-2,6-dichlorophenolindophenol is preferable to Wurster's Blue as electron acceptor/dye for determining the kinetic parameters
-
-
?
methanol + Wurster's Blue
formaldehyde + ?
the one-electron acceptor and dye Wurster's Blue presents an easy method for routine methanol dehydrogenase assays, for example, identifying methanol dehydrogenase containing fractions during enzyme purification. Due to its low stability at alkaline pH, phenazine ethosulfate-2,6-dichlorophenolindophenol is preferable to Wurster's Blue as electron acceptor/dye for determining the kinetic parameters
-
-
?
propionaldehyde + reduced phenazine methosulfate
1-propanol + phenazine methosulfate
-
60% activity compared to methanol
-
-
r
propionaldehyde + reduced phenazine methosulfate
1-propanol + phenazine methosulfate
-
subtype XoxF4-1 shows 50% activity compared to methanol, subtype XoxF4-2 shows 15% activity compared to methanol
-
-
r
propionaldehyde + reduced phenazine methosulfate
1-propanol + phenazine methosulfate
-
subtype XoxF4-1 shows 50% activity compared to methanol, subtype XoxF4-2 shows 15% activity compared to methanol
-
-
r
additional information
?
-
-
no activity with 2-propanol and formate
-
-
-
additional information
?
-
-
no activity with 2-propanol and formate
-
-
-
additional information
?
-
for assay of chromatography fractions during purifications, activity can be determined by reduction of 2,6-dichlorophenolindolphenol (DCPIP) using phenazine ethosulfate (PES) as an electron acceptor. Development of ddifferent assay methods, detailed overview
-
-
-
additional information
?
-
-
MDH activity is also spectrophotometrically monitored via the reduction of 2,6-dichlorophenolindophenol (DCPIP) by the MDH with either phenazine ethosulfate or phenazine methosulfate as mediator. XoxG exhibits an unusually low reduction potential. The reduction potential of XoxG may be specifically optimized for transfer of electrons from PQQ, bound to lighter LnIIIs, to the cytochrome
-
-
-
additional information
?
-
MDH activity is also spectrophotometrically monitored via the reduction of 2,6-dichlorophenolindophenol (DCPIP) by the MDH with either phenazine ethosulfate or phenazine methosulfate as mediator. XoxG exhibits an unusually low reduction potential. The reduction potential of XoxG may be specifically optimized for transfer of electrons from PQQ, bound to lighter LnIIIs, to the cytochrome
-
-
-
additional information
?
-
MDH activity is also spectrophotometrically monitored via the reduction of 2,6-dichlorophenolindophenol (DCPIP) by the MDH with either phenazine ethosulfate or phenazine methosulfate as mediator. XoxG exhibits an unusually low reduction potential. The reduction potential of XoxG may be specifically optimized for transfer of electrons from PQQ, bound to lighter LnIIIs, to the cytochrome
-
-
-
additional information
?
-
for assay of chromatography fractions during purifications, activity can be determined by reduction of 2,6-dichlorophenolindolphenol (DCPIP) using phenazine ethosulfate (PES) as an electron acceptor. Development of ddifferent assay methods, detailed overview
-
-
-
additional information
?
-
MDH activity is also spectrophotometrically monitored via the reduction of 2,6-dichlorophenolindophenol (DCPIP) by the MDH with either phenazine ethosulfate or phenazine methosulfate as mediator. XoxG exhibits an unusually low reduction potential. The reduction potential of XoxG may be specifically optimized for transfer of electrons from PQQ, bound to lighter LnIIIs, to the cytochrome
-
-
-
additional information
?
-
for assay of chromatography fractions during purifications, activity can be determined by reduction of 2,6-dichlorophenolindolphenol (DCPIP) using phenazine ethosulfate (PES) as an electron acceptor. Development of ddifferent assay methods, detailed overview
-
-
-
additional information
?
-
MDH activity is also spectrophotometrically monitored via the reduction of 2,6-dichlorophenolindophenol (DCPIP) by the MDH with either phenazine ethosulfate or phenazine methosulfate as mediator. XoxG exhibits an unusually low reduction potential. The reduction potential of XoxG may be specifically optimized for transfer of electrons from PQQ, bound to lighter LnIIIs, to the cytochrome
-
-
-
additional information
?
-
for assay of chromatography fractions during purifications, activity can be determined by reduction of 2,6-dichlorophenolindolphenol (DCPIP) using phenazine ethosulfate (PES) as an electron acceptor. Development of ddifferent assay methods, detailed overview
-
-
-
additional information
?
-
MDH activity is also spectrophotometrically monitored via the reduction of 2,6-dichlorophenolindophenol (DCPIP) by the MDH with either phenazine ethosulfate or phenazine methosulfate as mediator. XoxG exhibits an unusually low reduction potential. The reduction potential of XoxG may be specifically optimized for transfer of electrons from PQQ, bound to lighter LnIIIs, to the cytochrome
-
-
-
additional information
?
-
for assay of chromatography fractions during purifications, activity can be determined by reduction of 2,6-dichlorophenolindolphenol (DCPIP) using phenazine ethosulfate (PES) as an electron acceptor. Development of ddifferent assay methods, detailed overview
-
-
-
